Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for January 2014. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Postmenopausal Hormone Rx May Cut Risk for Glaucoma
FRIDAY, Jan. 31, 2014 (HealthDay News) -- Use of estrogen-only postmenopausal hormone (PMH) treatment may help reduce the risk for primary open-angle glaucoma (POAG), according to research published online Jan. 30 in JAMA Ophthalmology.
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Aspirin Linked to Reduced Growth of Ear Tumors
FRIDAY, Jan. 31, 2014 (HealthDay News) -- Patients with sporadic vestibular schwannoma (sVS), which can cause hearing loss, are half as likely to have tumor growth if they take aspirin, according to research published in the February issue of Otology & Neurotology.
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AAP Approves Childhood Immunization Schedules for 2014
FRIDAY, Jan. 31, 2014 (HealthDay News) -- The recommended childhood and adolescent immunization schedules for 2014 have been approved, according to an American Academy of Pediatrics (AAP) policy statement published in the Feb. 1 issue of Pediatrics.
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Inappropriate Use of Antibiotics in ERs Remains High for Adults
THURSDAY, Jan. 30, 2014 (HealthDay News) -- For patients presenting to the emergency department with acute respiratory tract infections (ARTI), inappropriate utilization of antibiotics has decreased for children, but not for adults, according to a study published online Dec. 16 in Antimicrobial Agents and Chemotherapy.
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Androgen Deprivation Therapy Can Take Emotional Toll
THURSDAY, Jan. 30, 2014 (HealthDay News) -- Changes in mental and emotional well-being occur in prostate cancer patients on androgen deprivation therapy (ADT), according to research published in an upcoming issue of The Journal of Urology.
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Businesses Urge Change to ACA's Insurance Mandate
WEDNESDAY, Jan. 29, 2014 (HealthDay News) -- Beginning in 2015, U.S. businesses with 50 or more workers must provide health insurance to "full-time" employees, meaning workers who log at least 30 hours a week, on average.
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Handwashing Appears Best in Prevention of Common Cold
WEDNESDAY, Jan. 29, 2014 (HealthDay News) -- The evidence relating to prevention and treatment of the common cold is frequently poor, but best evidence for prevention supports physical methods such as handwashing and possibly use of zinc supplements, according to a review published online Jan. 27 in CMAJ, the journal of the Canadian Medical Association.
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ASA Issues Top Five Choosing Wisely Recommendations
WEDNESDAY, Jan. 29, 2014 (HealthDay News) -- The top five anesthesiology-related pain medicine issues that physicians and patients should question have been released by the American Society of Anesthesiologists (ASA) as part of the Choosing Wisely campaign.
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Insurance Eligibility Headaches Expected With ACA
TUESDAY, Jan. 28, 2014 (HealthDay News) -- With the influx of newly insured patients under the Affordable Care Act, physician practices should be prepared to spend even more time verifying coverage, according to an article published Jan. 2 in Medical Economics.
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Role of Vitamin D in Disease Prevention Is Uncertain
TUESDAY, Jan. 28, 2014 (HealthDay News) -- Supplementation with vitamin D to prevent disease does not appear to improve health outcomes, according to research published online Jan. 24 in The Lancet: Diabetes & Endocrinology.
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FDA Panel Considers First Pill for Ragweed Allergy
TUESDAY, Jan. 28, 2014 (HealthDay News) -- There may be good news coming in the form of a pill for the millions of Americans who suffer from ragweed allergy. On Tuesday, the U.S. Food and Drug Administration's Allergenic Products Advisory Committee will consider whether to recommend approval of the first pill to prevent this annual scourge.
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Hormone Therapy Linked to Reduced Arthroplasty Revision
MONDAY, Jan. 27, 2014 (HealthDay News) -- Hormone replacement therapy use (HRT) is associated with a reduction in revision rates for total knee arthroplasty (TKA) and total hip arthroplasty (THA), according to a study published online Jan. 22 in the Annals of the Rheumatic Diseases.
