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April 2017 Briefing - Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for April 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Meeting Organizers Overlooking Qualified Female Scientists

FRIDAY, April 28, 2017 (HealthDay News) -- Invited speakers at medical conferences tend to be disproportionately male, a disparity that can be addressed by actively preparing lists of potential speakers, according to a study published online April 18 in Nature Immunology.

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Exercise Reduces Weight Gain Effects in Those With FTO Gene

FRIDAY, April 28, 2017 (HealthDay News) -- Eleven novel adiposity variants have been identified after adjustment for physical activity (PA), and PA can reduce the weight-gaining effects of the FTO gene by about 30 percent, according to a meta-analysis published online April 27 in PLOS Genetics.

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Distinct Bacterial Taxa in ME/CSF Subgroups With/Without IBS

FRIDAY, April 28, 2017 (HealthDay News) -- Distinct bacterial taxa are seen in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) subgroups, defined by the presence of irritable bowel syndrome (IBS), according to a study published online April 27 in Microbiome.

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Routine Blood Tests Can Harm Patient Care

FRIDAY, April 28, 2017 (HealthDay News) -- Routine blood tests waste money and can damage patient care, according to an opinion piece published online April 27 in the BMJ.

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Algorithm Integrated Into App Forecasts Glucose Levels

FRIDAY, April 28, 2017 (HealthDay News) -- A mechanistic model based on Gaussian process models and data assimilation can produce a personalized, nutrition-based glucose forecast for individuals with type 2 diabetes, according to a study published online April 27 in PLOS Computational Biology.

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Single-Payer Health System Bill Moves Forward in California

THURSDAY, April 27, 2017 (HealthDay News) -- A proposal to replace private insurance with government-funded health care for all moved forward in California on Wednesday as Democrats on the Senate Health Committee voted to advance the measure.

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Risk Factors in Six Areas Tied to Physician Burnout

THURSDAY, April 27, 2017 (HealthDay News) -- Physician burnout factors include control, whether there is time to deliver excellent care, and whether the workplace is fair, according to a presentation at the Medical Group Management Association/American Medical Association 2017 Collaborate in Practice Conference, held April 9 to 11 in Chicago.

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Pediatricians Missing Elevated Blood Lead Levels in U.S.

THURSDAY, April 27, 2017 (HealthDay News) -- Many children with a blood lead level ≥10 µg/dL (elevated blood lead level [EBLL]) are being missed by pediatric care providers, according to a study published online April 27 in Pediatrics.

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Early RA Treatment Important for Long-Term Outcomes

THURSDAY, April 27, 2017 (HealthDay News) -- Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes, and there has been a decrease in mortality rates attributable to RA, according to two studies published online April 20 in Arthritis & Rheumatology.

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Genetic Variant Tied to MS and Systemic Lupus Identified

THURSDAY, April 27, 2017 (HealthDay News) -- A genetic variant that is associated with both multiple sclerosis and systemic lupus erythematosus (SLE) has been identified, according to a study published online April 26 in the New England Journal of Medicine.

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Gene Expression Profile Improves ID of High-Risk Melanoma

THURSDAY, April 27, 2017 (HealthDay News) -- A validated 31-gene expression profile (GEP) signature improves identification of patients with melanoma at high risk of metastasis when used in combination with the American Joint Committee on Cancer (AJCC) outcome prediction tool, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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Chromosome Instability Test Prognostic in NSCLC

WEDNESDAY, April 26, 2017 (HealthDay News) -- Chromosome instability within lung cancer tumors increases the risk of recurrence or death and may help forecast recurrence long before standard tests, according to a study published online April 26 in the New England Journal of Medicine and Nature.

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CDC: Opioid-Related Mortality Rate Might Be Underestimated

WEDNESDAY, April 26, 2017 (HealthDay News) -- The prescription drug abuse epidemic in the United States might be associated with a higher mortality rate than has been reported previously, according to a report from the U.S. Centers for Disease Control and Prevention presented April 24 at the Epidemic Intelligence Service conference in Atlanta.

