See What HealthDay Can Do For You
Contact Us

January 2016 Briefing - Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for January 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Warns of Lead Poisoning Risk From Cosmetic Clay

FRIDAY, Jan. 29, 2016 (HealthDay News) -- A beauty clay sold at major retail outlets may put users at risk for lead poisoning, the U.S. Food and Drug Administration warned Friday.

More Information

High Level of Tenofovir Resistance for Those With HIV

FRIDAY, Jan. 29, 2016 (HealthDay News) -- HIV resistance to the antiretroviral drug tenofovir (Viread) is common, according to a study published online Jan. 28 in The Lancet Infectious Diseases.

Abstract
Full Text
Editorial (subscription or payment may be required)

Soy Foods May Blunt Reproductive Harm From BPA

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Soy intake may modify the association between bisphenol A (BPA) and fertility in women undergoing assisted reproduction, according to research published online Jan. 27 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text

Severe Reaction to Pneumococcal Vaccines in Patients With CAPS

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the February issue of Arthritis & Rheumatology.

Abstract
Full Text (subscription or payment may be required)

Pre-Op MRI Improves Accuracy for Predicting Extent of DCIS

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Preoperative magnetic resonance imaging (MRI) can add to mammography in predicting the extent of ductal carcinoma in situ (DCIS), according to a study published online Jan. 25 in the Journal of Medical Imaging and Radiation Oncology.

Abstract
Full Text (subscription or payment may be required)

Earlier Age at Menarche Linked to Increased Risk of GDM

FRIDAY, Jan. 29, 2016 (HealthDay News) -- Earlier age at menarche is associated with increased risk of gestational diabetes mellitus (GDM), according to a study published online Jan. 26 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

AMA Highlights Top Four Issues to Promote in State Legislation

THURSDAY, Jan. 28, 2016 (HealthDay News) -- The top four issues that will be promoted in state legislation in 2016 were discussed at the 2016 American Medical Association (AMA) State Legislative Strategy Conference, according to a report published by the AMA.

More Information

HIV Can Replicate in Lymphoid Tissue Despite ART Success

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Even when blood tests of HIV patients on antiretroviral drugs show no sign of the virus, it can still be replicating in lymphoid tissue, according to research published online Jan. 27 in Nature.

Abstract
Full Text (subscription or payment may be required)

New Approach Described for Type 1 Diabetes

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Alginate derivatives have been generated that can overcome the challenge of foreign body response in the use of implanted medical devices, and these materials show promise in diabetes, according to two studies published online Jan. 25 in Nature Biotechnology and Nature Medicine.

Abstract 1
Full Text (subscription or payment may be required)
Abstract 2
Full Text (subscription or payment may be required)

Rosacea Linked to Increased Risk of Glioma

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Rosacea is associated with a significantly increased risk of developing glioma, according to research published online Jan. 27 in JAMA Dermatology.

Abstract
Full Text (subscription or payment may be required)

Tysabri Impacts Seroconversion in John Cunningham Virus

THURSDAY, Jan. 28, 2016 (HealthDay News) -- For patients with John Cunningham virus (JCV), natalizumab (Tysabri) treatment affects seroconversion and JCV index values, according to a study published online Jan. 27 in Neurology: Neuroimmunology & Neuroinflammation.

Abstract
Full Text
Editorial

Clipping Nodes Improves Pathologic Evaluation

THURSDAY, Jan. 28, 2016 (HealthDay News) -- Clipping nodes with biopsy-confirmed metastatic disease improves pathologic evaluation among patients with breast cancer, according to a study published online Jan. 25 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

~1% of Physicians Account for One-Third of Malpractice Claims

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- A small number of physicians account for a considerable proportion of all paid malpractice claims, according to a study published in the Jan. 28 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)

Guidance Issued for Infants With Suspected Zika Infection

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Interim guidelines have been developed for the evaluation and testing of infants born to mothers who traveled to or resided in an area with Zika virus transmission during pregnancy. The guidelines were published in the Jan. 26 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Specific Trichoscopic Findings Linked to Tinea Capitis

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Specific trichoscopic findings are associated with tinea capitis (TC), according to a research letter published online Jan. 22 in the British Journal of Dermatology.