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Stimulant, Antipsychotic Combo Improves Aggressive Behavior
FRIDAY, Jan. 24, 2014 (HealthDay News) -- For children with attention deficit/hyperactivity disorder (ADHD) and aggressive disorders, the addition of risperidone to a combination of parent training and psychostimulant is associated with moderate improvement in aggressive and disruptive behaviors, according to a study published in the January issue of the Journal of the American Academy of Child & Adolescent Psychiatry.
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Sickle Cell Trait Affects Dosing of Anemia Medications in Dialysis
FRIDAY, Jan. 24, 2014 (HealthDay News) -- African-American patients undergoing hemodialysis who carry hemoglobinopathy traits such as sickle cell trait require higher doses of erythropoiesis-stimulating agents (ESAs) than patients without these traits, according to a study published online Jan. 23 in the Journal of the American Society of Nephrology.
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Community-Wide Preventive Isoniazid Tx Ineffective for TB
THURSDAY, Jan. 23, 2014 (HealthDay News) -- Community-wide isoniazid preventive therapy does not improve tuberculosis (TB) control in miners, according to a study published in the Jan. 23 issue of the New England Journal of Medicine.
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Phase 3 Studies Fail to Show Benefit of Drugs in Alzheimer's
WEDNESDAY, Jan. 22, 2014 (HealthDay News) -- For patients with mild-to-moderate Alzheimer's disease, neither bapineuzumab nor solanezumab improves cognitive outcomes, according to two studies published in the Jan. 23 issue of the New England Journal of Medicine.
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Legitimacy of Publishing Pharma-Funded Research Queried
WEDNESDAY, Jan. 22, 2014 (HealthDay News) -- The question of whether to stop publishing research funded by the drug industry is addressed in a head-to-head piece published online Jan. 15 in BMJ.
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Chinese Herb Capsule May Help Reduce Progression to Diabetes
WEDNESDAY, Jan. 22, 2014 (HealthDay News) -- A Tianqi capsule containing 10 Chinese herbal medicines significantly reduces the incidence of type 2 diabetes mellitus (T2DM) in individuals with impaired glucose tolerance (IGT), according to a study published online Jan. 16 in the Journal of Clinical Endocrinology amp; Metabolism.
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Pediatric AOM Costs Health Care System ~$2.88 Billion Annually
TUESDAY, Jan. 21, 2014 (HealthDay News) -- Pediatric acute otitis media (AOM) is associated with increased health care utilization and costs, adding approximately $2.88 billion in health care expense annually, according to a study published in the January issue of The Laryngoscope.
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ACA Impact on Primary Practice May Depend on Location
TUESDAY, Jan. 21, 2014 (HealthDay News) -- The impact of Medicaid expansion under the Affordable Care Act (ACA) on physicians' primary care practices will vary geographically, according to an article published Dec. 25 in Medical Economics.
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More Federal Funding of Health Centers Mitigates Access Issues
TUESDAY, Jan. 21, 2014 (HealthDay News) -- Since 2000, increased federal funding for community health centers has helped low-income adults get access to primary care and dental care, according to a study published online Dec. 18 in Health Services Research.
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Researchers Examine FDA Decision Making Processes
TUESDAY, Jan. 21, 2014 (HealthDay News) -- The rationale behind the decision making processes of the U.S. Food and Drug Administration is discussed in three articles published in the Jan. 22/29 issue of the Journal of the American Medical Association.
Abstract - Downing
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Multiple Medications Increase Odds of Hospital Admission
TUESDAY, Jan. 21, 2014 (HealthDay News) -- The likelihood of unplanned admission is increased with polypharmacy, but the association is modified by the number of long-term conditions, according to a study published online Jan. 16 in the British Journal of Clinical Pharmacology.
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Medication Synchronization Program Ups Adherence
TUESDAY, Jan. 21, 2014 (HealthDay News) -- A community pharmacy-based medication synchronization program can improve medication adherence, according to a study conducted by the National Community Pharmacists Association (NCPA).
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Statin Use Linked to Reduced Delirium in ICU Patients
MONDAY, Jan. 20, 2014 (HealthDay News) -- For critically ill patients in the intensive care unit (ICU), statin use is associated with a reduced risk of delirium, according to a study published online Jan. 17 in the American Journal of Respiratory and Critical Care Medicine.
