Here are what the editors at HealthDay consider to be the most important developments in Pathology for July 2013. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Anemia Linked to Elevated Dementia Risk in Older Adults
WEDNESDAY, July 31 (HealthDay News) -- Anemia is associated with an increased risk of developing dementia in older adults, according to a study published online July 31 in Neurology.
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HIV-Associated Lymphoma Characterized As Heterogeneous
WEDNESDAY, July 31 (HealthDay News) -- HIV-associated lymphoma is highly heterogeneous in the current treatment era, but mortality has remained steady, according to a study published online July 26 in the Journal of the National Cancer Institute.
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Surgery Not Needed With All Abnormal Breast Lesions
WEDNESDAY, July 31 (HealthDay News) -- Women with atypical lobular hyperplasia (ALH) or lobular carcinoma in situ (LCIS) biopsy findings can be safely observed when careful radiologic-pathologic correlation for concordance is established, according to research published online July 30 in Radiology.
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Health 'Mutual Accountability' Pilot Program Launching
WEDNESDAY, July 31 (HealthDay News) -- The State of Oklahoma Office of Management and Enterprise Services has chosen MedEncentive to conduct a three-year heath improvement program pilot among HealthChoice beneficiaries.
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Bisphenol-A Has Detrimental Effects on Oocytes
WEDNESDAY, July 31 (HealthDay News) -- Exposure of oocytes to bisphenol-A (BPA) has detrimental effects on cell growth and increases oocyte degeneration and spontaneous activation, according to a study published online July 30 in Human Reproduction.
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Glucose Intolerance Not Linked to Alzheimer's Pathology
TUESDAY, July 30 (HealthDay News) -- There seems to be no significant correlation between glucose intolerance and insulin resistance with brain β-amyloid burden or Alzheimer's disease (AD) pathology, according to a study published online July 29 in JAMA Neurology.
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Reversal of Medical Practices Common Over Past Decade
TUESDAY, July 30 (HealthDay News) -- Over 100 contemporary medical practices have subsequently been reversed over the last 10 years, according to a review published online July 22 in Mayo Clinical Proceedings.
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Review Explores HPV Link to Higher Risk of Esophageal Cancer
TUESDAY, July 30 (HealthDay News) -- The presence of human papillomavirus (HPV) DNA is associated with a three-fold higher risk of esophageal cancer, according to a study published online July 24 in PLOS ONE.
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Aids Help Decision Making for Prostate Cancer Screening
TUESDAY, July 30 (HealthDay News) -- A print and web-based decision aid helps men with their decision making about prostate cancer screening, but does not affect screening rates, according to a study published online July 29 in JAMA Internal Medicine.
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Genetic Risk Score Linked to Increased Risk of Diabetes
MONDAY, July 29 (HealthDay News) -- A genetic risk score based on 46 gene variants linked to type 2 diabetes is associated with increases in the risk of type 2 diabetes and declines in glucose control and beta-cell function, according to a study published online July 8 in Diabetes.
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Benzene Proximity Linked to Increased Lymphoma Risk
MONDAY, July 29 (HealthDay News) -- Proximity to benzene release sites in metropolitan areas of Georgia are associated with an increased risk of non-Hodgkin's lymphoma, according to a study published online July 29 in Cancer.
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Histopathology Not Needed With Tympanomastoidectomy
MONDAY, July 29 (HealthDay News) -- The clinical utility of histopathologic evaluation of cholesteatoma cysts is low in patients undergoing tympanomastoidectomy for chronic otitis media, according to research published online July 9 in The Laryngoscope.
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High H. pylori Cure Rate for Nonbismuth Quadruple Tx
MONDAY, July 29 (HealthDay News) -- Optimized nonbismuth quadruple regimens, either hybrid or concomitant, have a cure rate of more than 90 percent for Helicobacter pylori (H. pylori) infections, according to a study published in the July issue of Gastroenterology.
