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March 2016 Briefing - Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for March 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Genetic Factors Associated With Cannabis Dependence Identified

THURSDAY, March 31, 2016 (HealthDay News) -- Specific cannabis dependence risk alleles have been identified, according to a study published online March 30 in JAMA Psychiatry.

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Stillbirth Less Likely for Women Receiving Trivalent Flu Vaccine

THURSDAY, March 31, 2016 (HealthDay News) -- Women receiving trivalent influenza vaccination are less likely to experience a stillbirth, especially for births occurring just after influenza season, according to a study published online March 30 in Clinical Infectious Diseases.

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Neuronal Heparan Sulfates Play Role in Amyloid Pathology

THURSDAY, March 31, 2016 (HealthDay News) -- Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in the March 30 issue of Science Translational Medicine.

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Long-Acting Raltegravir Shows Promise in Protection from HIV

THURSDAY, March 31, 2016 (HealthDay News) -- A long-acting formulation of the integrase inhibitor raltegravir can protect humanized bone marrow-liver-thymus (BLT) mice from high-dose vaginal HIV challenges, according to an experimental study published online March 21 in the Journal of Antimicrobial Chemotherapy.

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Gene Transfer Explored As Way to Up LV Function in Heart Failure

WEDNESDAY, March 30, 2016 (HealthDay News) -- Intracoronary delivery of adenovirus 5 encoding adenylyl cyclase 6 (Ad5.hAC6) is safe for patients with heart failure and reduced ejection fraction (EF), according to a study published online March 30 in JAMA Cardiology.

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Entry Receptor for Zika Virus Identified in Brain, Retina

WEDNESDAY, March 30, 2016 (HealthDay News) -- The candidate viral entry receptor for Zika virus, AXL, is highly expressed by cells in the developing human cortex and retina, according to an experimental study published online March 30 in Cell Stem Cell.

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Elevated Carcinoembryonic Antigen Described in Anorexia

WEDNESDAY, March 30, 2016 (HealthDay News) -- In a case report published online March 25 in the International Journal of Eating Disorders, elevated serum carcinoembryonic antigen (CEA) levels are observed in a male patient with anorexia nervosa (AN).

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Higher Weight in First Year May Up Risk of Islet Autoimmunity

WEDNESDAY, March 30, 2016 (HealthDay News) -- Development of islet autoimmunity and multiple islet autoantibodies appears to be related to weight z-scores at age 12 months, according to a study published online March 23 in Diabetes.

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Local Allergic Rhinitis Responds to Allergen Immunotherapy

TUESDAY, March 29, 2016 (HealthDay News) -- Dermatophagoides pteronyssinus (DP) subcutaneous allergen immunotherapy (AIT) seems safe and effective for local allergic rhinitis (LAR), according to a study published online March 23 in Allergy.

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How Can We Fix the Wage Gap Among Female Physicians?

MONDAY, March 28, 2016 (HealthDay News) -- Women doctors can address the gender wage disparity by understanding the reasons why they earn less, according to a report published in Medical Economics.

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2011 Criteria Facilitate Diagnosis of Long QT Syndrome

MONDAY, March 28, 2016 (HealthDay News) -- The 2011 criteria improve diagnosis of long QT syndrome (LQTS), according to a study published online March 23 in JACC: Clinical Electrophysiology.

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Only Conservative Strategy Makes PSA Cost-Effective

MONDAY, March 28, 2016 (HealthDay News) -- Highly conservative use of the prostate-specific antigen (PSA) test and biopsy referral is necessary for PSA screening to be cost-effective, according to a study published online March 24 in JAMA Oncology.

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Delayed Diagnosis of Acromegaly Reported in Elderly Woman

MONDAY, March 28, 2016 (HealthDay News) -- In a letter to the editor published in the March issue of the Journal of the American Geriatrics Society, delayed diagnosis of acromegaly is described in an elderly woman who initially presented with cutis verticis gyrata (CVG).

