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April 2006 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for April 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Male Fertility Recovers After Hormonal Contraception

FRIDAY, April 28 (HealthDay News) -- Men who stop using an androgen-containing hormonal contraceptive treatment usually have their fertility recover within four to five months, according to a re-analysis of 15 years' worth of data published in the April 29 issue of The Lancet.

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Periurethral Collagen Injections Help Incontinence

THURSDAY, April 20 (HealthDay News) -- Periurethral collagen injections increase the quality of life for patients with mixed urinary incontinence and may reduce their need for anticholinergic medications, according to a study in the April issue of Urology.

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Camera Phone Can Boost Urology Practice Functions

THURSDAY, April 20 (HealthDay News) -- Pictures taken with a camera phone can improve the function of a urology practice, allowing secure Internet transmission, instant storage and the addition of office notes, according to a study in the April issue of Urology.

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Tolterodine Can Relieve Overactive Bladder Micturitions

THURSDAY, April 20 (HealthDay News) -- Tolterodine extended release (TER) taken four hours or less before bed helps reduce nighttime micturitions due to overactive bladder, according to a study in the April issue of Urology.

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Researchers Develop Model to Predict Prostate Cancer Risk

WEDNESDAY, April 19 (HealthDay News) -- Researchers have developed a model that can be used to predict prostate cancer risk based on prostate-specific antigen (PSA) levels, family history, race and other factors, according to a study in the April 19 issue of the Journal of the National Cancer Institute. The model suggests that men who are black, have an older age at biopsy, higher PSA and an abnormal digital rectal exam result are more likely to have high-grade disease.

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Sperm Retrieval More Costly During Vasectomy Reversal

FRIDAY, April 14 (HealthDay News) -- Sperm retrieval and cryopreservation is not cost-effective when conducted during surgery to reverse a vasectomy, according to a report in the April issue of Fertility and Sterility. Instead, it is more cost effective to harvest sperm at the time of in vitro fertilization from patients who are still azoospermic after the reversal procedure, the authors say.

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Homocysteine Not Tied to Peripheral Arterial Disease

FRIDAY, April 14 (HealthDay News) --The apparent association between homocysteine and peripheral arterial disease can be explained by confounding factors such as smoking, lead and cadmium exposure, and renal function, according to a study in the April 15 issue of the American Journal of Epidemiology.

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Expectant Management An Option For Bile Stones

THURSDAY, April 13 (HealthDay News) -- Expectant management after endoscopic retrograde cholangiography with sphincterotomy (ERC-S) for common bile duct stones may be a reasonable strategy in elderly patients, but it depends on the probability of recurrent symptoms, according to a study in the April issue of the American Journal of Gastroenterology.

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Renal Insufficiency Predicts Appropriate ICD Shocks

THURSDAY, April 13 (HealthDay News) -- Because renal insufficiency is a strong predictor of appropriate implantable cardioverter defibrillator (ICD) shocks, patients with renal insufficiency should not be excluded from ICD therapy, according to a study published in the April issue of the American Heart Journal.

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Burch Colposuspension Reduces Stress Incontinence

WEDNESDAY, April 12 (HealthDay News) -- In women without stress incontinence who undergo abdominal sacrocolpopexy for prolapse, Burch colposuspension significantly reduces the risk of postoperative stress incontinence, according to a study in the April 13 issue of the New England Journal of Medicine.

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Diabetes, Hypertension Risk After Kidney Stone Treatment

WEDNESDAY, April 12 (HealthDay News) -- Patients who undergo shock wave treatment for kidney stones have an almost fourfold higher risk of developing diabetes and 1.5-fold higher risk of hypertension compared with patients managed with medication, according to a study published in the May issue of the Journal of Urology.

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High Cholesterol Linked to Prostate Cancer

WEDNESDAY, April 12 (HealthDay News) -- Men with hypercholesterolemia may have a higher risk of prostate cancer, according to a case-control study published online April 12 in the Annals of Oncology.

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Prostate-Specific Nanoparticles Shrink Tumors in Mice

TUESDAY, April 11 (HealthDay News) -- Researchers have developed prostate-specific nanoparticles that can deliver docetaxel to prostate cells, and the nanoparticles completely reduced tumors in 5 of 7 mice treated with the experimental therapy, according to a report published online April 10 in the Proceedings of the National Academy of Sciences Early Edition.

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Acidic Urine Linked to Nephrolithiasis in Diabetics

MONDAY, April 10 (HealthDay News) -- Low urine pH may be the reason why type 2 diabetics are at greater risk of forming uric acid kidney stones, according to a study published in the April issue of the Journal of the American Society of Nephrology.

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Engineered Bladders Promising in First Clinical Trial

TUESDAY, April 4 (HealthDay News) -- New bladders engineered from a patient's own cells grown on a biodegradable scaffold have been implanted in 7 myelomeningocele patients who normally would have undergone intestinal cystoplasty due to end-stage bladder disease, according to a report published online April 4 in The Lancet.

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Folic Acid Fails to Improve Chronic Renal Failure Outcomes

MONDAY, April 3 (HealthDay News) -- In patients with chronic renal failure, high-dose folic acid does not slow the progression of atherosclerosis or reduce cardiovascular events, according to a study published March 21 in the Journal of the American College of Cardiology.

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