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March 2014 Briefing - Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for March 2014. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Bipolar Disorder-Derived Neurons Have Distinct Transcripts

FRIDAY, March 28, 2014 (HealthDay News) -- Neurons differentiated from bipolar disorder patient-derived induced pluripotent stem cells (iPSCs) have a significantly different transcription profile than those from controls, according to a study published online March 25 in Translational Psychology.

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Phone App Cuts Risky Drinking in Recovering Alcoholics

FRIDAY, March 28, 2014 (HealthDay News) -- A phone app can provide positive continuing care for patients with alcohol use disorders following discharge from a residential treatment facility, according to a study published online March 26 in JAMA Psychiatry.

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Depression May Worsen Kidney Disease in Diabetes Patients

FRIDAY, March 28, 2014 (HealthDay News) -- Patients with diabetes who have comorbid major depression may be at greater risk of end-stage renal disease (ESRD), according to research published online March 27 in the Clinical Journal of the American Society of Nephrology.

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Urinary Incontinence Ups Risk of Depression in Older Women

FRIDAY, March 28, 2014 (HealthDay News) -- Older women with urinary incontinence may be at increased risk for depression and work disability, according to research published in the April issue of Obstetrics & Gynecology.

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CDC: U.S. Autism Estimates Rise by 30 Percent for Children

THURSDAY, March 27, 2014 (HealthDay News) -- One in 68 American children are now diagnosed with autism or a related disorder, according to a report published in the March 28 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report. That's a 30 percent increase from just two years ago when the estimate was one in 88 children.

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NIH Launches Online Resource for End-of-Life Issues

THURSDAY, March 27, 2014 (HealthDay News) -- People grappling with terminal illness now have a new online source of advice and help, sponsored by the U.S. National Institute on Aging, part of the National Institutes of Health.

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Aggressive Cognitions Mediate Impact of Violent Video Games

THURSDAY, March 27, 2014 (HealthDay News) -- The effect of playing violent video games on later aggressive behavior seems to be mediated primarily by aggressive cognitions, according to a study published online March 24 in JAMA Pediatrics.

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NCHS Estimates Health Insurance Coverage for 2013

THURSDAY, March 27, 2014 (HealthDay News) -- In the first nine months of 2013, 6.7 percent of children and 20.5 percent of adults were uninsured, according to a study published online March 27 by the National Center for Health Statistics (NCHS).

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Galanin System Genes Linked to Risk of Depression in Stress

THURSDAY, March 27, 2014 (HealthDay News) -- Variants of the stress-inducible neuropeptide and cotransmitter in serotonin and norepinephrine neurons, galanin, and its receptors confers increased risk of depression and anxiety among highly stressed individuals, according to a study published online March 24 in the Proceedings of the National Academy of Sciences.

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Brain Stimulation Improves QoL in Fibromyalgia Patients

THURSDAY, March 27, 2014 (HealthDay News) -- Repetitive transcranial magnetic stimulation (rTMS) may improve quality of life (QoL) in patients with fibromyalgia, according to research published online March 26 in Neurology.

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Focal Disruption of Cortical Laminar Architecture in Autism

WEDNESDAY, March 26, 2014 (HealthDay News) -- Most young children with autism have focal disruption of cortical laminar architecture, according to a study published in the March 27 issue of the New England Journal of Medicine.

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White House Extends Affordable Care Act Enrollment Deadline

WEDNESDAY, March 26, 2014 (HealthDay News) -- Americans who've started applying for health insurance under the Affordable Care Act but can't complete the process by the March 31 enrollment deadline will be given an extension.

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AMA Introduces Medical Education Initiative

WEDNESDAY, March 26, 2014 (HealthDay News) -- The American Medical Association's (AMA) Accelerating Change in Education initiative is being introduced in 11 medical schools in an effort to shift the focus of education toward real-world practice and competency assessment, according to an AMA report.