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Pollution Linked to Destructive Effect on Upper Sinonasal Airway

WEDNESDAY, April 26, 2017 (HealthDay News) -- Exposure of the sinonasal airway barrier to chronic airborne particulate matter has destructive effects, including release of pro-inflammatory cytokines, according to an experimental study published online Feb. 28 in the American Journal of Respiratory Cell and Molecular Biology.

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Postbiotic Could Lower Glucose, Inflammation in Obesity

WEDNESDAY, April 26, 2017 (HealthDay News) -- The bacterial cell wall-derived muramyl dipeptide (MDP) postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice, according to an experimental study published online April 20 in Cell Metabolism.

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Molecular Autopsy IDs Causes of Sudden Arrhythmic Death

WEDNESDAY, April 26, 2017 (HealthDay News) -- Molecular autopsy for electrical disorder and cardiomyopathy genes identifies a modest but realistic yield in sudden arrhythmic death syndrome (SADS), according to a study published online April 24 in the Journal of the American College of Cardiology.

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Blood-Based Genome Testing Feasible for Rapid Mutation Assay

WEDNESDAY, April 26, 2017 (HealthDay News) -- A blood-based genome testing service provides accurate results within 72 hours, according to a study published online April 19 in the Journal of Molecular Diagnostics.

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Deep Convolutional Neural Networks Accurately Detect TB

WEDNESDAY, April 26, 2017 (HealthDay News) -- Deep learning with deep convolutional neural networks (DCNNs) can result in accurate detection of tuberculosis (TB) on chest radiographs, according to a study published online April 25 in Radiology.

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Fatal Case of Suspected Propofol-Induced Pancreatitis Described

WEDNESDAY, April 26, 2017 (HealthDay News) -- A fatal case of propofol-induced acute necrotizing pancreatitis has been described in a case report published online April 10 in the Journal of Clinical Pharmacy and Therapeutics.

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Post-Op hsTnT Linked to 30-Day Mortality After Noncardiac Sx

TUESDAY, April 25, 2017 (HealthDay News) -- Peak postoperative high-sensitivity troponin T (hsTnT) is associated with increased risk of 30-day mortality among patients undergoing noncardiac surgery, according to a study published online April 25 in the Journal of the American Medical Association.

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HBV Reactivation Is Concern With DAA Tx in HBV-HCV Coinfection

TUESDAY, April 25, 2017 (HealthDay News) -- Hepatitis B virus (HBV) reactivation (HBV-R) is a safety concern for patients with HBV and hepatitis C virus (HCV) coinfection receiving direct-acting antiviral agents (DAAs), according to a study published online April 24 in the Annals of Internal Medicine.

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T2DM Risk Cut by Variant in Sulfonylurea Receptor Encoder

TUESDAY, April 25, 2017 (HealthDay News) -- A common missense variant in the gene encoding a component of the sulfonylurea receptor (ABCC8 p.A1369S), which promotes closure of the target channel of sulfonylurea therapy, mimicking the effects of therapy, is associated with reduced risk of type 2 diabetes and coronary heart disease, according to a study published online April 14 in Diabetes.

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Neutrophil-to-Lymphocyte Ratio Predicts Mortality in CAP

MONDAY, April 24, 2017 (HealthDay News) -- Neutrophil-to-lymphocyte ratio (NLR) can predict 30-day mortality for elderly adults with community-acquired pneumonia (CAP), according to a study published online April 13 in the Journal of the American Geriatrics Society.

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PSA Screening Rates Have Leveled Off in U.S.

TUESDAY, April 25, 2017 (HealthDay News) -- Rates of prostate-specific antigen (PSA) screening have leveled off after declining for a number of years in the United States, according to a research letter published online April 24 in JAMA Internal Medicine.

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Gene Therapy Strategy Feasible for Retinitis Pigmentosa

MONDAY, April 24, 2017 (HealthDay News) -- A gene therapy strategy can be applied to retinitis pigmentosa, with switching rod to cone-like photoreceptors feasible for restoring visual function, according to an experimental study published online April 21 in Cell Research.

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Only Select Incidental Thyroid Nodules Need Further Evaluation

MONDAY, April 24, 2017 (HealthDay News) -- Only a few select incidental thyroid nodules require further evaluation, according to a review published online April 20 in JAMA Otolaryngology-Head & Neck Surgery.

