August 2006 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for August 2006. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Genome Mapping Links Region to Prostate Cancer in Blacks

THURSDAY, Aug. 31 (HealthDay News) -- Researchers have identified a region on chromosome 8q24 that is significantly associated with prostate cancer risk in African American men, according to a study published online Aug. 31 in the Proceedings of the National Academy of Sciences Early Edition.

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Low Inhibin B Levels Linked to Male Infertility

THURSDAY, Aug. 31 (HealthDay News) -- The dimeric hormone inhibin B may be a more sensitive marker of spermatogenesis than follicle stimulating hormone (FSH) or luteinizing hormone, according to a study published in the August issue of Fertility and Sterility.

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Bone Metastases Infrequent in New Prostate Cancer Cases

TUESDAY, Aug. 29 (HealthDay News) -- In newly diagnosed prostate cancer patients, bone metastases are uncommon, according to a study published in the August issue of Urology.

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Nephropathy Less Likely With Isosmolar Contrast Media

TUESDAY, Aug. 29 (HealthDay News) -- Isosmolar contrast media iodixanol is associated with a significantly lower risk of contrast-induced nephropathy than low-osmolar contrast media, according to a study published in the Aug. 15 issue of the Journal of the American College of Cardiology.

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Racial Disparity Seen in Kidney Cancer Survival

MONDAY, Aug. 28 (HealthDay News) -- Even in clinical trials where patients have similar characteristics and receive the same treatments, blacks with metastatic renal cell carcinoma have a significantly shorter survival time than their white counterparts, according to the results of a study published in the August issue of Urology.

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Subclinical Inguinal Hernias Up Risk for RPRIH

MONDAY, Aug. 28 (HealthDay News) -- Subclinical inguinal hernias may predict the development of radical prostatectomy-related inguinal hernia (RPRIH) within a year of undergoing surgery, and patients with these subclinical hernias should undergo hernia repair surgery during prostatectomy, according to research in the August issue of Urology.

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CT Scans May Overestimate Renal Tumor Size

THURSDAY, Aug. 24 (HealthDay News) -- Preoperative computed tomography (CT) scans may slightly overestimate the pathologic size of certain renal tumors, according to a study published in the August issue of Urology.

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Three Signs Suggest Rare Renal Tumor in Young Adults

THURSDAY, Aug. 24 (HealthDay News) -- Physicians should consider renal peripheral primitive neuroectodermal tumor (PNET) in young adults who present with the classic triad of renal cancer, hematuria, and pain and palpable tumor, according to three case studies and a corresponding literature review in the August issue of Urology.

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Signs of Interstitial Cystitis Can Change in Young Women

THURSDAY, Aug. 24 (HealthDay News) -- A negative hydrodistension in young women may not necessarily exclude the presence of interstitial cystitis because the cystoscopic appearance of the bladder wall can change over time, according to a study published in the August issue of Urology.

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PSA Can Predict Benefit From Radical Prostatectomy

THURSDAY, Aug. 24 (HealthDay News) -- In men with high-grade prostate cancer, prostate specific antigen (PSA) values and percent positive biopsy cores may predict who is most likely to benefit from radical prostatectomy, according to a study in the August issue of Urology.

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Liver, Kidney Transplant Best for Dual-Organ Disease

WEDNESDAY, Aug. 23 (HealthDay News) -- Combined liver and kidney transplant benefits patients with dual-organ disease, including those with hepatorenal syndrome who have been receiving dialysis for more than two months, according to a study in the August issue of Archives of Surgery.

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Snoring Associated With Nocturnal Enuresis in Children

WEDNESDAY, Aug. 23 (HealthDay News) -- Children who snore more than three nights per week are nearly four times as likely to have nocturnal enuresis as those who do not habitually snore, according to a study published in the August issue of Urology.

