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SIR: Trellis System Effective for Deep Vein Thrombosis

Registry data suggests that the interventional radiology procedure should be a standard of care

WEDNESDAY, March 19 (HealthDay News) -- In patients with deep vein thrombosis, treatment with the Trellis-8 Peripheral Infusion System removes blood clots and restores blood flow immediately while current catheter-directed thrombolysis can take up to two or three days to be effective and requires hospitalization in an intensive care unit, according to research presented this week at the Society of Interventional Radiology's 33rd Annual Scientific Meeting in Washington, D.C.

Gerard J. O'Sullivan, M.D., of University College Hospital in Galway, Ireland, and a colleague studied commercial registry data on 532 patients with upper and lower extremity deep vein thrombosis who were treated with the Trellis system between February 2005 and August 2007. Among these patients, thrombus chronicity was 28 percent acute, 44 percent acute on chronic, 11 percent sub-acute, 12 percent sub-acute on chronic and 6 percent chronic.

The researchers found that combined Grade II and Grade III lysis were established in 96.8 percent of acute onset of symptoms, 93.6 percent in acute on chronic, 96.7 percent in sub-acute, 89.2 percent in sub-acute on chronic and 90.9 percent with chronic onset of symptoms, and that venous patency was established in all 532 cases. They also found that no adverse events were reported during the acute follow-up period.

"This is a very significant advance in deep vein thrombosis treatment, which hasn't changed in more than 40 years," O'Sullivan said in a statement.

The data presented is from a registry established by the manufacturer of the Trellis device, Bacchus Vascular, Inc.

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