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Americans Seem Unprepared for Health Insurance Exchanges

WEDNESDAY, March 26, 2014 (HealthDay News) -- Individuals in the United States seem not to be sufficiently informed about the health insurance exchanges established by the Affordable Care Act (ACA), according to a study published online March 24 in the Proceedings of the National Academy of Sciences.

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Childhood Abuse May Up Risk of Adult Obesity

TUESDAY, March 25, 2014 (HealthDay News) -- Early-life adversity may contribute to metabolic abnormalities that lead to obesity later in life, according to research published online March 20 in the Journal of Clinical Endocrinology & Metabolism.

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Preconception Stress Ups the Risk of Infertility in Women

TUESDAY, March 25, 2014 (HealthDay News) -- Higher levels of stress as measured by salivary amylase levels are associated with reduced fecundity and increased risk of infertility, according to research published in online March 23 in Human Reproduction.

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Slight Delay Improves Decision-Making Accuracy

TUESDAY, March 25, 2014 (HealthDay News) -- Decision-making accuracy can be improved by slightly delaying decision onset, according to a study published online March 5 in PLOS ONE.

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Valproic Acid Use May Reduce Incidence of Head, Neck Cancer

MONDAY, March 24, 2014 (HealthDay News) -- Long-term use of valproic acid (VPA) is associated with a reduced risk of smoking-related cancers of the head and neck, according to a study published online March 24 in Cancer.

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USPSTF: Evidence Lacking for Cognitive Impairment Screening

MONDAY, March 24, 2014 (HealthDay News) -- The United States Preventive Services Task Force (USPSTF) has found that evidence is currently insufficient to weigh the benefits and harms of universal screening for cognitive impairment in older adults. These findings are presented in a final recommendation statement published online March 25 in the Annals of Internal Medicine.

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Patient Request Impacts Doc Prescribing Behavior

MONDAY, March 24, 2014 (HealthDay News) -- Patients requesting specific medications are more likely to be prescribed those medications, according to research published in the April issue of Medical Care.

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Husbands' Health, Attitude Play Larger Role in Marital Conflict

FRIDAY, March 21, 2014 (HealthDay News) -- In older married couples, the husband's health and attitude seem to affect perceptions of marital conflict, according to a study published in the February issue of the Journal of Marriage and Family.

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Practices Can Take Steps to Improve Care Transitions

FRIDAY, March 21, 2014 (HealthDay News) -- Implementation of a rigorous process can improve transitions of care, according to an article published March 10 in Medical Economics.

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Older Drivers More Susceptible to the Effects of Alcohol

FRIDAY, March 21, 2014 (HealthDay News) -- Older adults' driving performance may be more susceptible to the effects of alcohol, according to a study published in the February issue of Psychopharmacology.

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Stress-Linked Protein May Play Major Role in Alzheimer's

FRIDAY, March 21, 2014 (HealthDay News) -- Dysfunction in the brain's stress response system may be an important factor in the memory and thinking problems experienced by people with Alzheimer's disease and other dementias, according to a report published online March 19 in Nature.

Health Highlights: March 20, 2014
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Alzheimer's Strikes Women Harder Than Men: Report

THURSDAY, March 20, 2014 (HealthDay News) -- A 65-year-old American woman has a one in six chance of developing Alzheimer's disease later in life, while a man the same age has about a one in 11 chance, according to a report published in the March issue of Alzheimer's & Dementia, the journal of the Alzheimer's Association.

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Pre-Existing Psych Diagnoses Higher in Critically Ill Patients

WEDNESDAY, March 19, 2014 (HealthDay News) -- Existing psychiatric diagnoses are more common in critically ill patients compared to other hospitalized patients and the general population, according to a study published in the March 19 issue of the Journal of the American Medical Association.

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Way Cleared for Study on Marijuana for Vets With PTSD

TUESDAY, March 18, 2014 (HealthDay News) -- A long-delayed study to examine the use of marijuana in treating U.S. veterans with posttraumatic stress disorder will finally begin after the federal government removed a major roadblock.