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AMA Launches Online Resource to Guide HTN Management
MONDAY, Jan. 20, 2014 (HealthDay News) -- An online resource has been developed for improving the detection and management of high blood pressure. The resource is part of the American Medical Association's Improving Health Outcomes Initiative which aims to improve outcomes around heart disease, starting with the 30 million people who have uncontrolled hypertension.
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State Insurance Marketplaces Boost Outreach Efforts
THURSDAY, Jan. 16, 2014 (HealthDay News) -- Health insurance exchanges in five states with strong enrollment growth are ramping up efforts to reach even more uninsured Americans before the end of the Affordable Care Act's open enrollment period on March 31. The March 31 deadline is for people who want health coverage for 2014.
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Reliable Emotion Words ID'd to Assess Patient Experience
THURSDAY, Jan. 16, 2014 (HealthDay News) -- A reliable set of emotion words have been identified that can serve as a tool for experience-based design questionnaires in health care, according to a study published in the December issue of Healthcare.
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FDA Warns of Fires From Some Cryogenic Wart Removers
THURSDAY, Jan. 16, 2014 (HealthDay News) -- Flammable over-the-counter wart removers have started fires, injuring at least 10 people in recent years, the U.S. Food and Drug Administration says.
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NCPA: Access to Controlled Substances Often Delayed
THURSDAY, Jan. 16, 2014 (HealthDay News) -- Most pharmacists report experiencing multiple delays or issues with their controlled substance orders, according to the results of the National Community Pharmacists Association (NCPA) Controlled Substances Access Survey.
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FDA Warns Against Rx With High Levels of Acetaminophen
WEDNESDAY, Jan. 15, 2014 (HealthDay News) -- The U.S. Food and Drug Administration is recommending that physicians stop prescribing and dispensing prescription combination drug products containing more than 325 mg of acetaminophen per tablet, according to a safety alert issued by the agency.
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Interferon-Free Combo of ABT-450, Ritonavir Helpful for Hep C
WEDNESDAY, Jan. 15, 2014 (HealthDay News) -- Treatment with an interferon-free combination of the protease inhibitor ABT-450 with ritonavir, or daclatasvir plus sofosbuvir, is associated with high rates of sustained virologic response in hepatitis C virus (HCV) infection, according to two studies published in the Jan. 16 issue of the New England Journal of Medicine.
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Pritelivir Safe, Effective for Genital HSV-2 Infection
WEDNESDAY, Jan. 15, 2014 (HealthDay News) -- Pritelivir is safe and effective for treatment of genital herpes simplex virus (HSV)-2 infection, according to a study published in the Jan. 16 issue of the New England Journal of Medicine.
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Beliefs About Safety May Spark E-Cigarette Use in Young Adults
WEDNESDAY, Jan. 15, 2014 (HealthDay News) -- Young adults who believe that electronic cigarettes (e-cigarettes) are less harmful and can help people quit smoking are more likely to try them, according to research published online Jan. 7 in the American Journal of Preventive Medicine.
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Merck Recalls Cholesterol Drug Liptruzet
TUESDAY, Jan. 14, 2014 (HealthDay News) -- Packaging defects have prompted a recall of the combination cholesterol drug Liptruzet, produced by Merck & Co., temporarily affecting the entire U.S. stock.
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Green Tea May Interfere With Antihypertensive
TUESDAY, Jan. 14, 2014 (HealthDay News) -- Drinking green tea may lessen the effects of the antihypertensive medication nadolol (Corgard), according to research published online Jan. 13 in Clinical Pharmacology & Therapeutics.
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Peptide Boosts Drug Efficacy in Pulmonary Arterial Hypertension
TUESDAY, Jan. 14, 2014 (HealthDay News) -- A peptide that specifically homes to hypertensive pulmonary arteries can be used to boost the efficacy of vasodilators in a rat model of pulmonary arterial hypertension (PAH), according to a study published online Jan. 8 in The American Journal of Pathology.
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Risk of Intussusception Still Up After New Rotavirus Vaccination
TUESDAY, Jan. 14, 2014 (HealthDay News) -- The risk of intussusception is still increased after administration of the new rotavirus vaccines, but the risk is lower than that seen with previous vaccines, according to two studies published online Jan. 14 in the New England Journal of Medicine. The studies were published ahead-of-print to coincide with the sixth annual Sentinel Initiative Public Workshop at the Brookings Institution, held on Jan. 14 in Washington, D.C.
