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December 2008 Briefing - Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for December 2008. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Maintenance Drugs Similarly Safe for Vasculitides

THURSDAY, Dec. 25 (HealthDay News) -- In patients with systemic vasculitides such as Wegener's granulomatosis, azathioprine or methotrexate appear to be similarly safe in maintaining remission, according to a report in the Dec. 25 issue of the New England Journal of Medicine.

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Connective Tissue Disease Affects Pregnancy

MONDAY, Dec. 22 (HealthDay News) -- Pregnant women with undifferentiated connective tissue disease have an increased risk of pregnancy complications, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.

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Gene Therapy Reduces Damage from Gum Disease

WEDNESDAY, Dec. 17 (HealthDay News) -- Gene therapy that delivers a soluble form of an anti-inflammatory molecule can prevent bone loss in a rat model of periodontal disease, according to the results of a study published online Dec. 11 in Gene Therapy.

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Grape Component Could Help Alleviate Back Pain

WEDNESDAY, Dec. 10 (HealthDay News) -- A compound found in plants such as grapes can protect intervertebral disc cartilage and reverse cartilage damage, which may have implications for treating disc damage responsible for back pain, according to research published in the Nov. 15 issue of Spine.

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Age, Pathology Affect Natural History of Disc Degeneration

MONDAY, Dec. 8 (HealthDay News) -- New understandings in the natural history of age-related disc degeneration may be relevant to proposed strategies for replenishing disc cells, according to research published in the December issue of Spine.

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Gender May Affect Stem Cell Ability to Repair Cartilage

MONDAY, Dec. 8 (HealthDay News) -- Muscle-derived stem cells (MDSCs) from male mice are more effective than those from female mice in their ability to differentiate into cartilage and repair damaged tissue, according to research published in the December issue of Arthritis & Rheumatism.

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Physician's Briefing
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