Computer-Aided Detection Improves Cancer Screening

Addition of computer-aided detection to traditional colonography improves efficacy and cost-effectiveness

WEDNESDAY, Feb. 4 (HealthDay News) -- Using computer-aided detection in conjunction with traditional computed tomographic (CT) colonography screening is a cost-effective way to improve colorectal cancer prevention, according to research published in the February issue of Radiology.

Daniele Regge, M.D., of the Institute for Cancer Research and Treatment in Candiolo, Italy, and colleagues evaluated the cost-effectiveness of the addition of computer-aided detection to CT colonography. A Markov-based computer model was used to create a hypothetical population of 100,000 individuals (aged 50 years) who underwent a colorectal screening every 10 years.

When a cost of $50 per CT colonography was attributed to the addition of computer-aided detection, the overall cost increased by only 3 percent to 5 percent, the researchers report. This was mainly due to the profound decreases in colorectal cancer-related costs that occurred with the addition of computer-aided detection. The incremental cost-effectiveness increased when both inexperienced and experienced readers were modeled, although a more profound increase was observed with experienced readers ($8,661 and $61,354, respectively), the report indicates.

"In conclusion, our study shows that the computer-aided detection-related increase in sensitivity for lesions 6 mm or larger renders CT colonography screening both clinically effective and cost-effective for inexperienced and experienced readers, substantially raising the colorectal cancer prevention rate with only a modest increase in program costs," the authors write.

One study author reports financial relationships with the pharmaceutical industry.

Full Text (subscription or payment may be required)

Physician's Briefing