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No Change in HPV Vaccine Coverage for Teen Girls in 2012
MONDAY, July 29 (HealthDay News) -- In 2012 there was little increase in human papillomavirus (HPV) vaccination among teenage girls, according to a report published in the July 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
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Automated EHRs Improve Immunization Reporting
FRIDAY, July 26 (HealthDay News) -- Automated public health reporting of immunization data via electronic health records (EHRs) significantly improves timeliness of reporting, according to a study published in Applied Clinical Informatics.
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FDA: New Test Detects TB and Antibiotic Resistance
FRIDAY, July 26 (HealthDay News) -- A new test to detect bacteria that cause tuberculosis (TB) and simultaneously determine if the bacteria are resistant to the antibiotic rifampin has been approved by the U.S. Food and Drug Administration.
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Oxytocin Regulates Reward-Driven Food Intake
FRIDAY, July 26 (HealthDay News) -- In addition to its role in social bonding, oxytocin regulates reward-driven food intake in people, according to a study published online July 8 in Diabetes.
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Review Explores Link Between Family History and Cancer Risk
FRIDAY, July 26 (HealthDay News) -- A review of family cancer histories indicates that several potential cancer syndromes exist among close relatives, possibly indicating the presence of genetic factors influencing multiple cancer sites, according to research published online July 24 in the Annals of Oncology.
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Prenatal Mercury Exposure, ASD Behaviors Not Linked
THURSDAY, July 25 (HealthDay News) -- Prenatal exposure to methlymercury is not associated with autism spectrum disorder (ASD) phenotypic behaviors, according to a study published online July 18 in Epidemiology.
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CDC: U.S. Patients Suffering Tropical Infection
THURSDAY, July 25 (HealthDay News) -- The intestinal infection cyclosporiasis is generally seen in people living or traveling in tropical or subtropical areas, but two cases brought to the attention of the U.S. Centers of Disease Control and Prevention in June occurred in individuals who had not been traveling internationally at the time infection would have occurred.
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IOM Confirms Geographic Variation in Health Spending
THURSDAY, July 25 (HealthDay News) -- Considerable geographic variation exists in health care spending and utilization, but a geographically-based value index is unlikely to promote value improvement, according to a report published July 24 by the Institute of Medicine.
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Breast CA Nodal Mets More Common With Certain Mutations
THURSDAY, July 25 (HealthDay News) -- Lymph node metastases are more common in breast cancers with mutations in a cellular signaling pathway associated with growth, according to a study published online July 24 in JAMA Surgery.
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Screening Mammogram Recall Rates Vary by Practice Site
THURSDAY, July 25 (HealthDay News) -- Patient population factors likely contribute to higher mammogram recall rates at an academic hospital site versus a community office practice employing the same radiologists, according to a study published in online July 24 in Radiology.
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Docs Need to Follow Patients' Lead, Embrace Social Media
WEDNESDAY, July 24 (HealthDay News) -- As more patients discuss and manage their health care online, doctors need to keep up and use social media, according to a report published by the American Medical Association (AMA).
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U.S. Physicians Not Supportive of Changes in Payment Models
TUESDAY, July 23 (HealthDay News) -- U.S. physicians accept some responsibility for reducing health care costs in their practice, but most do not want to change payment models, according to research published in the July 24/31 issue of the Journal of the American Medical Association.
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Breast Cancer Survival for Blacks Unchanged Since 1991
TUESDAY, July 23 (HealthDay News) -- Breast cancer survival for black women diagnosed in the last two decades has not changed, and appears to be lower than breast cancer survival for white women due to presentation characteristics at diagnosis rather than treatment differences, according to a study published in the July 24/31 issue of the Journal of the American Medical Association.
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Pros and Cons of Electronic Cigarette Regulation Discussed
TUESDAY, July 23 (HealthDay News) -- The pros and cons of electronic cigarette (EC) regulation are discussed in to two editorials published online July 23 in The Lancet Respiratory Medicine.
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Tick Vector of Heartland Virus Identified
TUESDAY, July 23 (HealthDay News) -- The tick Amblyomma americanum has been identified as the vector of the heartland virus (HRTV), the first pathogenic Phlebovirus (Family: Bunyaviridae), according to a study published online July 22 in the American Journal of Tropical Medicine and Hygiene.