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Growth Differentiation Factor 15 Levels Linked to CAD

FRIDAY, March 25, 2016 (HealthDay News) -- Serum growth differentiation factor 15 (GDF-15) levels are associated with coronary artery disease (CAD), according to a study published online March 21 in Cardiovascular Therapeutics.

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Atrial Natriuretic Peptide IDs Left Atrial Reverse Remodeling

FRIDAY, March 25, 2016 (HealthDay News) -- Preprocedural serum atrial natriuretic peptide (ANP) levels predict left atrial reverse remodeling after catheter ablation in patients with atrial fibrillation (AF), according to a study published online March 23 in JACC: Clinical Electrophysiology.

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Low-Normal Sodium Deemed Major Risk for Mortality in Elderly

FRIDAY, March 25, 2016 (HealthDay News) - A slightly lower serum sodium concentration within the normal range is a major risk factor for mortality in elderly adults, according to a study published in the March issue of the Journal of the American Geriatrics Society.

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Retinal Ganglion Cells Derived From Pluripotent Stem Cells

FRIDAY, March 25, 2016 (HealthDay News) -- Stepwise differentiation through an enriched retinal progenitor intermediary facilitates the accomplishment of deriving retinal ganglion cells (RGCs) from human pluripotent stem cells (hPSCs), according to research published online March 21 in STEM CELLS.

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CDC: Tuberculosis Decline in the United States Has Hit a Plateau

THURSDAY, March 24, 2016 (HealthDay News) -- Two decades of progress toward eliminating tuberculosis (TB) in the United States has stalled, with incidence of the disease holding steady from 2013 to 2015, according to a report published in the March 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report in conjunction with World TB Day.

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Genome Sequencing IDs Time of Zika's Arrival in the Americas

THURSDAY, March 24, 2016 (HealthDay News) -- The Zika virus likely arrived in the Americas between May and December 2013, more than a year before it was first reported in Brazil, according to a study published online March 24 in Science.

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β-Carotene, Lycopene Prevent Dermatitis in Murine Model

THURSDAY, March 24, 2016 (HealthDay News) -- Oral administration of β-carotene or lycopene prevents atopic dermatitis (AD)-like dermatitis in HR-1 hairless mice, according to an experimental study published online March 19 in the Journal of Dermatology.

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Geographic Variation in Heart Disease Mortality Over Time

THURSDAY, March 24, 2016 (HealthDay News) -- From 1973-1974 to 2009-2010 there were changes in the geographic patterns of heart disease mortality, according to a study published in the March 22 issue of Circulation.

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Report of Bone Marrow/Liver Pathology Caused by Syphilis

WEDNESDAY, March 23, 2016 (HealthDay News) -- A case of acquired syphilis leading to involvement of the bone marrow and liver is described in a report published online March 22 in the Annals of Internal Medicine.

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PCSK9 Monoclonal Antibodies Show Promise in ACS

WEDNESDAY, March 23, 2016 (HealthDay News) -- Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies may represent a promising treatment option for acute coronary syndrome (ACS), according to a review published online March 22 in the Annals of Internal Medicine.

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BPA Alternative, Bisphenol S, Can Induce Fat Cell Formation

WEDNESDAY, March 23, 2016 (HealthDay News) -- Bisphenol S (BPS) induces adipogenesis in primary human preadipocytes, according to a study published online March 22 in Endocrinology.

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Endogenous Endophthalmitis ID'd After Breast Implant Surgery

TUESDAY, March 22, 2016 (HealthDay News) -- In a case report published online March 17 in JAMA Ophthalmology, bilateral endogenous endophthalmitis with chorioretinal involvement due to Candida albicans a few hours after breast augmentation surgery has been documented.

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Wrestling Wins for Most High School Athletic Skin Infections

TUESDAY, March 22, 2016 (HealthDay News) -- Among U.S. high school athletes, the rate of skin infections is 2.27 per 100,000 athlete exposures, with the majority occurring in wrestlers, according to a study published in the April issue of the Journal of the American Academy of Dermatology.

