Pelvic Cooling Technique Beneficial in Prostatectomy

Hypothermic nerve-sparing radical prostatectomy associated with faster return to continence

THURSDAY, April 16 (HealthDay News) -- Hypothermic nerve-sparing radical prostatectomy is a safe and feasible procedure that results in an earlier return to continence, according to a report published in the April issue of Urology.

David S. Finley, M.D., of the University of California-Irvine in Orange, Calif., and colleagues prospectively compared 47 men who underwent preemptive local hypothermia during robotic-assisted laparoscopic prostatectomy (RLP) and 590 men who underwent standard RLP.

The researchers found that men who underwent preemptive local hypothermia during RLP had a significantly faster median return to continence than controls (39 days versus 59 days). After three months, they also found that the zero-pad rate was significantly higher among men who underwent preemptive local hypothermia during RLP (86.8 percent versus 68.6 percent).

"The present study represents the first application of active targeted hypothermia to RLP against secondary inflammatory damage," the authors conclude. "Clearly, additional studies (at multiple centers) are needed to evaluate the depth and duration of hypothermia to confirm our findings and optimize this technique."

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