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Premiums Expected to Be About 20 Percent Lower in 2014
MONDAY, July 22 (HealthDay News) -- Premiums in the Health Insurance Marketplace are likely to be about 20 percent lower than anticipated in 2014, according to a report published by the U.S. Department of Health and Human Services (HHS).
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Tablets Help Physicians Keep Up With Medical Research
MONDAY, July 22 (HealthDay News) -- Most physicians find keeping up with the latest research to be challenging, but the use of tablets and smartphones may help, according to a report published by Wolters Kluwer Health.
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Self-Referrals for Anatomic Pathology Services Very Costly
FRIDAY, July 19 (HealthDay News) -- Health care providers who self-refer for anatomic pathology services cost Medicare about $69 million in 2010, according to a report published by the U.S. Government Accountability Office (GAO).
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Household Chemicals Influence Thyroid Function
FRIDAY, July 19 (HealthDay News) -- Serum concentrations of perfluorinated chemicals (PFCs), which have been widely used in various household products for years, are linked with changes in thyroid hormone levels in women and men, according to research published online July 17 in the Journal of Clinical Endocrinology & Metabolism.
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Top Challenges for Docs Include Financial Management
FRIDAY, July 19 (HealthDay News) -- The top issues and challenges facing physicians include managing changing reimbursement models with payors and financial management, according to a report published by Wolters Kluwer Health.
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Missed Diagnoses, Med Errors Most Common Malpractice Claims
FRIDAY, July 19 (HealthDay News) -- The most common medical misadventures resulting in malpractice claims in primary care are missed or delayed diagnoses and medication errors, according to a review published online July 18 in BMJ Open.
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Closer Look at the H7N9 Virus Reveals New Details
FRIDAY, July 19 (HealthDay News) -- The influenza virus H7N9 isolated from poultry and humans can bind human airway receptors and can transmit between ferrets by respiratory droplets, according to research published online July 18 in Science.
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Intelligent Knife IDs Tumor Biochemistry During Resection
THURSDAY, July 18 (HealthDay News) -- For patients undergoing tumor resection, the coupling of rapid evaporative ionization mass spectrometry (REIMS) with electrosurgery, an approach known as the intelligent knife (iKnife), has been validated as an intraoperative approach to accurately identify tissue, according to a study published in the July 17 issue of Science Translational Medicine.
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Mutation ID'd in Some With Kidney, Urinary Tract Disorders
WEDNESDAY, July 17 (HealthDay News) -- Independent mutations have been identified in the dual serine-threonine and tyrosine protein kinase gene (DSTYK) in 2.3 percent of patients with congenital abnormalities of the kidney and urinary tract, according to a study published online July 17 in the New England Journal of Medicine.
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Financial Incentives Can Drive Health IT Adoption
WEDNESDAY, July 17 (HealthDay News) -- Financial incentives can drive providers' adoption of health information technology, including e-prescribing, according to a study published in the July issue of Health Affairs.
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Redesign of Medical Education Needed for Chronic Disease Era
TUESDAY, July 16 (HealthDay News) -- Medical education programs should be redesigned to address the current complex chronic disease era, with emphasis on appropriate basic sciences and clinical skills, according to a special communication published online July 15 in JAMA Internal Medicine.
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Acid Reflux Medications May Constrict Blood Vessels
TUESDAY, July 16 (HealthDay News) -- The mechanism by which proton pump inhibitors (PPIs) increase the risk of major adverse cardiovascular events may now be better understood, according to a study published online July 3 in Circulation.
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CMS Medicare Physician Fee Schedule Could Benefit Docs
TUESDAY, July 16 (HealthDay News) -- The Centers for Medicare and Medicaid Services has released the 2014 proposed Medicare physician fee schedule, which could help create a more equitable payment system by adjusting misvalued codes and proposing new complex management codes, according to a report published by American Academy of Family Physicians.