Abstract
Full Text (subscription or payment may be required)

Too Few Nurses Compliant With Standard Precautions

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Fewer than 20 percent of nurses report compliance with all nine Standard Precautions (SP), although adherence is the most effective means of preventing bloodborne pathogen transmission, according to a study published in the Jan. 1 issue of the American Journal of Infection Control.

Abstract
Full Text

Clinical Significance of Varying Degrees of Neutropenia Explored

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Neutropenia is associated with viral infections and hematological malignancies in a dose-dependent manner, according to a study published online Jan. 21 in the Journal of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)

Extended Elevated Recurrence Rates for ER-Positive Breast CA

WEDNESDAY, Jan. 27, 2016 (HealthDay News) -- Breast cancer patients with estrogen receptor (ER)-positive disease have elevated annualized hazards of recurrence during extended follow-up, according to a study published online Jan. 18 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Possibility for Health Care Legislation Changes in 2016

TUESDAY, Jan. 26, 2016 (HealthDay News) -- Given the current political climate and issues of bipartisan concern, 2016 could see certain changes to health care legislation, according to a report published in Medical Economics.

More Information

Consistent CRC Detection Seen for Fecal Immunochemical Tests

TUESDAY, Jan. 26, 2016 (HealthDay News) -- Fecal immunochemical tests (FITs) can consistently detect colorectal cancer when used on an annual basis, and they are effective even in the second, third, and fourth years of screening, according to a study published online Jan. 26 in the Annals of Internal Medicine.

Full Text (subscription or payment may be required)

Prednisolone Therapy Induces Procoagulant State

TUESDAY, Jan. 26, 2016 (HealthDay News) -- For healthy subjects, 10 days of prednisolone therapy induces a procoagulant state, according to a study published online Jan. 21 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

ACP Presents High-Value Care Advice for Hematuria

TUESDAY, Jan. 26, 2016 (HealthDay News) -- In a clinical guideline published online Jan. 26 in the Annals of Internal Medicine, recommendations relating to evaluation of hematuria are presented for clinicians.

Full Text

About 1 in 7 Colorectal Cancer Patients Younger Than 50

MONDAY, Jan. 25, 2016 (HealthDay News) -- Nearly one in seven colorectal cancer patients are under 50, and younger patients are more likely to have advanced-stage cancer, according to a report published online Jan. 25 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Hypoglycemia, Atherosclerosis Progression Link Explored

MONDAY, Jan. 25, 2016 (HealthDay News) -- In the Veterans Affairs Diabetes Trial, hypoglycemia was associated with coronary artery calcium (CAC) progression only in the standard therapy group (versus intensive therapy), according to research published online Jan. 19 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Estrogen Metabolism May Have an Impact on Stroke Recovery

MONDAY, Jan. 25, 2016 (HealthDay News) -- 2-methoxyestradiol (2-ME), an endogenous metabolite of estradiol, inhibits proliferation, pro-inflammatory responses, and phagocytosis in microglia, according to a study published online Jan. 5 in the American Journal of Physiology-Endocrinology and Metabolism.

Abstract
Full Text

Research Suggests Broader Role for HPV in HNSCC Etiology

MONDAY, Jan. 25, 2016 (HealthDay News) -- Human papillomavirus (HPV)-16 detection is tied to incidence of oropharyngeal squamous cell carcinoma (SCC); and other HPVs, including γ11- and γ12-HPV species and β1-HPV-5 type, are also associated with head and neck squamous cell carcinoma (HNSCC), according to a study published online Jan. 21 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Only Severe Preeclampsia Linked to Antiβ2GP1 Immunoglobulin G

MONDAY, Jan. 25, 2016 (HealthDay News) -- Severe preeclampsia (S-PEecl), but not non-severe preeclampsia (NS-PEecl), is associated with antiβ2GP1 immunoglobulin (Ig)G, according to a study published online Jan. 18 in the Journal of Thrombosis and Haemostasis.