Other Health Highlights: March 18, 2014

Elevated Levels of Brain Injury Biomarkers in Concussion

TUESDAY, March 18, 2014 (HealthDay News) -- Ice hockey players with sports-related concussion have elevations in the axonal injury biomarker total tau and the astroglial injury biomarker S-100 calcium-binding protein B, according to a study published online March 13 in JAMA Neurology.

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Riding With Impaired Driver Ups Teen Risk of Driving Impaired

TUESDAY, March 18, 2014 (HealthDay News) -- Teenagers exposed to alcohol/drug impaired driving (riding while impaired [RWI]) have an increased likelihood of driving while alcohol/drug impaired (DWI) themselves, according to a study published online March 17 in Pediatrics.

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Personality Measures in Young Patients Predict Later Health

TUESDAY, March 18, 2014 (HealthDay News) -- Personality measurements can be useful tools in predicting which young adult patients will have poor health in middle age, according to a study published in the March issue of the Journal of Personality and Social Psychology.

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For Girls, Obesity at Age 11 Impairs Academic Attainment

TUESDAY, March 18, 2014 (HealthDay News) -- For girls, obesity at age 11 years has a negative effect on academic attainment, according to a study published online March 11 in the International Journal of Obesity.

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Rx Expenditures Expected to Rise in 2014

MONDAY, March 17, 2014 (HealthDay News) -- Drug costs are projected to rise 3 to 5 percent across all care settings in 2014, according to a study published in the March 15 issue of the American Journal of Health-System Pharmacy.

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Oxytocin Seems Beneficial for Patients With Anorexia

MONDAY, March 17, 2014 (HealthDay News) -- For females with anorexia nervosa, oxytocin attenuates attentional vigilance to eating and fat shape stimuli and affects attentional processes to social emotional stimuli, according to two studies published online in Psychoneuroendocrinology and PLOS ONE.

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Insurers Must Offer Same-Sex Couples Spousal Benefits

MONDAY, March 17, 2014 (HealthDay News) -- Health plans that offer benefits for heterosexual couples must do the same for same-sex married couples, the Obama administration says.

Other Health Highlights: March 17, 2014

Pediatric Hospitalizations for Depression Are Costly, Common

MONDAY, March 17, 2014 (HealthDay News) -- Among inpatient diagnoses for child mental health, depression is one of the most frequent and costly reasons for pediatric hospitalizations, according to research published online March 17 in Pediatrics.

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Study Shows Stimulant Use Impacts ADHD, BMI Link

MONDAY, March 17, 2014 (HealthDay News) -- Children with attention-deficit/hyperactivity disorder (ADHD) not treated with stimulants have higher body mass index (BMI), while those treated with stimulants have lower BMI earlier in childhood and more rapid rebound to higher BMI in late adolescence, according to a study published online March 17 in Pediatrics.

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Animal Protein May Slow Functional Decline in Older Men

MONDAY, March 17, 2014 (HealthDay News) -- Among older men, higher intake of protein, particularly animal protein, is associated with lower risk of decline in higher-level functional capacity, according to research published in the March issue of the Journal of the American Geriatrics Society.

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Weaker Brain Network Connectivity in Abstinent Smokers

MONDAY, March 17, 2014 (HealthDay News) -- Abstinent smokers show weaker brain inter-network connectivity between the salience, executive control, and default modes, according to a study published online March 12 in JAMA Psychiatry.

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Improving EHR Interoperability Is a National Priority: HHS

FRIDAY, March 14, 2014 (HealthDay News) -- Interoperability of electronic health record (EHR) systems is a national priority of the Office of the National Coordinator for Health Information Technology, according to an article published March 4 in Medical Economics.

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CDC: Most Alcohol-Linked Deaths Occur Among Working-Age Adults

FRIDAY, March 14, 2014 (HealthDay News) -- Americans' excessive alcohol use contributes to thousands of deaths each year, and the majority who die are working-age adults, according to a report published in the March 14 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Review: Peer Victimization Ups Child Suicide Ideation, Attempts

THURSDAY, March 13, 2014 (HealthDay News) -- For children and adolescents, peer victimization is associated with increased odds of suicidal ideation and suicide attempts, with cyberbullying more strongly linked to suicidal ideation, according to a meta-analysis published online March 10 in JAMA Pediatrics.