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More Job Opportunities Available for Physicians
MONDAY, July 15 (HealthDay News) -- More than half of physicians are receiving up to three employment solicitations per week, according to a report published by American Medical Association (AMA).
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Liver Failure Via Acetaminophen OD Tied to Worse Outcomes
MONDAY, July 15 (HealthDay News) -- Long-term survivors of acute liver failure report lower quality of life compared with the general population, while survivors of acetaminophen overdose report the lowest quality of life, possibly due to psychiatric and substance abuse disorders, according to a study published online June 18 in Liver Transplantation.
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EHRs May Slow Growth in Ambulatory Health Care Costs
MONDAY, July 15 (HealthDay News) -- Adoption of electronic health records (EHRs) modestly slows growth in ambulatory health care costs, according to research published in the July 16 issue of the Annals of Internal Medicine.
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CMS Proposes New Rule for Outpatient Payment Policies
MONDAY, July 15 (HealthDay News) -- A new rule proposes updating Medicare payment policies and rates for the hospital outpatient prospective payment system (OPPS) and ambulatory surgical center (ASC) services, according to a report issued by the Centers for Medicare and Medicaid Services.
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Index CRC Tumor Site Impacts Increased CA Risk for Survivors
MONDAY, July 15 (HealthDay News) -- The location of index colorectal cancer (CRC) affects the incidence of second cancer after CRC, according to a study published online July 15 in Cancer.
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Omega-3 Fatty Acids Linked to Risk of Prostate Cancer
FRIDAY, July 12 (HealthDay News) -- High blood concentrations of long-chain omega-3 polyunsaturated fatty acids (PUFA) are linked to an increased risk of prostate cancer, according to research published online July 10 in the Journal of the National Cancer Institute.
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Physicians Frustrated by Third-Party Interference
FRIDAY, July 12 (HealthDay News) -- Third-party interference is the most commonly cited key frustration for physicians, according to the results of a survey published in Physicians Practice.
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AMA Offers Guidance for Improving EHR Effectiveness
FRIDAY, July 12 (HealthDay News) -- The American Medical Association (AMA) House of Delegates has voted for policies to help physicians navigate patient interaction while using electronic devices and to improve the interoperability of electronic health records (EHRs).
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Men Still Want PSA Testing Despite Guidance, Risks
FRIDAY, July 12 (HealthDay News) -- The October 2011 U.S. Preventive Services Task Force (USPSTF) recommendation advising against prostate-specific antigen (PSA) testing may be met with resistance by men, according to a study published online July 9 in the American Journal of Preventive Medicine.
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Grants of $150 Million for Community Health Centers
THURSDAY, July 11 (HealthDay News) -- Grants totaling $150 million are to be shared by 1,100 community health centers to help enroll patients in insurance programs, according to the U.S. Department of Health and Human Services (HHS).
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Health Searches May Be Leaked to Third Parties
THURSDAY, July 11 (HealthDay News) -- Free health-related websites often have third-party tracking elements and leak search terms to third-party tracking entities, unlike U.S. government or physician-oriented websites, according to a research letter published online July 8 in JAMA Internal Medicine.
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U.S. Adults Value Health Care Provider Skill Evaluation
THURSDAY, July 11 (HealthDay News) -- Most adults feel that health care providers who treat them should adhere to a recertification program, including passing examinations, attending educational programs, and undergoing certification, regardless of time in practice, according to a report published by the National Board of Certification and Recertification for Nurse Anesthetists (NBCRNA) and the Citizen Advocacy Center.
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Ob-Gyns Stray From Guidelines for Cervical Cancer Prevention
THURSDAY, July 11 (HealthDay News) -- A survey of obstetrician-gynecologists has identified barriers to the adoption of human papillomavirus (HPV) vaccination and screening measures for cervical cancer, according to research published online July 9 in the American Journal of Preventive Medicine.
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One in Five U.S. Adults Will Have Trouble Paying Medical Bills
THURSDAY, July 11 (HealthDay News) -- About one in five U.S. adults will have problems paying health care bills in 2013, including about 10 million adults with year-round insurance coverage, according to a report published by the American Medical Association (AMA).
