Diabetes and Pouch Size Affect Efficacy of Gastric Bypass

Poor weight loss uncommon but diabetics and those with a larger pouch size are more prone

MONDAY, Sept. 15 (HealthDay News) -- Although gastric bypass surgery patients are usually successful in losing weight, those with diabetes or a larger pouch size are more likely than other patients to have disappointing weight loss after surgery, according to a report published in the September issue of the Archives of Surgery.

Guilherme M. Campos, M.D., and colleagues at the University of California San Francisco, analyzed data on 310 patients who underwent gastric bypass surgery from 2003 to 2006. The patients had a preoperative mean body mass index of 52, which dropped to a mean 34 after surgery, due to a mean 60 percent excess weight loss.

Although most patients lost more than 40 percent of their excess weight by the 12-month post-surgery mark, 38 patients (12.3 percent) had poor weight loss, the researchers report. There were four variables associated with poor weight loss, but only diabetes and larger pouch size remained associated with poor weight loss after multivariate analysis, which investigated age, sex, race, marital and insurance status, comorbidities, gastric pouch area and type of surgery, the report indicates.

"Changes in the use of diabetes medications may reduce the risk of poor weight loss among diabetics undergoing gastric bypass surgery," the authors write. "Detailed attention to the creation of a small gastric pouch is essential for achieving the best results."

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