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Black Men Have Higher Rate of Preclinical Prostate Cancer

MONDAY, April 24, 2017 (HealthDay News) -- Black men appear to have a higher incidence of preclinical prostate cancer and a higher risk of metastatic progression than the general population, which may warrant a change in screening approach, according to a study published online April 24 in Cancer.

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Case Report Describes Adverse Reaction to Clindamycin

FRIDAY, April 21, 2017 (HealthDay News) -- In a case report published online April 17 in the Journal of Clinical Pharmacy and Therapeutics, acute generalized exanthematous pustulosis secondary to clindamycin therapy is described.

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Microvascular Endothelial Dysfunction Can Predict Dementia

FRIDAY, April 21, 2017 (HealthDay News) -- Markers of microvascular endothelial dysfunction can predict dementia, according to a study published online April 13 in the Journal of Internal Medicine.

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Surveillance Biopsy Timing Not Tied to Reclassification

FRIDAY, April 21, 2017 (HealthDay News) -- Timing of the first active surveillance biopsy is not associated with increased adverse reclassification of prostate cancer, according to a study published in the April issue of The Journal of Urology.

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First-Void Morning Urine Not Necessary for CIN2+ Detection

THURSDAY, April 20, 2017 (HealthDay News) -- There is no advantage in testing morning first-void urine over later samples for cervical intraepithelial neoplasia grade 2+ (CIN2+) detection using human papillomavirus (HPV) testing, according to a study published online April 9 in BJOG: An International Journal of Obstetrics and Gynaecology.

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CDC: Salmonella Infection Prevalence Down in 2016

THURSDAY, April 20, 2017 (HealthDay News) -- U.S. health officials have made progress against Salmonella infections, according to research published in the April 21 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Hantavirus Pulmonary Syndrome Risk Up for Some Populations

THURSDAY, April 20, 2017 (HealthDay News) -- Individuals in certain occupations and in certain populations may be more at risk of hantavirus pulmonary syndrome, according to research published in the May issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Circulating Exosomes Have Distinct RNA Profile in MS

THURSDAY, April 20, 2017 (HealthDay News) -- Circulating exosomes have a distinct RNA profile in relapsing-remitting multiple sclerosis (RRMS), according to a study published online April 15 in the Annals of Neurology.

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Hypertension May Positively Affect Ovarian Cancer Prognosis

WEDNESDAY, April 19, 2017 (HealthDay News) -- A woman's prognosis after an ovarian cancer diagnosis may be affected by a number of unexpected factors, according to a review published recently in Cancer Causes & Control.

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Study Looks at ER Visits for Patients Injured by Police in U.S.

WEDNESDAY, April 19, 2017 (HealthDay News) -- More than 50,000 Americans are treated each year for injuries inflicted by police, according to a research letter published online April 19 in JAMA Surgery.

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Chagas Disease Presents Public Health Challenge in the U.S.

WEDNESDAY, April 19, 2017 (HealthDay News) -- Chagas disease, caused by the parasite Trypanosoma cruzi and transmitted by the triatomine bug, is a public health concern in the United States, according to the Drugs for Neglected Diseases Initiative (DNDi).

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Researchers Warn of Epilepsy in Zika-Infected Infants

WEDNESDAY, April 19, 2017 (HealthDay News) -- Beyond its known links to birth defects and other issues, the Zika virus may also trigger cases of epilepsy in infants, according to a viewpoint piece published online April 17 in JAMA Neurology.

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Long-Term Eye Health at Risk in Infants Born With Zika Infection

TUESDAY, April 18, 2017 (HealthDay News) -- Zika virus may lead to lifelong vision impairment in affected infants, according to research published online April 13 in JAMA Ophthalmology.

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No Proof Azithromycin Ups Odds of Ventricular Arrhythmia

TUESDAY, April 18, 2017 (HealthDay News) -- Azithromycin doesn't appear to increase the risk of ventricular arrhythmia, according to a study published online April 18 in CMAJ, the journal of the Canadian Medical Association.

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Over 20 Percent of Maternal Mortality in Illinois Due to CVD

TUESDAY, April 18, 2017 (HealthDay News) -- More than one in five maternal deaths in Illinois in 2002 to 2011 were attributable to cardiovascular disease, according to a study published in the May issue of Obstetrics & Gynecology.