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Wednesday Is Deadline for Feb. 1 Coverage Under ACA
TUESDAY, Jan. 14, 2014 (HealthDay News) -- There's still time to enroll in a health insurance plan through one of the Affordable Care Act's new online marketplaces. Those who sign up by Wednesday will have coverage starting next month.
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More Than Two Million People Have Signed Up for ACA Coverage
TUESDAY, Jan. 14, 2014 (HealthDay News) -- Nearly 2.2 million Americans had selected health plans through the federal and state marketplaces as of late December, and nearly one in four was a young adult, the Obama administration disclosed Monday.
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Testosterone Often Initiated in Men With Normal Levels
MONDAY, Jan. 13, 2014 (HealthDay News) -- Testosterone testing and supplementation have increased substantially over the last decade, with many men in the United States initiating treatment even though they have normal levels, according to a study published online Jan. 1 in the Journal of Clinical Endocrinology & Metabolism.
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Suicide Risk Equal for Children Taking Single Antidepressant
MONDAY, Jan. 13, 2014 (HealthDay News) -- The risk of suicide attempts among children and adolescents treated with individual selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) does not differ compared with that among current users of fluoxetine, according to a study published online Jan. 6 in Pediatrics.
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CMS: New Rule Proposed for Contract Year 2015
MONDAY, Jan. 13, 2014 (HealthDay News) -- A proposed rule has been issued that will strengthen protections, improve health care quality, and reduce costs for Medicare beneficiaries with private Medicare Advantage and Part D prescription plans, according to a report from the Centers for Medicare & Medicaid Services (CMS).
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FDA Approves Mekinist Plus Tafinlar for Late-Stage Melanoma
FRIDAY, Jan. 10, 2014 (HealthDay News) -- The U.S. Food and Drug Administration has approved Mekinist for use with another drug, Tafinlar, to treat advanced melanoma that is metastatic or unresectable.
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Parkinson's Gene Therapy Improves Motor Function
FRIDAY, Jan. 10, 2014 (HealthDay News) -- A triple gene therapy for Parkinson's disease is safe and improves motor function, according to a study published online Jan. 10 in The Lancet.
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FDA Approves Gel for Sealing Cataract Surgery Incision
FRIDAY, Jan. 10, 2014 (HealthDay News) -- A sealant gel to prevent fluid leakage after cataract surgery has been approved by the U.S. Food and Drug Administration.
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ACP Introduces Free 'High Value Care' Case Studies
FRIDAY, Jan. 10, 2014 (HealthDay News) -- In an effort to improve health care and eliminate wasteful practices, the American College of Physicians (ACP) has developed a series of High Value Care cases studies, available online for free.
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CMS: Low Growth for National Health Expenditures in 2012
FRIDAY, Jan. 10, 2014 (HealthDay News) -- Overall national health expenditures were marked by a fourth consecutive year of low growth, according to a report from the Centers for Medicare & Medicaid Services.
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Female Conveners Up Number of Women at Scientific Symposia
FRIDAY, Jan. 10, 2014 (HealthDay News) -- Having at least one woman on teams that convene scientific symposia increases the proportion of invited female speakers by 72 percent, compared with teams containing all men, according to a study published online Jan. 7 in mBio.
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EHR Use Linked to Doc-Reported Enhanced Patient Care
FRIDAY, Jan. 10, 2014 (HealthDay News) -- Use of electronic health records is associated with enhanced patient care overall, according to a study published online Dec. 21 in Health Services Research.
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Lithium May Promote Recovery in Acute Kidney Injury
FRIDAY, Jan. 10, 2014 (HealthDay News) -- The mood stabilizer lithium promotes the recovery of renal function and repair in mouse models of acute kidney injury (AKI), according to a study published online Jan. 9 in the Journal of the American Society of Nephrology.
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Extended Varenicline Use Ups Smoking Abstinence Rates
THURSDAY, Jan. 9, 2014 (HealthDay News) -- Extended use of the smoking cessation medication varenicline improves abstinence rates among the mentally ill, according to a study published in the Jan. 8 issue of the Journal of the American Medical Association, a theme issue on tobacco control.