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IOM Recommends Definitions for 'Gulf War' Multisymptom Illness

THURSDAY, March 13, 2014 (HealthDay News) -- Two definitions for chronic multisymptom illness should be used to identify cases of Gulf War illness among Gulf War veterans, according to a report published by the Institute of Medicine.

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AMA: CMS Wants Physician Input on Practice Transformation

WEDNESDAY, March 12, 2014 (HealthDay News) -- Physicians are being given the opportunity to describe what resources they need in order to transition to value-based models of care, according to a report published by the American Medical Association (AMA).

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TV Viewing Time Linked to Sleep Duration in Children

WEDNESDAY, March 12, 2014 (HealthDay News) -- For children, television viewing time is inversely associated with sleep duration, according to a study published online March 10 in JAMA Pediatrics.

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About One-Quarter of Patients With MCI Progress to Dementia

WEDNESDAY, March 12, 2014 (HealthDay News) -- About 22 percent of patients with mild cognitive impairment (MCI) progress to dementia within three years, and depression symptoms modify the prognosis, according to a study published in the March/April issue of the Annals of Family Medicine.

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White House: More Than Four Million Have Signed Up for ACA

TUESDAY, March 11, 2014 (HealthDay News) -- More than four million Americans have signed up for health coverage through state and federal insurance marketplaces established by the Affordable Care Act, the Obama administration announced Tuesday.

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Medicare Drug Plan Changes Withdrawn by White House

TUESDAY, March 11, 2014 (HealthDay News) -- Proposed changes to the Medicare prescription drug program have been withdrawn by the Obama administration after strong opposition from patient groups.

Other Health Highlights: March 11, 2014

Discrepancies ID'd in Studies on ClinicalTrials.gov, Journals

TUESDAY, March 11, 2014 (HealthDay News) -- Nearly all clinical trials reported on ClinicalTrials.gov and published in high-impact journals report at least one discrepancy in cohort, intervention, or results, according to a research letter published in the March 12 issue of the Journal of the American Medical Association.

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Family Routines Aid Emotional Health of Preschoolers

TUESDAY, March 11, 2014 (HealthDay News) -- Promoting family routines may contribute to greater social-emotional health (SEH) in preschool-aged children, according to a study published in the February/March issue of the Journal of Developmental & Behavioral Pediatrics.

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USPSTF: Evidence Lacking for Drug Use Interventions

TUESDAY, March 11, 2014 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) has found that there is currently insufficient evidence to recommend primary care interventions to prevent or reduce illicit drug use or nonmedical prescription drug use among youth. The findings are presented in a final recommendation statement published online March 11 in the Annals of Internal Medicine.

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Marijuana Use Up, Cocaine Use Down, U.S. Report Finds

MONDAY, March 10, 2014 (HealthDay News) -- Americans' use of cocaine fell by half from 2006 to 2010, but marijuana use increased by more than 30 percent during that time, according to a new report. The spike in pot use may be due to an increase in the number of people who said they use the drug on a daily or near-daily basis, said the researchers, whose study covered drug trends from 2000 to 2010. Heroin use remained fairly stable during the decade, while methamphetamine use rose sharply during the first half of the decade and then fell.

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Blood Test May Have Power to Predict Alzheimer's Disease

MONDAY, March 10, 2014 (HealthDay News) -- A blood test has been developed that can predict with 90 percent certainty whether a senior will suffer from dementia such as Alzheimer's disease within the next few years, according to a study published online March 9 in Nature Medicine. The test relies on levels of 10 lipids in the bloodstream to estimate the chances of either mild cognitive impairment or the beginnings of Alzheimer's disease.

