Diabetes, Hypertension Risk After Kidney Stone Treatment
Risk higher after shock wave lithotripsy than nonsurgical treatment
WEDNESDAY, April 12 (HealthDay News) -- Patients who undergo shock wave treatment for kidney stones have an almost fourfold higher risk of developing diabetes and 1.5-fold higher risk of hypertension compared with patients managed with medication, according to a study published in the May issue of the Journal of Urology.
Amy E. Krambeck, M.D., and colleagues from the Mayo Clinic in Rochester, Minn., reviewed the charts of 630 patients treated at their institution in 1985 with shock wave lithotripsy using the Dornier HM3 lithotripter for renal and ureteral calculi. They received responses to questionnaires from 288 of these patients in 2004. Patients were compared with a control group matched by age, gender and year of presentation, but whose kidney stones were managed nonsurgically with medication.
The researchers found significantly more hypertension in the surgical group (odds ratio 1.47), which was strongly correlated with bilateral treatment. After controlling for change in body mass index, there was also significantly more diabetes mellitus in the surgical group (odds ratio 3.75), which was related to the total number of shocks administered and the total intensity of treatment.
"At 19 years follow-up, shock wave lithotripsy of renal and proximal ureteral stones was associated with development of hypertension and diabetes mellitus," Krambeck and colleagues conclude.