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Most Ped OTC Liquid Med Labels Adhere to FDA Dosing Guidelines
THURSDAY, Jan. 9, 2014 (HealthDay News) -- Most over-the-counter (OTC) pediatric liquid medication directions adhere to the U.S. Food and Drug Administration dosing recommendations; and maternal OTC analgesic use is associated with child use of OTC analgesics, according to two studies published online Jan. 6 in Pediatrics.
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Impact of In Utero Epilepsy Med Exposure Studied in Children
THURSDAY, Jan. 9, 2014 (HealthDay News) -- Compared to children exposed in utero to sodium valproate, children exposed in utero to levetiracetam for treatment of maternal epilepsy have superior language and motor development at age 36 to 54 months, according to a study published online Jan. 8 in Neurology.
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Conventional Versus Intensive T1DM Tx Not Tied to Menopause
THURSDAY, Jan. 9, 2014 (HealthDay News) -- For women with type 1 diabetes, intensive versus conventional treatment is not associated with menopause risk, although greater insulin dose is associated with lower natural menopause risk, according to research published in Diabetes Care.
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Drug Labeling Linked to Drug, Placebo Efficacy in Migraine
THURSDAY, Jan. 9, 2014 (HealthDay News) -- For patients with episodic migraine, the information provided about drug/placebo impacts drug effects, according to a study published in the Jan. 8 issue of Science Translational Medicine.
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FDA Approves Farxiga for Type 2 Diabetes
WEDNESDAY, Jan. 8, 2014 (HealthDay News) -- Farxiga (dapaglifozin) has been approved by the U.S. Food and Drug Administration to treat adults with type 2 diabetes, the agency said Wednesday in a news release.
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Liquid Tamiflu for Children in Short Supply
WEDNESDAY, Jan. 8, 2014 (HealthDay News) -- Manufacturing problems have created a shortage of the liquid form of Tamiflu, which is designed for young children who can't swallow capsules, U.S. health officials announced Wednesday.
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No Long-Term Benefit Seen for Smoking Cessation Combo Rx
WEDNESDAY, Jan. 8, 2014 (HealthDay News) -- Combination treatment with varenicline plus bupropion sustained-release is initially more effective than varenicline alone in promoting smoking abstinence, but the results are not long-lasting, according to a study published in the Jan. 8 issue of the Journal of the American Medical Association, a theme issue on tobacco control.
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Anti-CD20 Antibody + Chemo Benefits CLL With Comorbidity
WEDNESDAY, Jan. 8, 2014 (HealthDay News) -- For patients with previously untreated chronic lymphocytic leukemia (CLL) and coexisting conditions, combining an anti-CD20 antibody (rituximab or obinutuzumab) with chemotherapy is associated with improved outcomes, according to a study published online Jan. 8 in the New England Journal of Medicine.
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Smoking Rates Still Low for Most Health Care Professionals
WEDNESDAY, Jan. 8, 2014 (HealthDay News) -- Compared with 2006 to 2007, smoking rates among health care professionals for 2010 to 2011 continue to be lowest in physicians and highest in licensed practical nurses (LPNs), according to a research letter published in the Jan. 8 issue of the Journal of the American Medical Association, a theme issue on tobacco control.
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Herpes Zoster Is Risk Factor for Stroke in Young Adults
MONDAY, Jan. 6, 2014 (HealthDay News) -- Herpes zoster (HZ) is an independent risk factor for vascular disease, including stroke, transient ischemic attack (TIA), and myocardial infarction (MI), particularly in those affected before the age of 40 years, according to a study published online Jan. 2 in Neurology.
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Obama Administration Stands by Contraception Rule
MONDAY, Jan. 6, 2014 (HealthDay News) -- The Obama administration on Friday contested U.S. Supreme Court Justice Sonia Sotomayor's decision temporarily exempting an order of Catholic nuns from the Affordable Care Act's contraception mandate.
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Romosozumab Increases Bone Mineral Density Post-Menopause
MONDAY, Jan. 6, 2014 (HealthDay News) -- Romosozumab seems safe and effective for increasing bone mineral density in postmenopausal women with low bone mineral density, according to a study published online Jan. 1 in the New England Journal of Medicine.