Abstract
Full Text (subscription or payment may be required)

ACOG Supports CDC's Zika Virus Travel Precautions

FRIDAY, Jan. 22, 2016 (HealthDay News) -- The American College of Obstetricians and Gynecologists (ACOG) has issued a statement and practice advisory in support of new guidelines aimed at shielding pregnant women from the mosquito-borne Zika virus.

More Information - ACOG
More Information - CDC

CDC: Increasing Rate of Gastroschisis Seen in U.S.

FRIDAY, Jan. 22, 2016 (HealthDay News) -- The birth defect gastroschisis among U.S. infants has increased over the past 18 years, according to research published in the Jan. 22 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

Many Seniors Getting Unneeded Mammography, PSA Screens

FRIDAY, Jan. 22, 2016 (HealthDay News) -- Many older Americans are unnecessarily screened for breast and prostate cancer, according to a research letter published online Jan. 21 in JAMA Oncology.

Full Text (subscription or payment may be required)

Pediatric Nasopharyngeal CA Has Different Patient Demographic

FRIDAY, Jan. 22, 2016 (HealthDay News) -- Pediatric patients with nasopharyngeal carcinoma (NPC) are more often black and present with stage IV disease, but they have lower mortality than adult patients, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract
Full Text (subscription or payment may be required)

Curcumin Cuts Acetaminophen-Induced Hepatotoxicity in Mice

FRIDAY, Jan. 22, 2016 (HealthDay News) -- Curcumin can attenuate acetaminophen-induced mitochondrial alterations in the livers of mice, according to an experimental study published online Jan. 15 in the Journal of Pharmacy and Pharmacology.

Abstract
Full Text (subscription or payment may be required)

Inhibition of mTOR Restores Corticosteroid Sensitivity in COPD

FRIDAY, Jan. 22, 2016 (HealthDay News) -- Inhibition of mammalian target of rapamycin (mTOR) by rapamycin restores corticosteroid sensitivity in patients with chronic obstructive pulmonary disease (COPD), according to a study published in the Jan. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Blood Test May Help Predict Acute Myeloid Leukemia Return

THURSDAY, Jan. 21, 2016 (HealthDay News) -- A simple blood test may be an inexpensive, easy, and effective way to predict risk of recurrence of a common form of acute myeloid leukemia (AML), characterized by a mutation in the NPM1 gene, according to research published in the Jan. 21 issue of the New England Journal of Medicine.

Abstract
Full Text
Editorial

Blood Test May Help Guide Appropriateness of Antibiotic Rx

THURSDAY, Jan. 21, 2016 (HealthDay News) -- Researchers say they're closer to developing a blood test that distinguishes between viral and bacterial respiratory infections. The findings are published in the Jan. 20 issue of Science Translational Medicine.

Full Text (subscription or payment may be required)

Opt-Out Testing in the ER May Boost HIV Testing Rates

THURSDAY, Jan. 21, 2016 (HealthDay News) -- "Opt-out" testing could significantly increase the number of patients who agree to be tested for HIV, according to research published online Jan. 19 in The BMJ.

Full Text
Editorial

Pregnancy Ups Metastasis, Recurrence, Death in Melanoma

THURSDAY, Jan. 21, 2016 (HealthDay News) -- Women diagnosed with melanoma during or just after pregnancy are at greater risk from the cancer than other women, according to a study published online Jan. 20 in the Journal of the American Academy of Dermatology.

Abstract
Full Text (subscription or payment may be required)

CDX2-Negative Colon Cancer May Need More Tx Post Surgery

THURSDAY, Jan. 21, 2016 (HealthDay News) -- Colon tumors that don't produce the protein CDX2 are more likely to recur following surgical removal in patients with stage II colon cancer, according to study findings published in the Jan. 21 issue of the New England Journal of Medicine.

