Gastric Banding Tested for Weight Loss in Obese Teens

Laparoscopic banding found to result in higher mean weight loss than lifestyle changes

TUESDAY, Feb. 9 (HealthDay News) -- In a study of obese Australian adolescents, 84 percent who underwent laparoscopic gastric banding lost more than half their excess weight compared to just 12 percent in a lifestyle-intervention program, according to a study in the Feb. 10 issue of the Journal of the American Medical Association.

Paul E. O'Brien, M.D., of the Monash University Medical School in Melbourne, Australia, and colleagues randomized a cohort of 50 teenagers with a body mass index greater than 35 to either gastric banding or a supervised lifestyle intervention of diet, a structured exercise program and behavioral modification. The outcomes included weight loss, adverse events, quality of life, and changes in metabolic syndrome and insulin resistance. The cohort was followed for two years.

The researchers found that 84 percent of the gastric-banding group and 12 percent of the lifestyle-intervention group lost more than 50 percent of excess weight, with mean weight losses of 34.6 kg and 3.0 kg, respectively. After two years, the proportion with metabolic syndrome decreased from 36 to 0 percent in the gastric-banding group and from 40 to 22 percent in the lifestyle group. There were no adverse events in the gastric-banding group; however, 33 percent required follow-up procedures for proximal pouch dilatation or tubing injury.

"Among obese adolescent participants, use of gastric banding compared with lifestyle intervention resulted in a greater percentage achieving a loss of 50 percent of excess weight, corrected for age. There were associated benefits to health and quality of life," the authors conclude.

Allergan supplied the gastric bands for the study. One author reported financial relationships with Allergan and other medical device and pharmaceutical companies.

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