Deep Learning Model Helps Predict Neonatal Outcomes

Area under receiver operating characteristic curve at delivery exceeded 0.9 for 10 of 24 neonatal outcomes considered
newborn baby girl getting light therapy inside incubator at hospital
newborn baby girl getting light therapy inside incubator at hospitalAdobe Stock
Medically Reviewed By:
Mark Arredondo, M.D.

FRIDAY, Feb. 17, 2023 (HealthDay News) -- A multitask deep learning model based on data from electronic health records (EHRs) can predict neonatal outcomes, according to a study published in the Feb. 15 issue of Science Translational Medicine.

Davide De Francesco, Ph.D., from the Stanford University School of Medicine in California, and colleagues proposed a longitudinal risk assessment for adverse neonatal outcomes in newborns based on a deep learning model that uses EHRs to predict a range of outcomes starting shortly before conception and ending months after birth. A cohort of 22,104 mother-newborn dyads delivered between 2014 and 2018 was developed. A multi-input multitask deep learning model was trained using maternal and newborn EHRs to predict 24 neonatal outcomes. The model was validated using an additional cohort of 10,205 mother-newborn dyads delivered from 2019 to September 2020.

The researchers found that for 10 of the 24 neonatal outcomes, areas under the receiver operating characteristic curve at delivery exceeded 0.9; for seven additional outcomes, they were between 0.8 and 0.9. Multiple known associations between various maternal and neonatal features and specific neonatal outcomes were identified in a comprehensive association analysis.

"This is a new way of thinking about preterm birth, placing the focus on individual health factors of the newborns rather than looking only at how early they are born," a coauthor said in a statement.

Several authors disclosed financial ties to the biopharmaceutical industry.

Abstract/Full Text

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