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MODY1 Form of Diabetes May Require Alternate Treatment

TUESDAY, March 22, 2016 (HealthDay News) -- Patients with maturity-onset diabetes of the young 1 (MODY1) are often misdiagnosed as having type 2 diabetes, but patients with MODY1 might benefit from therapies that target a specific pathway that appears to be essential to the function of insulin-secreting cells, according to an experimental study published online Jan. 20 in the Journal of Biological Chemistry.

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Low Likelihood for Atypia, DCIS Verification With Single Slide

TUESDAY, March 22, 2016 (HealthDay News) -- Interpretation of a single breast biopsy slide per case predicts low likelihood of verification for diagnosis of atypia or ductal carcinoma in situ (DCIS), according to a study published online March 22 in the Annals of Internal Medicine.

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Risk of Parkinson's Disease Increased for Rosacea Patients

MONDAY, March 21, 2016 (HealthDay News) -- Rosacea is associated with an increased risk for Parkinson's disease, according to research published online March 21 in JAMA Neurology.

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FDA: Most Powdered Medical Gloves Should Be Banned in U.S.

MONDAY, March 21, 2016 (HealthDay News) -- The U.S. Food and Drug Administration wants to ban most powdered medical gloves, saying they pose serious health risks to patients and health care providers alike.

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Worse Prognosis for Heart Failure Patients With Low Osmolality

MONDAY, March 21, 2016 (HealthDay News) -- For patients with heart failure and reduced ejection fraction, low osmolality at discharge is associated with worse all-cause mortality and readmission, according to research published in the April 1 issue of The American Journal of Cardiology.

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Poor Prognosis for Women With Pregnancy-Associated Melanoma

MONDAY, March 21, 2016 (HealthDay News) -- For women aged younger than 50 years, melanoma prognosis is worse for those aged 40 to 49 years and for those diagnosed with a pregnancy-associated melanoma, according to a study published in the April issue of the Journal of the American Academy of Dermatology.

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Genotype Doesn't Predict A-Fib in Hypertrophic Cardiomyopathy

MONDAY, March 21, 2016 (HealthDay News) -- For patients with hypertrophic cardiomyopathy (HC), genotype does not predict onset or severity of atrial fibrillation (AF), according to a study published in the April 1 issue of The American Journal of Cardiology.

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Exercise Prevents Diet-Induced Cell Senescence in Adipose Tissue

MONDAY, March 21, 2016 (HealthDay News) -- A novel mechanism has been proposed for the role of exercise in mitigating the detrimental impact of a fast-food diet (FFD) in mice, via prevention of cellular senescence, according to an experimental study published March 16 in Diabetes.

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CDC: 116 Travel-Associated Zika Cases in U.S. So Far This Year

FRIDAY, March 18, 2016 (HealthDay News) -- During the first two months of this year, 116 U.S. residents have tested positive for infection with the Zika virus, and all but one were linked to travel to regions endemic for the virus. The findings were reported in the March 18 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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MTHFR Polymorphism, Higher Homocysteine Up Cataract Risk

FRIDAY, March 18, 2016 (HealthDay News) -- Methylenetetrahydrofolate reductase (MTHFR) polymorphism and elevated homocysteine levels contribute to the risk of cortical cataract, separately and together, according to a study published online March 17 in JAMA Ophthalmology.

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Case Report: Ceftriaxone-Linked Renal Toxicity in Adult Male

FRIDAY, March 18, 2016 (HealthDay News) -- A case of ceftriaxone-associated renal toxicity in an adult has been documented in a case report published online Feb. 23 in the Journal of Clinical Pharmacy and Therapeutics.

