Dementia Drug Ineffective for Chronic Fatigue Syndome

Galantamine no more beneficial than a placebo, study finds

TUESDAY, Sept. 7, 2004 (HealthDayNews) -- The drug galantamine, used to treat mild to moderate dementia, is not effective in treating chronic fatigue syndrome, according to a new study.

The research, published in the Sept. 8 issue of the Journal of the American Medical Association, included 434 CFS patients at 35 outpatient centers in western Europe and the United States. The patients were randomly assigned to receive different doses of galantamine or a placebo.

After 16 weeks, there were no statistically significant differences in CFS symptoms between any of the patients.

"The lack of effect of galantamine on cognitive performance was surprising given the extent of the patients' cognitive impairment at baseline," the study authors wrote.

"In conclusion, in this study, galatamine did not provide a significant clinical benefit in the treatment of patients with CFS," they wrote.

More information

The National Center for Infectious Diseases has more about chronic fatigue syndrome.

SOURCE: Journal of the American Medical Association, news release, Sept. 7, 2004
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