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Flu Vaccine Found to Be Safe in Youngest Children

No serious adverse events in children aged 6 months to 23 months

TUESDAY, Oct. 24 (HealthDay News) -- The trivalent inactivated flu vaccine is safe for children aged 6 months to 23 months, with no serious adverse events, according to a large trial reported in the Oct. 25 issue of the Journal of the American Medical Association.

Simon J. Hambidge, M.D., Ph.D., of Kaiser Permanente Colorado in Denver, and colleagues examined the safety of the trivalent inactivated influenza vaccine in 45,356 children between 6 months and 23 months of age who received the vaccine between 1991 and 2003.

The researchers found there were no conditions that were significantly more likely to occur after vaccination. Thirteen illnesses were less likely to occur after vaccination, including upper respiratory tract infection and otitis media.

"In the largest population-based study to date of the safety of trivalent inactivated influenza vaccine in young children, there were very few medically attended events, none of which were serious, significantly associated with the vaccine," Hambidge and colleagues conclude.

Several authors report having received funding from, or been employed by, drug companies.

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