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Increase in Prostate Needle Biopsy-Linked Infection in N.Y.

TUESDAY, April 18, 2017 (HealthDay News) -- Infectious complications after prostate needle biopsy increased from 2011 to 2014 across New York State, according to a study published in the April issue of The Journal of Urology.

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Doctors Need to Be Mindful of What They Post on Social Media

MONDAY, April 17, 2017 (HealthDay News) -- Young doctors often have unprofessional or offensive content on their Facebook profiles, according to a study published online April 9 in BJU International.

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Cervical Cancer Screen Rates Low for Women With Mental Illness

MONDAY, April 17, 2017 (HealthDay News) -- Cervical cancer screening rates are much lower among women with severe mental illness than among other women, according to a study published online April 17 in Psychiatric Services.

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RUNX1 May Play Role in Proliferative Diabetic Retinopathy

MONDAY, April 17, 2017 (HealthDay News) -- The Runt-related transcription factor 1 (RUNX1) gene may play a role in human proliferative diabetic retinopathy (PDR), and upregulation may be a marker of aberrant retinal angiogenesis, according to a study published online April 11 in Diabetes.

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ASCO Updates Recs on Potentially Curable Pancreatic Cancer

MONDAY, April 17, 2017 (HealthDay News) -- Guidelines relating to the appropriate adjuvant regimen for patients with pancreatic cancer have been updated in light of new evidence, according to a special article published online April 11 in the Journal of Clinical Oncology.

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Anthrax Cases Linked to Use of Vintage Shaving Brushes

MONDAY, April 17, 2017 (HealthDay News) -- During and after the First World War, there was an increase in anthrax cases associated with use of new shaving brushes, which were made of imported horsehair, according to research published in the May issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Breast Cancer Rates Increasing Among Asian-American Women

FRIDAY, April 14, 2017 (HealthDay News) -- Breast cancer rates among Asian-Americans are steadily rising in contrast to other racial/ethnic groups, according to a study published online April 1 in Breast Cancer Research and Treatment.

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Reduced Glomerular Filtration Rate Major Cause of CV Deaths

FRIDAY, April 14, 2017 (HealthDay News) -- Kidney disease is a major cause of cardiovascular deaths worldwide, according to a study published online April 13 in the Journal of the American Society of Nephrology.

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Cancer Occurrence Differs Among African-Born, U.S.-Born Blacks

THURSDAY, April 13, 2017 (HealthDay News) -- Cancer rates differ between African- and U.S.-born black Americans, with cancer rates varying by region of birth in Africa, according to a study published online April 13 in Cancer.

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Accurate Diagnosis of Endocrine Hypertension Important

THURSDAY, April 13, 2017 (HealthDay News) -- An accurate diagnosis of endocrine hypertension allows clinicians to provide effective treatment, including a surgical cure or to achieve an optimal response with specific pharmacologic therapy, according to a scientific statement published online April 5 in Endocrine Reviews.

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Diabetes Continues to Be a Significant Public Health Burden

THURSDAY, April 13, 2017 (HealthDay News) -- The incidence of diabetes is increasing among young persons, although some progress is seen with mortality and incidence of cardiovascular outcomes among patients with the disease, according to research published in the April 13 issue of the New England Journal of Medicine.

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Misunderstanding of BRCA Test Results Affects Mastectomy Rates

THURSDAY, April 13, 2017 (HealthDay News) -- Close to half of breast cancer patients who choose to have a double mastectomy after genetic testing may not have the gene mutations known to raise the risk of additional cancers, according to a study published online April 12 in the Journal of Clinical Oncology.

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24-Hour Urine Collection of Unclear Benefit in Stone Formers

THURSDAY, April 13, 2017 (HealthDay News) -- Despite guidelines, it has not been established whether all recurrent kidney stone formers benefit from 24-hour urine collection, according to a review published in the April issue of The Journal of Urology.

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Mortality Up With Depression Just Before Breast Cancer Diagnosis

THURSDAY, April 13, 2017 (HealthDay News) -- Women with newly-developed depression before a breast cancer diagnosis have a modestly, but significantly, increased risk for death, according to a study published online April 7 in Cancer.

