Predictors Identified for Incident DSM-IV Disorders

Risk of substance use, mood and anxiety disorders varies by gender, age and ethnicity

THURSDAY, April 24 (HealthDay News) -- The one-year incidence rates for substance use and mood and anxiety disorders vary by gender, age and ethnicity, according to a study published online April 22 in Molecular Psychiatry.

Bridget F. Grant, Ph.D., of the National Institute on Alcohol Abuse and Alcoholism at the National Institutes of Health in Bethesda, Md., and colleagues assessed data on the three-year prospective follow-up of 34,653 subjects who were enrolled in the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions.

The researchers found that one-year incidence rates of DSM-IV substance, mood and anxiety disorders were highest for alcohol abuse (1.02), alcohol dependence (1.7), major depressive disorder (1.51) and generalized anxiety disorder (1.12). Men had significantly higher rates for substance use disorders, women had higher rates for mood and anxiety disorders (with the exceptions of bipolar disorders and social phobia), and younger people had an increased risk of all disorders. Blacks had a decreased risk of incident alcohol abuse, and Hispanics had a decreased risk of generalized anxiety disorder.

"Information on risk factors for first-onset specific psychiatric disorders can inform the development of evidence-based prevention and education programs targeting sociodemographic and psychopathologic precursors," the authors write. "Knowledge of psychopathologic risk factors can also guide etiologic investigations of common and unique genetic and environmental influences underlying comorbidity, and provide more etiologically derived phenotypes for genetic research."

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