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Case Before Supreme Court May Expose Doctors to Large Fines

FRIDAY, March 18, 2016 (HealthDay News) -- A case before a state supreme court could potentially expose physicians to large fines based on a legal technicality relating to what they should have known, rather than what they knew, according to the American Medical Association (AMA).

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Duration of Estrogen Deficiency Linked to Fibrosis Risk in NAFLD

FRIDAY, March 18, 2016 (HealthDay News) -- For postmenopausal women with nonalcoholic fatty liver disease (NAFLD), longer duration of estrogen deficiency is associated with increased odds of having more severe fibrosis, according to a study published online Feb. 26 in Hepatology.

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Drop in S. aureus Carriage Rate With Antibiotic Tx of Acne

FRIDAY, March 18, 2016 (HealthDay News) -- Treatment of acne with antibiotics is associated with a significant decrease in the rate of Staphylococcus aureus carriage, according to a study published in the April issue of the Journal of the American Academy of Dermatology.

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Highest Diabetes Prevalence in Poorest Countries

FRIDAY, March 18, 2016 (HealthDay News) -- Diabetes prevalence is highest in poorer countries, even after adjustment for traditional risk factors, according to a study published online March 10 in Diabetes Care.

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Rate of Transmission of Clostridium difficile Quantified

FRIDAY, March 18, 2016 (HealthDay News) -- Hospitalized patients with Clostridium difficile infection (CDI) transmit C. difficile at a much higher rate than that of asymptomatic carriers and community sources, according to a report published in the April issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Predictions Made for Zika Arrival in U.S. Cities This Summer

THURSDAY, March 17, 2016 (HealthDay News) -- Some major U.S. cities, including New York City and Los Angeles, could face outbreaks of the Zika virus this summer, according to a report published online March 16 in PLOS Currents: Outbreaks.

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Non-HIV-Related Kaposi Sarcoma in BRAFi-Treated Patient

THURSDAY, March 17, 2016 (HealthDay News) -- In a case report published online Feb. 28 in the Journal of Clinical Pharmacy and Therapeutics, researchers document non-HIV-associated Kaposi sarcoma in a male patient with myasthenia gravis and metastatic melanoma treated with the BRAF inhibitor dabrafenib.

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SCD Accounts for >30 Percent of CV Deaths After NSTE ACS

THURSDAY, March 17, 2016 (HealthDay News) -- Sudden cardiac death (SCD) accounts for more than 30 percent of cardiovascular deaths after non-ST segment elevation acute coronary syndrome (NSTE ACS), according to research published online March 16 in JAMA Cardiology.

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Many Cases of MERS-CoV Are Health Care-Associated

THURSDAY, March 17, 2016 (HealthDay News) -- Middle East respiratory syndrome coronavirus (MERS CoV) infections are frequently associated with health care settings, according to a report published in the April issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Spending on Prescription Meds Up About 5 Percent in 2015

THURSDAY, March 17, 2016 (HealthDay News) -- Spending on prescription medications for insured Americans increased about 5 percent in 2015, with the increase half of that seen in 2014, the Associated Press reported.

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Antibiotic Resistance in Pediatric UTIs Up Globally

WEDNESDAY, March 16, 2016 (HealthDay News) -- Many children who develop urinary tract infections (UTIs) tied to the Escherichia coli bacteria are now failing to respond to antibiotic treatment, according to research published online March 15 in The BMJ.

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CDC: Obesity Contributing to Hike in Asthma Rates Among Women

WEDNESDAY, March 16, 2016 (HealthDay News) -- As weight rises, so too does the risk for asthma, according to a March data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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DNA Methylation in Adulthood Linked to Season of Birth

WEDNESDAY, March 16, 2016 (HealthDay News) -- DNA methylation in adulthood is associated with season of birth and may influence the effect of season of birth on allergy, according to a study published online March 12 in Allergy.