Abstract
Full Text
Editorial

Mutations in TUBB8 Linked to Form of Female Infertility

THURSDAY, Jan. 21, 2016 (HealthDay News) -- For a small number of women with a rare form of infertility, mutations in a particular gene may be the cause, according to a study published in the Jan. 21 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Depressive Symptoms Linked to Coronary Artery Calcium

THURSDAY, Jan. 21, 2016 (HealthDay News) -- Depressive symptoms seem to be associated with coronary artery calcium (CAC) in older men and women, according to a study published in the Feb. 1 issue of The American Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

Anesthesia After 40 Not Linked to Mild Cognitive Impairment

WEDNESDAY, Jan. 20, 2016 (HealthDay News) -- Receiving general anesthesia for surgery after age 40 doesn't appear to raise the risk for mild cognitive impairment later in life, according to a study published online Jan. 20 in the Mayo Clinic Proceedings.

Abstract
Full Text

Antipsychotic-Exposed Youths Have Increased T2DM Risk

WEDNESDAY, Jan. 20, 2016 (HealthDay News) -- Youths treated with antipsychotics have increased cumulative risk and exposure-adjusted incidence of type 2 diabetes mellitus (T2DM), according to research published online Jan. 20 in JAMA Psychiatry.

Abstract
Full Text

Fluorescence Visualization-Guided Sx Efficacious in Oral CA

WEDNESDAY, Jan. 20, 2016 (HealthDay News) -- For patients with oral cancer, fluorescence visualization (FV)-guided surgery is associated with a reduction in local recurrence, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract
Full Text

Physicians Choose Less Aggressive Care at End of Life

TUESDAY, Jan. 19, 2016 (HealthDay News) -- Physicians facing death are less likely to demand aggressive care, according to two research letters published in the Jan. 19 issue of the Journal of the American Medical Association, a theme issue on death, dying, and end of life.

Full Text 1 (subscription or payment may be required)
Full Text 2 (subscription or payment may be required)

CDC: HIV Testing Rates Still Low Among Teens, Young Adults

TUESDAY, Jan. 19, 2016 (HealthDay News) -- An estimated 50 percent of young Americans infected with HIV don't know they have it, according to research published online Jan. 19 in Pediatrics.

Full Text (subscription or payment may be required)

CDC: Distribution of Lyme Disease Vectors Has Expanded

TUESDAY, Jan. 19, 2016 (HealthDay News) -- Ticks that transmit Lyme disease are now found in nearly half of all counties in the United States, a much broader swath than was seen in the late 1990s, according to research published online Jan. 18 in the Journal of Medical Entomology.

Full Text

KRAS, BRAF V600E Mutations Impact Survival in Colon Cancer

MONDAY, Jan. 18, 2016 (HealthDay News) -- For patients with stage III colon cancer treated with leucovorin, fluorouracil, and oxaliplatin (FOLFOX), KRAS and BRAF V600E mutations are associated with worse clinical outcome in patients with microsatellite-stable tumors, according to a study published online Jan. 14 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Earlier AMD Onset With Rare Genetic Variants

MONDAY, Jan. 18, 2016 (HealthDay News) -- Patients with age-related macular degeneration (AMD) carrying rare variants have earlier age at symptom onset and a higher prevalence of positive family history than noncarriers, according to a study published online Jan. 14 in JAMA Ophthalmology.

Abstract
Full Text (subscription or payment may be required)

Greater Transparency Being Promoted in Research

MONDAY, Jan. 18, 2016 (HealthDay News) -- Greater transparency is being promoted in clinical research, according to a health policy brief published online Jan. 14 in Health Affairs.

Full Text

FDA Approves Newly Designed Olympus Endoscope

MONDAY, Jan. 18, 2016 (HealthDay News) -- A newly designed Olympus duodenoscope was approved Friday by the U.S. Food and Drug Administration.

More Information

Guidelines Presented for Primary Adrenal Insufficiency

MONDAY, Jan. 18, 2016 (HealthDay News) -- Recommendations have been developed to address the diagnosis and treatment of primary adrenal insufficiency. The new clinical practical guidelines were published online Jan. 13 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
Full Text

Foreign-Born Students in U.S. Have Higher Case Rate of TB

MONDAY, Jan. 18, 2016 (HealthDay News) -- Foreign-born students in the United States have a higher case rate of tuberculosis (TB) than other foreign-born individuals, according to a study published online Jan. 5 in the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

Pertussis Outbreak Described in Preschool in Tallahassee

MONDAY, Jan. 18, 2016 (HealthDay News) -- A report published online Jan. 13 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases highlights a 2013 pertussis outbreak among mainly vaccinated preschool-aged children.