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Midlife Vascular Risk Factors Associated With Elevated Amyloid

WEDNESDAY, April 12, 2017 (HealthDay News) -- Individuals with risk factors for cardiovascular disease and stroke in middle age are more likely to have elevated levels of amyloid, according to a study published in the April 11 issue of the Journal of the American Medical Association.

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Barrett's With Irregular Z Line Unlikely to Progress Quickly

WEDNESDAY, April 12, 2017 (HealthDay News) -- There is a low risk of development of high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) among patients with Barrett's esophagus (BE) of <1 cm (irregular Z line) within five years of index endoscopy, according to a study published in the April issue of Gastroenterology.

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Patient Choice Stressed in Latest USPSTF PSA Screening Recs

TUESDAY, April 11, 2017 (HealthDay News) -- The U.S. Preventive Services Task Force is recommending that men aged 55 to 69 have a discussion with their doctor about the pros and cons of prostate-specific antigen (PSA) screening for detecting prostate cancer.

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Acute Ischemic Stroke Prevalence Up in Younger Americans

TUESDAY, April 11, 2017 (HealthDay News) -- Acute ischemic stroke is increasingly prevalent in Americans under 65, as is the percentage of those with three or more stroke risk factors, according to a study published online April 10 in JAMA Neurology.

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Asymptomatic C. difficile Ups Risk for Other Hospital Patients

TUESDAY, April 11, 2017 (HealthDay News) -- Asymptomatic carriers of toxigenic Clostridium difficile in hospitals increase infection risk in other patients, according to a study published in the April issue of Gastroenterology.

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Eval, Mgmt of RA in Women Can Be Compromised by Obesity

MONDAY, April 10, 2017 (HealthDay News) -- C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels in the evaluation and management of rheumatoid arthritis may be affected by obesity in women, according to a study published online April 10 in Arthritis Care & Research.

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Fungal Lesions Can Mimic Neoplastic Growths on Tongue

MONDAY, April 10, 2017 (HealthDay News) -- Fungal lesions can mimic neoplastic growths on the tongue, according to a case report published online April 5 in Pediatrics.

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U.S. Blood Banks Can Protect Blood Supply From Zika Virus

FRIDAY, April 7, 2017 (HealthDay News) -- U.S. blood banks are confident they have the tools to protect America's blood supply from possible new Zika virus outbreaks during the upcoming mosquito season, according to research published in the March issue of Transfusion, a theme issue on Zika and other transfusion transmitted viruses.

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MACRA Changes Government Approach to Doctor Payment

FRIDAY, April 7, 2017 (HealthDay News) -- Implementation of the Medicare Access and CHIP Reauthorization Act (MACRA) has made fundamental changes to the government's approach to physician payment, according to a March 27 policy brief published in Health Affairs.

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Air Pollution, Ozone Exposure Linked to Breast Density

FRIDAY, April 7, 2017 (HealthDay News) -- Air pollution and ozone exposure may in part explain geographical variation in mammographic density, according to a study published online April 6 in Breast Cancer Research.

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CDC: Syphilis Rates Up Among U.S. Men Who Have Sex With Men

FRIDAY, April 7, 2017 (HealthDay News) -- Syphilis rates among men who have sex with men (MSM) have increased significantly in the past two decades, according to research published in the April 7 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Intestinal Reovirus Infection May Be Cause of Celiac Disease

FRIDAY, April 7, 2017 (HealthDay News) -- A common human intestinal reovirus may trigger some cases of celiac disease, according to a study published in the April 7 issue of Science.

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FDA OKs Marketing of Direct-to-Consumer Genetic Risk Tests

FRIDAY, April 7, 2017 (HealthDay News) -- The U.S. Food and Drug Administration has approved the first home genetic tests for 10 diseases or conditions, including Parkinson's disease and late-onset Alzheimer's.

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CDC: Almost Half of U.S. Men, Women <60 Infected With HPV

THURSDAY, April 6, 2017 (HealthDay News) -- Nearly half of American men and women under 60 have a genital human papillomavirus (HPV) infection, according to an April data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Risk Adjustment, Reinsurance Transfer Offer Financial Benefit

THURSDAY, April 6, 2017 (HealthDay News) -- Risk adjustment and reinsurance transfer programs seem to have been effective for increasing revenues at the expense of claims costs, according to research published in the March issue of Health Affairs.