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Disruptive Patients Distract Docs, May Receive Compromised Care

WEDNESDAY, March 16, 2016 (HealthDay News) -- Disruptive patients may get worse care from physicians, according to a study published online March 7 in BMJ Quality & Safety. The findings aren't definitive because the researchers tested how physicians responded in fictional vignettes, instead of real-life encounters. Still, the results suggest that such patients distract physicians from doing their jobs.

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Distal Symmetric Polyneuropathy Linked to MetS Components

WEDNESDAY, March 16, 2016 (HealthDay News) -- Distal symmetric polyneuropathy (DSP) prevalence increases with an increasing number of components of metabolic syndrome, according to a study published online March 10 in Diabetes Care.

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HIV-Seropositive CIN3+ Patients Have Lower HPV16 Prevalence

TUESDAY, March 15, 2016 (HealthDay News) -- HIV-seropositive women with cervical intraepithelial neoplasia (CIN) grade ≥3 (CIN3+) are less likely to have human papillomavirus (HPV) 16, according to a study published in the March issue of the American Journal of Obstetrics & Gynecology.

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Familial Hypercholesterolemia More Common Than Thought

TUESDAY, March 15, 2016 (HealthDay News) -- Familial hypercholesterolemia affects about one in every 250 American men and women and significantly increases their risk for an early heart attack, according to a study published in the March 15 issue of Circulation.

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Mayo Clinic Has Established Model to Help Battle Burnout

TUESDAY, March 15, 2016 (HealthDay News) -- In an effort to reduce burnout among physicians, the Mayo Clinic is initiating a model to raise camaraderie and increase collaboration, according to a report published by the American Medical Association (AMA).

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Serotonin Directly Implicated in Rheumatoid Arthritis

MONDAY, March 14, 2016 (HealthDay News) -- Serotonin appears to be involved in autoimmune arthritis through Th17 immunity and bone resorption, according to an experimental study published online March 8 in The American Journal of Pathology.

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FDA Gives Tentative Approval to Tests of Gene-Modified Mosquitos

MONDAY, March 14, 2016 (HealthDay News) -- U.S. health officials on Friday gave tentative approval to a field test in the Florida Keys of mosquitoes genetically modified to help curb the spread of the Zika virus.

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Diabetes Patients More Susceptible to Staph Bacteremia

FRIDAY, March 11, 2016 (HealthDay News) -- Patients with diabetes may be significantly more likely to develop community-acquired Staphylococcus aureus bacteremia (CA-SAB) than those without diabetes, according to a study published online March 10 in the European Journal of Endocrinology.

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CYP3A7*1C Allele Linked to Cancer Mortality, Progression

FRIDAY, March 11, 2016 (HealthDay News) -- The CYP3A7*1C allele appears to be associated with mortality and disease progression in specific cancers, according to a study published online March 10 in Cancer Research.

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Evidence Links Agent Orange to Bladder Cancer, Hypothyroidism

FRIDAY, March 11, 2016 (HealthDay News) -- There is stronger evidence of a link between the herbicide Agent Orange and bladder cancer and hypothyroidism among U.S. military personnel exposed to the chemical during the Vietnam War, a new Institute of Medicine report shows.

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Allergen Components ID Latex-Induced Occupational Asthma

FRIDAY, March 11, 2016 (HealthDay News) -- High levels of specific immunoglobulin E (sIgE) reactivity to recombinant Hevea brasiliensis (rHev b) can diagnose natural rubber latex (NRL) allergy, according to a study published online March 4 in Allergy.

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CDC: Zika Poses Serious Threat to Puerto Rico

THURSDAY, March 10, 2016 (HealthDay News) -- U.S. health officials issued an assessment Thursday of the continued spread of the Zika virus, which is already suspected of causing thousands of birth defects in Brazil and has made inroads into Puerto Rico.

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Survival Benefit for Kidneys From Incompatible Living Donors

THURSDAY, March 10, 2016 (HealthDay News) -- In what researchers are calling a possible "paradigm shift," a new study shows kidney disease patients may live longer if they receive a transplant from an incompatible living donor rather than wait for a good match. The research was published in the March 10 issue of the New England Journal of Medicine.