Full Text

Mortality Up With Low Bicarb Levels in Healthy Seniors

FRIDAY, Jan. 15, 2016 (HealthDay News) -- Seniors who are healthy but have low blood levels of bicarbonate are at higher risk for premature death, according to a study published online Jan. 14 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

Nitrate Intake Linked to Primary Open-Angle Glaucoma Risk

FRIDAY, Jan. 15, 2016 (HealthDay News) -- Higher dietary nitrate and green leafy vegetable intake is associated with reduced risk of primary open-angle glaucoma (POAG), according to a study published online Jan. 14 in JAMA Ophthalmology.

Abstract
Full Text

Prophylactic Antibiotic Choice Impacts Post-Hysterectomy SSI

FRIDAY, Jan. 15, 2016 (HealthDay News) -- For women undergoing hysterectomy, prophylactic antibiotic choice impacts the risk of surgical site infection rates, according to a study published in the February issue of Obstetrics & Gynecology.

Full Text (subscription or payment may be required)

Geographic Variation in HPV Oropharyngeal Cancer Prevalence

FRIDAY, Jan. 15, 2016 (HealthDay News) -- There is geographic variation in the proportion of head and neck cancers attributable to human papillomavirus (HPV), according to a study published online Jan. 8 in Head & Neck.

Abstract
Full Text

Diabetes Mellitus Is Independent Risk Factor for A-Fib

FRIDAY, Jan. 15, 2016 (HealthDay News) -- Within a general population from China, diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF), with the correlation persisting after adjustment for cardiovascular risk factors, according to a study published online Jan. 8 in the Journal of Diabetes Investigation.

Abstract
Full Text

WHO: West Africa Ebola Outbreak Is Over

THURSDAY, Jan. 14, 2016 (HealthDay News) -- The two-year Ebola outbreak in West Africa that claimed more than 11,300 lives is over, the World Health Organization said Thursday.

More Information

Scope-Related Infections Higher Than Previously Thought

THURSDAY, Jan. 14, 2016 (HealthDay News) -- More patients than previously estimated contracted life-threatening infections from contaminated medical scopes in recent years, according to a U.S. Senate committee report released Wednesday.

Health Highlights: Jan. 14, 2016

Zika Virus Concerns May Curb Travel for Pregnant Women

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Pregnant women in the United States may be warned against traveling to Latin American and Caribbean countries where mosquitoes are spreading a virus that may cause brain damage in newborns.

More Information

Lower Risk of Parkinson's With Higher Urate Concentration

THURSDAY, Jan. 14, 2016 (HealthDay News) -- For men, but not women, the risk of developing Parkinson's disease (PD) is lower with higher plasma urate concentrations, according to a study published online Jan. 13 in Neurology.

Abstract
Full Text (subscription or payment may be required)

Geographic Factors Impact HPV Vaccine Initiation in Teen Girls

THURSDAY, Jan. 14, 2016 (HealthDay News) -- Initiation of human papillomavirus (HPV) vaccination is highest among teen girls in poorer communities and in populations that are mainly Hispanic or mixed race, according to a study published online Jan. 14 in Cancer, Epidemiology, Biomarkers & Prevention.

Abstract
Full Text

Tickborne Bacteria Identified in Ticks from Texas

THURSDAY, Jan. 14, 2016 (HealthDay News) -- About 23 percent of ticks from Texas carry bacterial DNA from at least one of the following: Rickettsia, Borrelia, and Ehrlichia spp., according to a report published online Jan. 13 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

Full Text

New Blood Test May Improve Tracking of Advanced Melanoma

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- A new blood test might improve doctors' ability to track the spread of advanced melanoma, according to results of a small, preliminary study published in the January issue of Molecular Oncology.