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Red Cross Issues Emergency Call for Blood Donors
THURSDAY, July 11 (HealthDay News) -- The American Red Cross has issued an emergency request for blood and platelet donors of all blood types, according to report posted July 9.
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In 2010, Blood Transfusion Most Frequent Hospital Procedure
THURSDAY, July 11 (HealthDay News) -- The most frequent procedure performed during hospitalization in 2010 was blood transfusion, which was common among all age groups except for infants, according to the Agency for Healthcare Research and Quality (AHRQ).
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Quality Metrics Play Small Role in Physician Compensation
THURSDAY, July 11 (HealthDay News) -- Quality measures play a small but emerging role in physician compensation, according to a report published by the Medical Group Management Association (MGMA).
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Prevalence of Oral HPV Infection Low in Healthy Men
WEDNESDAY, July 10 (HealthDay News) -- Newly acquired oral infections with oncogenic human papilloma virus (HPV) are rare, and infections typically clear within a year, according to a study published online July 2 in The Lancet.
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Artificial Sweeteners Linked to Cardiometabolic Disease Risk
WEDNESDAY, July 10 (HealthDay News) -- The role of artificial sweeteners is potentially problematic, with consumption of artificially sweetened beverages (ASBs) associated with increased risks of cardiometabolic diseases, according to a study published online July 10 in Trends in Endocrinology & Metabolism.
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Inverse Relationship for Cancer, Alzheimer's Dementia
WEDNESDAY, July 10 (HealthDay News) -- There seems to be an inverse relationship in the incidence of cancer and Alzheimer's disease (AD) dementia, with a reduced risk of cancer for those with AD dementia, and vice versa, according to a study published online July 10 in Neurology.
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Existing Medicaid Patients May Miss Out on Preventive Care
WEDNESDAY, July 10 (HealthDay News) -- Existing Medicaid enrollees may not receive preventive care measures the Affordable Care Act mandates for those covered under new insurance requirements, according to a study published in the July issue of Health Affairs.
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Health Insurance Marketplaces Not Required to Verify Claims
WEDNESDAY, July 10 (HealthDay News) -- Health insurance marketplaces will not be required to verify consumers' income and health insurance status and can rely on self-reported information, the Obama administration announced Friday.
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Tablets More Useful Than Smartphones for Docs Using EHRs
WEDNESDAY, July 10 (HealthDay News) -- Although tablets are less often used by physicians than smartphones, they are more frequently used for accessing electronic health records (EHRs), and time spent on tablets is much higher, according to two reports published by AmericanEHR Partners.
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Improvements Noted in U.S. Health From 1990 to 2010
WEDNESDAY, July 10 (HealthDay News) -- From 1990 to 2010, considerable progress has been made in improving health in the United States, according to a report published online July 10 in the Journal of the American Medical Association.
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Digital Divide Plagues Underserved Areas
TUESDAY, July 9 (HealthDay News) -- Electronic health record (EHR) adoption is uneven, with traditionally underserved areas having lower adoption rates across the United States, according to a study published online June 26 in Health Services Research.
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GI Involvement Linked to Relapse of Vasculitis in Kids
TUESDAY, July 9 (HealthDay News) -- In the largest single-center study of polyarteritis nodosa (PAN) in childhood, fever, myalgia, and skin involvement were found to be the most common symptoms, and cumulative dose of cyclophosphamide was associated with lower risk of relapse, while gastrointestinal (GI) involvement was linked to increased relapse risk. The study has been published online June 10 in Arthritis & Rheumatism.
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Adoption of Electronic Health Records Is Progressing
TUESDAY, July 9 (HealthDay News) -- In 2012, 44 percent of hospitals reported having at least a basic electronic health record (EHR), according to an annual report published by the Robert Wood Johnson Foundation.
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Black Men Less Likely to Have Advanced Neoplasia at Screening
MONDAY, July 8 (HealthDay News) -- Although blacks are more likely than whites to be diagnosed with and die from colorectal cancer, black men are less likely to have advanced colorectal neoplasia (ACN) at screening, according to a study published in the July 2 issue of the Annals of Internal Medicine.