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Parental Death Increases Odds of Lower Grades, School Failure

MONDAY, March 10, 2014 (HealthDay News) -- Children who experience parental death are more likely to have lower grades and school failure, according to a study published online March 10 in Pediatrics.

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Hearing Impairment in Adults Linked to Depression

MONDAY, March 10, 2014 (HealthDay News) -- Hearing impairment (HI) is associated with depression, especially for older women, according to a study published online March 6 in JAMA Otolaryngology-Head & Neck Surgery.

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Keeping Salaries Secret Harms Worker Performance

MONDAY, March 10, 2014 (HealthDay News) -- Keeping salaries secret hurts worker performance and increases turnover of top talent, according to a study published online Jan. 13 in the Academy of Management Journal.

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Concern Over Facebook Photos Tied to Eating Disorders

MONDAY, March 10, 2014 (HealthDay News) -- Young women who spend more time on Facebook self-report a higher incidence of appearance-focused behaviors and greater eating pathology, according to research published online Jan. 24 in the International Journal of Eating Disorders.

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Consultant Offers Tips for Evaluating Staff Pay

MONDAY, March 10, 2014 (HealthDay News) -- Setting salaries and dealing with raises for a practice's staff can be tricky, according to an article published Feb. 24 in Medical Economics.

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Higher Cardiovascular Events Risk After Outbursts of Anger

FRIDAY, March 7, 2014 (HealthDay News) -- There is a heightened risk of cardiovascular events in the hours following an angry outburst, according to research published online March 3 in the European Heart Journal.

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FDA: Pfizer Voluntarily Recalls Certain Lots of Antidepressant

FRIDAY, March 7, 2014 (HealthDay News) -- Two lots of Pfizer's Effexor XR (venlafaxine HCl) are being recalled because they may contain capsules of another drug, Tikosyn (dofetilide), used to treat heart rhythm disorders.

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Women More Sensitive Than Men to Sublingual Zolpidem

FRIDAY, March 7, 2014 (HealthDay News) -- Clearance of zolpidem (administered as a sublingual tablet; ZST) is lower in females compared to males, according to a study published in the March issue of The Journal of Clinical Pharmacology.

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AMA Grants Curriculum Efforts to Address Health Disparities

FRIDAY, March 7, 2014 (HealthDay News) -- Medical schools are beginning to change their curriculum to address ways to eliminate health disparities, according to the American Medical Association (AMA).

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Gender Gap Exists in Domestic Duties of Working Physicians

FRIDAY, March 7, 2014 (HealthDay News) -- Gender differences exist in domestic activities among career-oriented academic physicians with children, according to a study published online March 3 in the Annals of Internal Medicine.

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Relative Value Units Useful In Evaluating Practice Finances

THURSDAY, March 6, 2014 (HealthDay News) -- The Relative Value Unit (RVU) is a useful tool for managing practice finances, according to an article published Feb. 25 in Medical Economics.

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Web-Based Mental Health Screening Feasible, Acceptable

THURSDAY, March 6, 2014 (HealthDay News) -- For patients in general hospital settings, a routine web-based mental health screening is feasible and acceptable, according to a study published in General Hospital Psychiatry.

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Drop in Compensation Gap for Primary Care Docs, Specialists

THURSDAY, March 6, 2014 (HealthDay News) -- From 2012 to 2013, there was a 5.7 percent increase in the median total cash compensation for primary care physicians, with a smaller gap seen for medical and surgical specialists, according to the results of a recent survey from SullivanCotter.

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Yoga May Improve Menopausal Quality of Life

THURSDAY, March 6, 2014 (HealthDay News) -- Yoga may improve menopause-related quality of life (QOL) in women with vasomotor symptoms, according to research published in the March issue of the American Journal of Obstetrics & Gynecology.

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Alzheimer's Disease Deaths May Be More Than Reported

WEDNESDAY, March 5, 2014 (HealthDay News) -- About half a million deaths in the United States may be attributable to Alzheimer's disease (AD), more than five times as many as previously reported and similar to the number of deaths from heart disease and cancer, according to a study published online March 5 in Neurology.