Full Text (subscription or payment may be required)

Incidence of Radiation-Induced Breast Cancer Examined

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- There is variability in radiation-induced breast cancer incidence and mortality associated with digital mammography screening, according to a study published online Jan. 12 in the Annals of Internal Medicine.

Full Text

Stem Cell Sources Used for HSCT Vary by Country, Resources

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Use of bone marrow as the stem cell source for hematopoietic stem cell transplantation (HSCT) increases with increasing incomes, according to a research letter published in the Jan. 12 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required)

PPARγ Antagonist Imatinib Improves Insulin Sensitivity

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Imatinib (Gleevec) blocks CDK5-mediated peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation as an antagonist ligand, improving insulin sensitivity and promoting browning of white adipose tissue, according to a study published online Jan. 6 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Allergic Rhinitis Constitutes Considerable Burden

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Allergic rhinitis (AR) constitutes a considerable burden, with patients at increased risk for asthma and various mental health comorbidities, according to a study published online Jan. 8 in Allergy.

Abstract
Full Text (subscription or payment may be required)

Acute Ozone Exposure Ups Stress Hormone in Humans

WEDNESDAY, Jan. 13, 2016 (HealthDay News) -- Acute ozone exposure increases stress hormones and causes alterations in peripheral lipid metabolism in humans, according to research published online Jan. 8 in the American Journal of Respiratory and Critical Care Medicine.

Full Text (subscription or payment may be required)

Frozen Samples Comparable to Fresh in Fecal Transplant

TUESDAY, Jan. 12, 2016 (HealthDay News) -- Frozen stool samples work just as well as freshly donated samples when treating Clostridium difficile infection through fecal transplantation, according to findings published in the Jan. 12 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Nivolumab, Contact Immunotx Treats In-Transit Melanoma

TUESDAY, Jan. 12, 2016 (HealthDay News) -- Nivolumab in combination with contact immunotherapy can successfully treat in-transit melanoma, according to two case reports published online Dec. 12 in the Journal of Dermatology.

Abstract
Full Text (subscription or payment may be required)

False-Positive Mammography Results Are Common

TUESDAY, Jan. 12, 2016 (HealthDay News) -- For women undergoing digital mammography screening, false-positive results are common, especially among younger women and those with risk factors, according to research published online Jan. 12 in the Annals of Internal Medicine.

Full Text

Researchers ID Three New Glaucoma-Related Genes

TUESDAY, Jan. 12, 2016 (HealthDay News) -- Three newly identified genes associated with primary open angle glaucoma bring the total number of such genes to 15, according to a study published online Jan. 11 in Nature Genetics.

Abstract
Full Text (subscription or payment may be required)

Even Small Decline in Kidney Function Tied to CVD Risk

TUESDAY, Jan. 12, 2016 (HealthDay News) -- Even a slight decline in kidney function can potentially lead to heart damage, according to research published online Jan. 11 in Hypertension.

Abstract
Full Text

USPSTF Recommends Biennial Screening Mammography

MONDAY, Jan. 11, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends biennial screening mammography for women aged 50 to 74 years. These findings form the basis of a final recommendation statement published online Dec. 12 in the Annals of Internal Medicine.

Full Text
Editorial 1
Editorial 2

Excessive Hair Growth Documented After IFN-β Tx

MONDAY, Jan. 11, 2016 (HealthDay News) -- Excessive hair growth can occur after local administration of interferon (IFN)-β treatment for malignant melanoma, according to a letter to the editor published online Dec. 12 in the Journal of Dermatology.

Full Text (subscription or payment may be required)

Measure of Outpatient Colonoscopy Quality Developed

MONDAY, Jan. 11, 2016 (HealthDay News) -- A risk-adjusted measure of outpatient colonoscopy quality can help inform patient choices and assist in quality-improvement efforts, according to research published in the January issue of Gastroenterology.

Abstract
Full Text

Prevalence of Folate Deficiency 14.1 Percent in Multiple Myeloma

MONDAY, Jan. 11, 2016 (HealthDay News) -- The prevalence of folate deficiency is 14.1 percent among patients with multiple myeloma (MM), according to a letter to the editor published online Dec. 19 in the International Journal of Laboratory Hematology.