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Middle East Coronavirus Does Not Have Pandemic Potential
MONDAY, July 8 (HealthDay News) -- The new Middle East respiratory syndrome coronavirus (MERS-CoV) does not yet have pandemic potential, according to a study published online July 5 in The Lancet.
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Practices Are Not Ready for Implementation of ICD-10
MONDAY, July 8 (HealthDay News) -- Most practices are not ready for implementation of the International Classification of Diseases, Tenth Revision (ICD-10), according to a report published by the Medical Group Management Association (MGMA).
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Adding 'Organ Donor' to Facebook Ups Registration
FRIDAY, July 5 (HealthDay News) -- Initiation of the Facebook organ donor initiative has dramatically increased organ donor registration, according to a study published online June 18 in the American Journal of Transplantation.
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Decrease in Beach Closing/Advisory Days in 2012
THURSDAY, July 4 (HealthDay News) -- There was a 14 percent decrease from 2011 to 2012 in the number of beach closing and advisory days, according to a report from Natural Resources Defense Council (NRDC).
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Melanoma Recurrence a Decade Later Not Rare
WEDNESDAY, July 3 (HealthDay News) -- Melanoma that recurs over a decade after initial treatment is not uncommon, occurring in about 7 percent of patients, and is associated with improved survival compared with that seen in patients whose tumors recur earlier, according to a study published in the July issue of the Journal of the American College of Surgeons.
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Three-Gene mRNA Signature IDs Acute Cellular Rejection
WEDNESDAY, July 3 (HealthDay News) -- A signature composed of messenger RNA (mRNA) from three genes in urinary cells can identify kidney biopsy samples showing acute cellular rejection, according to a study published in the July 4 issue of the New England Journal of Medicine.
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Ice Pops Can Cause False-Positive Galactomannan Test
WEDNESDAY, July 3 (HealthDay News) -- A case of a false-positive serum aspergillus antigen (galactomannan) test in a patient who underwent a stem-cell transplant and ate flavored ice pops is described in a letter published in the July 4 issue of the New England Journal of Medicine.
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More Than 40 Percent of Docs Report Work Dissatisfaction
WEDNESDAY, July 3 (HealthDay News) -- Many physicians are dissatisfied and are unlikely to recommend the medical profession to young people, according to a report published by Jackson Healthcare.
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Short-Term UV Radiation Linked to Odds of Juvenile Myositis
WEDNESDAY, July 3 (HealthDay News) -- Short-term ultraviolet radiation (UVR) exposure may contribute to the development of juvenile myositis, according to a study published in the July issue of Arthritis & Rheumatism.
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Obama Administration: ACA's Employer Mandate Delayed
WEDNESDAY, July 3 (HealthDay News) -- The Obama Administration is postponing a major Affordable Care Act (ACA) provision, the employer mandate, according to an announcement made Tuesday via the U.S. Department of the Treasury website.
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New Tickborne Illness Identified in Northeastern U.S.
TUESDAY, July 2 (HealthDay News) -- Tick-exposed patients who present with acute febrile illness but have delayed response to doxycycline therapy or negative confirmatory test results for human granulocytic anaplasmosis (HGA) should be analyzed for evidence of infection with the newly recognized spirochete Borrelia miyamotoi, according to a case report published in the July 2 issue of the Annals of Internal Medicine.
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Kidney Involvement, High Anti-dsDNA Predict Lupus Flares
TUESDAY, July 2 (HealthDay News) -- Kidney involvement and high anti-double stranded (ds) DNA are independent predictors of moderate-severe lupus flare, according to research published online June 10 in Arthritis & Rheumatism.
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Docs Impact Comparative Effectiveness Research Opinion
TUESDAY, July 2 (HealthDay News) -- Doctors' support of comparative effectiveness research (CER) influences public opinion and has a greater impact on public opinion than cues from political players, according to research to be published this fall in the Journal of Health Politics, Policy and Law.
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