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Value-Based Insurance Plans Can Up Rx Adherence

WEDNESDAY, March 5, 2014 (HealthDay News) -- Value-based insurance design (VBID) plans with certain features aside from solely lowering cost sharing can increase medication adherence, according to a study published in the March issue of Health Affairs.

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Cognitive Behavioral Tx Helpful for Diabetes + Depression

WEDNESDAY, March 5, 2014 (HealthDay News) -- For adults with type 2 diabetes and depression, cognitive behavioral therapy for adherence and depression (CBT-AD) is associated with enduring benefits for diabetes self-management and glycemic control, according to a study published in the March issue of Diabetes Care.

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Community-Based Care Beneficial for Schizophrenia

WEDNESDAY, March 5, 2014 (HealthDay News) -- For patients with schizophrenia, community-based care plus facility-based care is associated with a reduction in symptoms and disability over 12 months, according to a study published online March 5 in The Lancet.

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WHO Program Improves U.S. Medical Facility Hand Hygiene

WEDNESDAY, March 5, 2014 (HealthDay News) -- For U.S. health care facilities, participation in the World Health Organization (WHO) global campaign to improve hand hygiene practices is associated with improved hand hygiene, according to a study published in the March issue of the American Journal of Infection Control.

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Gap in Regulatory Coverage Affects 5 to 16 Percent of Trials

WEDNESDAY, March 5, 2014 (HealthDay News) -- Human subjects protections (HSP) policies do not provide regulatory coverage for all clinical trials, while up to about a quarter of trials are considered overlap trials, according to a research letter published in the March 5 issue of the Journal of the American Medical Association.

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Housing Mobility Interventions Affect Boys, Girls Differently

TUESDAY, March 4, 2014 (HealthDay News) -- Interventions to encourage moving out of high-poverty neighborhoods are associated with increased rates of mental disorders in adolescent boys, but decreased rates of disorders among girls, according to a study published in the March 5 issue of the Journal of the American Medical Association.

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Psychiatric Ills Widespread Among U.S. Soldiers: Studies

TUESDAY, March 4, 2014 (HealthDay News) -- Three new studies suggest that a sizeable percentage of American soldiers suffer from some type of mental health issue, at rates higher than those seen in the general population. The studies were published online March 3 in JAMA Psychiatry.

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Binges Up Risk of Mortality in Older Moderate Drinkers

TUESDAY, March 4, 2014 (HealthDay News) -- Among older moderate drinkers, those who sometimes engage in binge drinking have an increased total mortality risk compared with those who have a regular pattern of moderate drinking, according to research published online March 3 in Alcoholism: Clinical & Experimental Research.

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Women-Specific Research Is Still Inadequate

MONDAY, March 3, 2014 (HealthDay News) -- Women are still underrepresented in medical science and research, and sex differences are often ignored, according to a report published March 3 by the Brigham and Women's Hospital.

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Catastrophizing Can Predict Low Back Pain, Disability

MONDAY, March 3, 2014 (HealthDay News) -- For patients treated for low back pain, catastrophizing may predict the degree of pain and disability, according to a review published in the Feb. 1 issue of Spine.

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Indoor Tanning Common Among High School Students

MONDAY, March 3, 2014 (HealthDay News) -- Indoor tanning is common among high school students and is linked to engaging in other risky behaviors, according to a study published online Feb. 26 in JAMA Dermatology.

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High Rates of Violence for Mentally Ill Adults

MONDAY, March 3, 2014 (HealthDay News) -- Adults with mental illnesses experience violence in the community at high rates, according to a study published online Feb. 13 in the American Journal of Public Health.

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CMS: No More Delays to ICD-10 Implementation Deadline

MONDAY, March 3, 2014 (HealthDay News) -- There will be no more delays to the Oct. 1, 2014, deadline for implementation of the International Classification of Diseases, 10th Revision (ICD-10), according to an article published Feb. 27 in Medical Economics.

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