Abstract
Full Text (subscription or payment may be required)

Breast Implants Linked to Chronic Pulmonary Silicone Embolism

MONDAY, Jan. 11, 2016 (HealthDay News) -- Chronic pulmonary silicone embolism related to saline breast implants has been detailed in a letter to the editor published in the January issue of the Annals of the American Thoracic Society.

Full Text (subscription or payment may be required)

Reduction in Proximal, Distal Leg Muscle Strength in T2DM

MONDAY, Jan. 11, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), proximal and distal leg muscle strength is reduced, and proximal but not distal muscle volume is also reduced, according to a study published online Jan. 6 in Diabetes Care.

Abstract
Full Text (subscription or payment may be required)

Cardiomyopathy Etiology Impacts Catheter Ablation Outcomes

FRIDAY, Jan. 8, 2016 (HealthDay News) -- For patients with atrial fibrillation (AF) and left ventricular systolic dysfunction, cardiomyopathy etiology impacts long term outcomes of catheter ablation, according to a study published online Dec. 28 in the Journal of Cardiovascular Electrophysiology.

Abstract
Full Text (subscription or payment may be required)

Truncating Variant Prevalence Up in Peripartum Cardiomyopathy

FRIDAY, Jan. 8, 2016 (HealthDay News) -- Women with peripartum cardiomyopathy have a prevalence of truncating variants similar to that seen in patients with dilated cardiomyopathy, according to a study published online Jan. 6 in the New England Journal of Medicine.

Abstract
Full Text

CDC: TB Potentially Passed From Zoo Elephants to People

FRIDAY, Jan. 8, 2016 (HealthDay News) -- Transmission of tuberculosis from infected captive elephants to humans may be possible with long-term, close contact with the animals, according to research published in the Jan. 8 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text

U.S. Cancer Mortality Rates Down 23 Percent Since 1991

THURSDAY, Jan. 7, 2016 (HealthDay News) -- Since peaking in 1991, cancer mortality rates in the United States have dropped by 23 percent, according to findings included in Cancer Statistics, 2016, the American Cancer Society's latest annual report on cancer incidence, mortality, and survival. The report was published online Jan. 7 in CA: A Cancer Journal for Clinicians.

Abstract
Full Text

Trio of Papers Reveal Lessons Learned From Ebola Epidemic

THURSDAY, Jan. 7, 2016 (HealthDay News) -- A trio of papers published in the Jan. 7 issue of the New England Journal of Medicine reveal some of what has been learned about the Ebola virus.

Full Text 1
Full Text 2
Full Text 3

Blood Test May Help Rule Out Preeclampsia in Short Term

THURSDAY, Jan. 7, 2016 (HealthDay News) -- A sFlt-1:PlGF ratio of 38 or lower appears to help rule out preeclampsia in women in whom the syndrome is suspected clinically, according to a study published in the Jan. 7 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Antibody Tx Reduces Graft-vs-Host Post Stem Cell Transplant

THURSDAY, Jan. 7, 2016 (HealthDay News) -- Antibody therapy before stem cell transplant may benefit patients with acute leukemia, according to research published in the Jan. 7 issue of the New England Journal of Medicine.

Full Text

Dietary Glutamic Acid Linked to Lower Risk of Colorectal Cancer

THURSDAY, Jan. 7, 2016 (HealthDay News) -- Dietary glutamic acid intake is associated with reduced risk of developing colorectal cancer (CRC), according to a study published online Dec. 30 in Cancer.

Abstract
Full Text (subscription or payment may be required)

African-American Men Produce Less Prostate-Specific Antigen

THURSDAY, Jan. 7, 2016 (HealthDay News) -- Among men with Gleason score 3+3=6 prostate cancer, African-Americans produce less prostate-specific antigen than Caucasians, according to a study published in the February issue of The Journal of Urology.

