ASRM: Antidepressants May Impair Sperm Quality

SSRIs may affect sperm transport, but effects are reversible

THURSDAY, Oct. 26 (HealthDay News) -- Antidepressants may affect sperm quality, but the effects are reversible, according to two cases reported at the 62nd annual meeting of the American Society for Reproductive Medicine in New Orleans.

Cigdem Tanrikut, M.D., and Peter N. Schlegel, M.D., of New York Hospital/Cornell Medical Center in New York City, report that two male fertility patients had impaired sperm concentration and motility problems while taking antidepressants, but their physical examination and endocrinologic studies were normal. Sperm concentration and mobility normalized once they stopped taking the medications, the study showed.

"Selective serotonin-reuptake inhibitor [SSRI] antidepressants may affect sperm transport, resulting in impaired sperm motility and concentration for some patients," the study authors conclude. "Further controlled studies of the effect of SSRIs on semen parameters are warranted to identify the clinically significant frequency of this effect."


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