TUESDAY, Dec. 27 (HealthDay News) -- Surgical patients are becoming more vulnerable to perioperative acute thromboembolism syndrome because of the increasing incidence of comorbid conditions, including cardiac and cerebrovascular diseases, metabolic diseases and cancer, according to a study published in the December issue of the Archives of Surgery.
Mutsuhito Kikura, M.D., of the Hamamatsu Medical Center in Hamamatsu, Japan, and colleagues conducted a prospective cohort study of 21,903 surgery patients treated from 1991 through 2002.
Patients with a history of atrial fibrillation, coronary artery disease or diabetes had an increased risk of myocardial infarction. Patients with a history of stroke were more likely to have another stroke, as were those with a history of hyperuricemia. The latter condition and diabetes both increased the risk of death. A history of myocardial infarction was found to increase the risk of deep vein thrombosis, and cancer increased the risk for all types of thromboembolism.
Pre-existing morbidities will increase 1.5-fold in the coming 10 years, and in the same period there will be a threefold increase in thromboembolic events, the researchers estimate. "Our findings underscore the importance of minimizing risk of perioperative acute thromboembolism syndrome arising from comorbid diseases. We hope to reduce its incidence and thereby reduce associated costs as well as improve patient outcomes," the authors conclude.
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