Abstract
Full Text (subscription or payment may be required)

Role of Pathogenic Variants in Arrhythmia Genes Unclear

WEDNESDAY, Jan. 6, 2016 (HealthDay News) -- Potentially pathogenic genetic variants in arrhythmia susceptibility genes are not associated with an abnormal phenotype, according to a study published in the Jan. 5 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Early-Life Exercise May Promote Lifelong Brain Function

WEDNESDAY, Jan. 6, 2016 (HealthDay News) -- Early-life exercise-induced alterations in gut microbiota may promote brain function and emotional well-being, according to a study published online Dec. 9 in Immunology & Cell Biology.

Full Text (subscription or payment may be required)

Novel Antigen Implicated in Immediate Hypersensitivity to Beer

WEDNESDAY, Jan. 6, 2016 (HealthDay News) -- A novel antigen, which belongs to the protein Z family, may be involved in immediate hypersensitivity to beer, according to a case report published online Dec. 12 in the Journal of Dermatology.

Abstract
Full Text (subscription or payment may be required)

Inherited Mutations in 18 Percent With Ovarian Cancer

WEDNESDAY, Jan. 6, 2016 (HealthDay News) -- Pathogenic germline mutations are common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC), according to a study published online Dec. 30 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Pesticide in Milk Years Ago May Be Linked to Signs of Parkinson's

TUESDAY, Jan. 5, 2016 (HealthDay News) -- Men who drank milk that may have been tainted with a pesticide when they were young might be more likely to develop signs of Parkinson's disease, according to a study published online Dec. 9 in Neurology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Researchers Calculate Family Risk Estimates for Cancer

TUESDAY, Jan. 5, 2016 (HealthDay News) -- Having an identical twin diagnosed with cancer increases the other twin's risk of developing not just that type but any form of cancer, according to research published in the Jan. 5 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)

Signs of CTE in Brain of Deceased 25-Year-Old Football Player

TUESDAY, Jan. 5, 2016 (HealthDay News) -- A case report published online Jan. 4 in JAMA Neurology highlights a neuropsychological test profile conducted on a patient with chronic traumatic encephalopathy (CTE).

Full Text
Editorial (subscription or payment may be required)

Axillary pCR Linked to Improved Breast Cancer Survival

TUESDAY, Jan. 5, 2016 (HealthDay News) -- For women with breast cancer treated with primary systemic chemotherapy (PST), achieving axillary pathologic complete response (pCR) is associated with improved survival, according to a study published online Dec. 30 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Support for First-Line Erlotinib in NSCLC With EGFR Mutations

MONDAY, Jan. 4, 2016 (HealthDay News) -- For patients with non-small-cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations, erlotinib is active, and treatment beyond progression is feasible and may delay salvage therapy in selected patients, according to a study published online Dec. 30 in JAMA Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Diagnostic Factors May Help Patients Avoid Prostate Biopsy

MONDAY, Jan. 4, 2016 (HealthDay News) -- Initial diagnostic characteristics may be able to identify men initiating active surveillance who could avoid confirmatory biopsy, according to a study published in the January issue of The Journal of Urology.

Abstract
Full Text
Editorial (subscription or payment may be required)

β-Genus Human Papillomavirus Poses Skin Cancer Risk

MONDAY, Jan. 4, 2016 (HealthDay News) -- β-genus human papillomavirus (β-HPV) is a risk factor for cutaneous squamous cell carcinoma (cSCC) in otherwise healthy individuals, according to a review published online Dec. 30 in JAMA Dermatology.

Abstract
Full Text (subscription or payment may be required)

CDC: Heart Failure Mortality Up 2012 Through 2014

MONDAY, Jan. 4, 2016 (HealthDay News) -- The age-adjusted mortality rates from heart failure decreased from 2000 to 2012 but increased from 2012 through 2014, according to a December data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

More Information

Physician's Briefing

HealthDay

HealthDay is the world’s largest syndicator of health news and content, and providers of custom health/medical content.

Consumer Health News

A health news feed, reviewing the latest and most topical health stories.

Professional News

A news feed for Health Care Professionals (HCPs), reviewing latest medical research and approvals.