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Autoantibodies to GPIHBP1 Identified in Chylomicronemia

THURSDAY, April 6, 2017 (HealthDay News) -- Some patients with chylomicronemia have autoantibodies to glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 (GPIHBP1), causing severe hypertriglyceridemia, according to a study published online April 5 in the New England Journal of Medicine.

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Stem Cell-Sheet Transplantation Feasible in Cardiomyopathy

THURSDAY, April 6, 2017 (HealthDay News) -- Stem cell-sheet transplantation shows promise in the treatment of cardiomyopathy, according to research published online April 5 in the Journal of the American Heart Association.

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Higher Risk of Cardiovascular Events With Weight Fluctuations

THURSDAY, April 6, 2017 (HealthDay News) -- Fluctuation in body weight is associated with higher mortality and a higher rate of cardiovascular events -- independent of traditional cardiovascular risk factors -- in patients with coronary artery disease, according to a study published in the April 6 issue of the New England Journal of Medicine.

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Long-Term Antibiotic Use May Up Risk of Colorectal Adenomas

WEDNESDAY, April 5, 2017 (HealthDay News) -- Taking antibiotics for an extended period in early to middle adulthood might increase risk for colorectal adenomas, according to a report published online April 4 in Gut.

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Increased Cancer Risk for Childhood Kidney Recipients

WEDNESDAY, April 5, 2017 (HealthDay News) -- Childhood kidney recipients have increased cancer risk, according to a study published online March 29 in the American Journal of Transplantation.

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CDC: Birth Defects Seen in 1 in 10 U.S. Pregnancies Affected by Zika

WEDNESDAY, April 5, 2017 (HealthDay News) -- One in 10 pregnant U.S. women with confirmed Zika infection in 2016 had a baby with virus-related birth defects, according to research published in the April 4 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Bone, Basal Metabolism Link Depends on Vitamin D Level

WEDNESDAY, April 5, 2017 (HealthDay News) -- For postmenopausal women with type 2 diabetes mellitus (T2DMPW), the correlation between bone metabolism and basal metabolism seems to be dependent on serum 25-hydroxyvitamin D (25[OH]D) levels, according to a study published online March 31 in the Journal of Diabetes Investigation.

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Variation in Occupational Influenza Vaccination Coverage

TUESDAY, April 4, 2017 (HealthDay News) -- There is variation in influenza vaccination coverage by industry and occupation, including among health care personnel and other occupational groups who may have first priority to receive influenza vaccination during a pandemic (tier 1), according to a study published in the April 1 issue of the American Journal of Infection Control.

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Maternal Overweight, Obesity May Increase Childhood Epilepsy

TUESDAY, April 4, 2017 (HealthDay News) -- The rates of childhood epilepsy increase with maternal overweight and obesity, according to a study published online April 3 in JAMA Neurology.

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Maximum BMI Over 16 Years Ups Risk of All-Cause Death

TUESDAY, April 4, 2017 (HealthDay News) -- Maximum body mass index (BMI) over 16 years of weight history is associated with increased risk of all-cause death, according to a study published online April 4 in the Annals of Internal Medicine.

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Protein Expression Predicts Rectal Cancer Outcomes

TUESDAY, April 4, 2017 (HealthDay News) -- Loss of E-cadherin protein expression in the pretherapeutic biopsy of rectal cancer is associated with fewer metastases and improved survival, according to a study published online March 25 in the Journal of Digestive Diseases.

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1990 to 2015 Saw Decrease in Global Child, Adolescent Mortality

TUESDAY, April 4, 2017 (HealthDay News) -- From 1990 to 2015 there was a decrease in global child and adolescent mortality, according to a study published online April 3 in JAMA Pediatrics.

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ANGPTL3 Deficiency Linked to Reduced CAD Risk

MONDAY, April 3, 2017 (HealthDay News) -- Angiopoietin-like 3 (ANGPTL3) deficiency is associated with reduced risk of coronary artery disease (CAD), according to a study published online March 29 in the Journal of the American College of Cardiology.

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