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Guidelines for Management of Menopausal Symptoms Issued
MONDAY, Jan. 6, 2014 (HealthDay News) -- Evidence-based treatment guidelines for menopause management include personalizing treatment for optimal symptom relief, according to a Practice Bulletin published in the January issue of Obstetrics & Gynecology.
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CDC Addresses Burden, Threat of Antibiotic Resistance
MONDAY, Jan. 6, 2014 (HealthDay News) -- The burden and threats posed by antibiotic resistance infections are discussed in a report published by the U.S. Centers for Disease Control and Prevention.
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AMA Details Top Five Federal Issues for 2014
MONDAY, Jan. 6, 2014 (HealthDay News) -- Implementation of the Affordable Care Act, the repeal of Medicare's failed sustained growth formula, and the proposed roll-out of the International Classification of Diseases, Version 10, top the list of federal issues expected to impact physicians and patients in 2014, according to a viewpoint piece published online Dec. 30 by the American Medical Association (AMA).
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Over 100 New Accountable Care Organizations Formed
FRIDAY, Jan. 3, 2014 (HealthDay News) -- One hundred twenty-three new Accountable Care Organizations (ACOs) have been formed by doctors, hospitals, and other health care providers, which will provide access to high-quality coordinated care for about 1.5 million Medicare beneficiaries, according to a report from the U.S. Department of Health and Human Services.
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NSAID Diflunisal Slows Neurodegenerative Progression
FRIDAY, Jan. 3, 2014 (HealthDay News) -- The nonsteroidal anti-inflammatory agent diflunisal slows the rate of neurodegenerative progression associated with familial amyloid polyneruopathy, according to a study published in the Dec. 25 issue of the Journal of the American Medical Association.
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Warfarin Initiation Negatively Linked to Stroke in A-Fib Patients
FRIDAY, Jan. 3, 2014 (HealthDay News) -- Patients with atrial fibrillation are at higher risk of having a stroke in the first month after initiating treatment with the anti-clotting drug warfarin, according to a study published online Dec. 18 in European Heart Journal.
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Doctors Discuss Use of MenB Vaccine at Princeton University
FRIDAY, Jan. 3, 2014 (HealthDay News) -- The planned use of an experimental Neisseria meningitides serogroup B (MenB) meningitis vaccine at the University of Princeton has raised several contentious issues relating to vaccination, according to an ideas and opinions piece published online Dec. 24 in the Annals of Internal Medicine.
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Usage, Cost of Antibiotics for Children Higher in U.S. Versus U.K.
THURSDAY, Jan. 2, 2014 (HealthDay News) -- For young children, the usage and cost of antibiotics is considerably higher in the United States than in the United Kingdom, according to a study published online Dec. 18 in Pharmacotherapy.
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Increasing BMI Tied to Steady Increase in Health Care Costs
THURSDAY, Jan. 2, 2014 (HealthDay News) -- Health care costs increase steadily with increasing body mass index (BMI), with the increase starting at a BMI of 19, according to a study published online Dec. 9 in Obesity.
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CDC: Updated Guidance for HBV Vaccination for Health Workers
THURSDAY, Jan. 2, 2014 (HealthDay News) -- Health care personnel should be vaccinated against hepatitis B virus (HBV) if they anticipate exposure to blood or body fluids, and receive serologic testing to assess for antibody against the virus, according to updated guidelines published in the Dec. 20 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
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Alpha Tocopherol Seems Beneficial in Alzheimer's
THURSDAY, Jan. 2, 2014 (HealthDay News) -- For patients with mild-to-moderate Alzheimer's disease, alpha tocopherol is associated with slower functional decline versus placebo, according to a study published in the Jan. 1 issue of the Journal of the American Medical Association.
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Pharmacies Often Misinform Young Females About Plan B
THURSDAY, Jan. 2, 2014 (HealthDay News) -- Female adolescents requesting emergency contraception (EC) at pharmacies are often given incorrect information, partly due to confusion about changing regulations, according to a study published in the January issue of the Journal of Adolescent Health.
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