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U.S. Prevalence of Herpes Simplex Virus Type 2 Decreasing

TUESDAY, Aug. 22 (HealthDay News) -- The seroprevalence of herpes simplex virus type 2 (HSV-2), the primary cause of genital herpes, has significantly declined since the late 1980s and early 1990s in the United States, especially among teenagers, according to a study in the Aug. 23/30 issue of the Journal of the American Medical Association.

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Cystatin C Predicts Adverse Outcomes in Elderly

FRIDAY, Aug. 18 (HealthDay News) -- A marker of kidney function, cystatin C, predicts the risk of death, cardiovascular disease and chronic kidney disease better than creatinine in the elderly, according to a report in the Aug. 15 issue of the Annals of Internal Medicine.

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Editorial

Finasteride May Improve Sensitivity of PSA Test

THURSDAY, Aug. 17 (HealthDay News) -- Results from the prostate-specific antigen (PSA) test are more accurate among men who are being treated with the drug finasteride, according to a study published in the Aug. 16 issue of the Journal of the National Cancer Institute.

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Socioeconomic Status Linked to Late-Life Disability

THURSDAY, Aug. 17 (HealthDay News) -- While the link between extreme poverty and poor health has long been recognized, a new report in the Aug. 17 New England Journal of Medicine extends the socioeconomic disparity to functional limitation and disability later in life.

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Defib Implant May Not Benefit Renal Failure Patients

WEDNESDAY, Aug. 16 (HealthDay News) -- Implantable cardioverter defibrillator therapy may not benefit high-risk cardiac patients with advanced renal dysfunction, according to a retrospective analysis published in the Aug. 15 issue of the American Journal of Cardiology.

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Early Prostate Cancer Detection Linked to Overtreatment

WEDNESDAY, Aug. 16 (HealthDay News) -- Men in the United States with early-stage prostate cancer are often subjected to unnecessary prostatectomy and radiation therapy in place of more appropriate care such as expectant management, according to a study published Aug. 16 in the Journal of the National Cancer Institute.

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Low Testosterone Level Raises Mortality Risk for Men

MONDAY, Aug. 14 (HealthDay News) -- Men with low levels of testosterone after the age of 40 are at higher risk of death than their counterparts with normal levels of the hormone, according to a study published in the August 14/28 issue of the Archives of Internal Medicine.

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Heart Patients Should Be Tested for Chronic Kidney Disease

MONDAY, Aug. 7 (HealthDay News) -- All patients with or at risk for cardiovascular disease should be given a simple blood or urine test that can detect chronic kidney disease, according to an advisory from the American Heart Association and the National Kidney Foundation published online Aug. 7 in Circulation: Journal of the American Heart Association.

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Incontinence in First Pregnancy Linked to Risk Later in Life

THURSDAY, Aug. 3 (HealthDay News) -- Women with stress urinary incontinence during a first pregnancy or shortly after giving birth are at increased risk of having stress incontinence 12 years later, according to a report in the Aug. 1 issue of Obstetrics & Gynecology.

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Dead Donors Are a Source of Transplantable Kidneys

WEDNESDAY, Aug. 2 (HealthDay News) -- The graft survival rates of transplanted kidneys from donors who died due to an out-of-hospital cardiac arrest are as good as those from heart-beating kidney donors who are younger than age 60, according to a study published in the Aug. 1 issue of the Annals of Internal Medicine.

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Primary Care Physicians May Miss Chronic Kidney Disease

WEDNESDAY, Aug. 2 (HealthDay News) -- Many primary care physicians (PCPs) may not properly diagnose and refer patients with chronic kidney disease, according to a study in the August issue of the American Journal of Kidney Diseases, in which "mock" patients' symptoms were presented for diagnosis.

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Higher Blood Pressure Seen in Kidney Donors

TUESDAY, Aug. 1 (HealthDay News) -- Kidney donors may experience a higher blood pressure increase in the five to 10 years following donation than would be expected with normal aging, according to a meta-analysis published in the Aug. 1 issue of the Annals of Internal Medicine.

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Physician's Briefing