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Zika Now Tied to Meningoencephalitis

THURSDAY, March 10, 2016 (HealthDay News) -- The list of neurological disorders potentially associated with the Zika virus continues to grow, according to a letter to the editor and a perspective piece published online March 9 in the New England Journal of Medicine.

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Treating Infant Cataracts With Endogenous Stem Cells Feasible

THURSDAY, March 10, 2016 (HealthDay News) -- A new surgical technique for removing cataracts might allow the eye's stem cells to regenerate a healthy lens, according to preliminary findings reported online March 9 in Nature.

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CDC: U.S. Cancer Mortality Rate Continues to Fall

WEDNESDAY, March 9, 2016 (HealthDay News) -- Overall rates of cancer and cancer mortality in the United States continue to decline, according to the Annual Report to the Nation on the Status of Cancer, a yearly report issued by the American Cancer Society, the U.S. Centers for Disease Control and Prevention, the National Cancer Institute, and the North American Association of Central Cancer Registries. The report was published online March 9 in Cancer.

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Physicians' Contracts Can Affect Patients, Professionalism

WEDNESDAY, March 9, 2016 (HealthDay News) -- Problematic clauses in physicians' contracts can impact patient care and professionalism, according to an Ideas and Opinions piece published online March 8 in the Annals of Internal Medicine.

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Research Offers Clues to Impact of Lupus on Immune System

TUESDAY, March 8, 2016 (HealthDay News) -- Scientists have gained new insight into systemic lupus erythematosus (SLE) which they hope will lead to new therapies, or help guide current treatment choices. The research was published online March 8 in Immunity.

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Cold Exposure, Capsinoids Further Beige Adipocyte Biogenesis

TUESDAY, March 8, 2016 (HealthDay News) -- A molecular circuit has been identified that controls beige adipocyte biogenesis, according to research published online March 2 in Diabetes.

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High Neutrophil to Lymphocyte Ratio Prognostic in Breast Cancer

TUESDAY, March 8, 2016 (HealthDay News) -- Presurgery high neutrophil to lymphocyte ratio (NLR) is a prognostic variable of worse outcome in Caucasian patients with early breast cancer, according to a study published online March 7 in ESMO Open: Cancer Horizons.

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Maternal Vitamin D Deficiency May Up MS Risk in Offspring

TUESDAY, March 8, 2016 (HealthDay News) -- Maternal serum 25-hydroxyvitamin D (25[OH]D) deficiency in early pregnancy is associated with increased risk of multiple sclerosis (MS) in offspring, according to a study published online March 7 in JAMA Neurology.

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Low Testosterone Predicts Mortality in Advanced Liver Disease

TUESDAY, March 8, 2016 (HealthDay News) -- For men with advanced liver disease, sarcopenia and low testosterone predict mortality, with better prediction for low testosterone, according to a study published in the March issue of the Journal of Gastroenterology and Hepatology.

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Chemical Exposure Down With Switch in Cosmetics Among Teens

MONDAY, March 7, 2016 (HealthDay News) -- Switching to chemical-free cosmetics and shampoos quickly lowers levels of hormone-disrupting chemicals in the bodies of adolescent girls, according to a study published online March 7 in Environmental Health Perspectives.

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Dietary Glycemic Index Linked to Lung Cancer Risk

MONDAY, March 7, 2016 (HealthDay News) -- Dietary glycemic index (GI) is associated with lung cancer risk, according to a study published in the March issue of Cancer Epidemiology, Biomarkers & Prevention.

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Large Number of Mutations Needed to ID TB Drug Resistance

MONDAY, March 7, 2016 (HealthDay News) -- In order to determine Mycobacterium tuberculosis drug resistance, a large number of mutations are needed, according to a study published online Feb. 24 in the American Journal of Respiratory and Critical Care Medicine.

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Bloodstream Infection Outbreak in Wisconsin Linked to 18 Deaths

FRIDAY, March 4, 2016 (HealthDay News) -- The source of a bacterial bloodstream infection linked with the deaths of 18 people in Wisconsin is being sought by federal, state, and local health officials.

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Heavy Coffee Consumption May Lower Risk of Multiple Sclerosis

FRIDAY, March 4, 2016 (HealthDay News) -- Individuals who consume about six cups of coffee a day are almost one-third less likely to develop multiple sclerosis (MS) than non-drinkers, according to research published online March 3 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Scientists Report Insights Into Zika Virus and Microcephaly

FRIDAY, March 4, 2016 (HealthDay News) -- Laboratory studies have shown that Zika can infect a type of neural stem cell that gives rise to the cerebral cortex of the brain, according to research published online March 4 in Cell Stem Cell.

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CDC: Hospitals Making Progress Against Antibiotic Resistance

FRIDAY, March 4, 2016 (HealthDay News) -- Although U.S. hospitals are making gains in the fight against some antibiotic-resistant bacteria, too many patients are still affected in health care facilities, according to a new report from the U.S. Centers for Disease Control and Prevention.

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Daily Low-Dose Aspirin May Reduce Risk of Some Cancers

FRIDAY, March 4, 2016 (HealthDay News) -- Taking low-dose aspirin every day may lower the overall risk of cancer by 3 percent, mostly due to larger reductions seen in risk for colon and gastrointestinal tumors, according to research published online March 3 in JAMA Oncology.

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ACOG Issues Recommendations on Prenatal Screening

FRIDAY, March 4, 2016 (HealthDay News) -- Recommendations on screening for genetic disorders and fetal aneuploidy have been updated, according to two Practice Bulletins published online March 3 in Obstetrics & Gynecology.

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Location, Age Affect Hospital Visitor Hand Sanitizer Use

FRIDAY, March 4, 2016 (HealthDay News) -- Location, time of day, and age, as well as being in a group, are all associated with increased use of alcohol-based hand sanitizer (AHS) for hospital visitors, according to a study published in the March 1 issue of the American Journal of Infection Control.

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Mutations in ANGPTL4 Linked to Coronary Artery Disease

THURSDAY, March 3, 2016 (HealthDay News) -- Mutations in the angiopoietin-like 4 (ANGPTL4) gene are associated with coronary artery disease, according to two studies published online March 2 in the New England Journal of Medicine.

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Google Pledges $1 Million to Help Fight Zika Virus

THURSDAY, March 3, 2016 (HealthDay News) -- A $1 million donation to fight the spread of the Zika virus and an offer to help analyze data to predict the spread of the mosquito-borne disease was announced by Google.

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U.S. Bans E-Cigarettes on Commercial Flights

THURSDAY, March 3, 2016 (HealthDay News) -- Electronic cigarettes have been banned from commercial flights, the U.S. Department of Transportation announced Wednesday.

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Ovarian CA Encompasses More Than One Kind of Malignancy

THURSDAY, March 3, 2016 (HealthDay News) -- Ovarian cancer isn't a single disease, but rather a number of different malignancies involving the ovaries, an expert U.S. panel says.

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Decrease in Pediatric S. aureus Infections Due to MRSA

THURSDAY, March 3, 2016 (HealthDay News) -- The proportion of pediatric Staphylococcus aureus infections due to methicillin-resistant S. aureus seems to be decreasing in pediatric populations, according to a study published online March 1 in Pediatrics.

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High Mole Count Doesn't Always Indicate Higher Melanoma Risk

THURSDAY, March 3, 2016 (HealthDay News) -- Patients with melanoma often have few typical nevi (TN), and no atypical nevi (AN), according to a study published online March 2 in JAMA Dermatology.

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Red Ginseng, Vitamin C May Increase Immune Cell Activity

THURSDAY, March 3, 2016 (HealthDay News) -- Red ginseng and vitamin C enhance immune cell activation and suppress viral infection in mice, according to an experimental study published online Feb. 21 in the Journal of Pharmacy and Pharmacology.

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FDA: Guidance to Help Prevent Donor-Related Zika Infection

WEDNESDAY, March 2, 2016 (HealthDay News) -- The U.S. Food and Drug Administration has issued new guidance for reducing the potential transmission risk of Zika virus from human cells, tissues, and cellular and tissue-based products (HCT/Ps).

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SCOTUS: States Can't Force Health Care Data Release

WEDNESDAY, March 2, 2016 (HealthDay News) -- The Supreme Court has ruled against state efforts to collect health care data from insurance plans.

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Spouse Education Level May Impact Choice for Rural Practice

WEDNESDAY, March 2, 2016 (HealthDay News) -- Physicians who are married to a highly-educated spouse are less likely to work in rural underserved areas, according to a study published in the March 1 issue of the Journal of the American Medical Association.

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Type 1 Diabetes Linked to Increased Risk of Certain Cancers

WEDNESDAY, March 2, 2016 (HealthDay News) -- Individuals with type 1 diabetes appear to have a higher risk for cancers of the stomach, liver, pancreas, endometrium, ovary, and kidneys, but a reduced risk for prostate and breast cancers, according to research published online Feb. 29 in Diabetologia.

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Case of Hepatitis E Transmission Via Plasma Exchange

WEDNESDAY, March 2, 2016 (HealthDay News) -- A case of hepatitis E virus (HEV) infection has been reported in a kidney transplant recipient, according to a research letter published online March 1 in the Annals of Internal Medicine.

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Metabolic Syndrome Tied to Risk of Mild Cognitive Impairment

WEDNESDAY, March 2, 2016 (HealthDay News) -- The incidence of mild cognitive impairment (MCI) and MCI progression to dementia is increased in association with metabolic syndrome (MetS), according to a study published online Feb. 29 in JAMA Neurology.

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PRAME Predicts Metastasis in Class 1 Uveal Melanoma

WEDNESDAY, March 2, 2016 (HealthDay News) -- Preferentially expressed antigen in melanoma (PRAME) mRNA expression predicts metastasis in Class 1 uveal melanoma (UM), according to a study published in the March 1 issue of Clinical Cancer Research.

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Uric Acid Levels Low in Teens With Type 1 Diabetes

TUESDAY, March 1, 2016 (HealthDay News) -- Plasma uric acid (PUA) levels are significantly lower in adolescent patients with type 1 diabetes (T1D) than in healthy control subjects, and there does not appear to be a link between PUA levels and cardiorenal abnormalities in these patients, according to a study published online Feb. 19 in Diabetes Care.

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High Levels of Exercise May Be Cardiotoxic

TUESDAY, March 1, 2016 (HealthDay News) -- Emerging evidence suggests that there may be some cardiotoxicity associated with exercise, according to a review published online Feb. 24 in the Canadian Journal of Cardiology.

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Prostate Cancer Tied to Higher Colorectal Cancer Risk

TUESDAY, March 1, 2016 (HealthDay News) -- The risk of colorectal cancer is increased after a diagnosis of prostate cancer, according to a study published online Feb. 25 in Cancer.

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Zika Infection Linked to Guillain-Barré Syndrome

TUESDAY, March 1, 2016 (HealthDay News) -- Zika virus infection may be associated with incidence of Guillain-Barré syndrome, according to a study published online Feb. 29 in The Lancet.

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Many Do Not Share Personal Genetic Testing Results With PCP

TUESDAY, March 1, 2016 (HealthDay News) -- Many individuals who undergo direct-to-consumer (DTC) personal genomic testing (PGT) do not share the results with their primary care provider (PCP), according to research published online March 1 in the Annals of Internal Medicine.

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Physician's Briefing