Here are what the editors at HealthDay consider to be the most important developments in Urology for December 2008. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
New Drug Approved for Prostate Cancer
TUESDAY, Dec. 30 (HealthDay News) -- Degarelix was recently approved by the U.S. Food and Drug Administration for the treatment of advanced prostate cancer, making it the first new drug approved for this indication in the past several years, according to a Dec. 29 FDA news release.
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Imaging Combo Increases Prostate Cancer Detection
MONDAY, Dec. 29 (HealthDay News) -- Combining an apparent diffusion coefficient map reading with T2-weighted MRIs improves their diagnostic capability for prostate cancer detection, according to research published in the January issue of Radiology.
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High-Risk Prostate Cancer Seen in Many Low-Income Men
FRIDAY, Dec. 19 (HealthDay News) -- Underdetection and undertreatment of prostate cancer may be a particular problem in men with low incomes, and these men may be more likely to present with incurable disease, according to research released online Dec. 16 in advance of publication in the February issue of the Journal of Urology.
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Testosterone Undecanoate Benefits Hypogonadal Men
FRIDAY, Dec. 19 (HealthDay News) -- In men with hypogonadism, intramuscular injection of long-acting testosterone undecanoate results in a sustained, consistent serum testosterone in the normal range, researchers report in the December issue of the Journal of Urology.
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Ureteroscopy Safe for Stone Removal in Pregnancy
THURSDAY, Dec. 18 (HealthDay News) -- In pregnant women with obstructing ureteral calculi refractory to conservative treatment, ureteroscopy is a safe and reasonable treatment, researchers report in the January issue of the Journal of Urology.
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Gene Variant Predicts Adverse Reaction to Chemotherapy
THURSDAY, Dec. 18 (HealthDay News) -- In patients with advanced urinary-tract cancers, a polymorphism of the CYP3A5 gene may predict the severity of leukocytopenia caused by standard chemotherapy treatments, according to study findings published in the December issue of the Journal of Urology.
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Radiation Addition Improves Survival in Prostate Cancer
TUESDAY, Dec. 16 (HealthDay News) -- Adding radiotherapy to hormonal treatment improves survival in men with locally advanced prostate cancer, according to research published online Dec. 16 in The Lancet.
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Fitness Training Improves Fatigue in Prostate Cancer
THURSDAY, Dec. 11 (HealthDay News) -- Fitness training, particularly resistance training, can reduce fatigue and improve quality of life in men with prostate cancer undergoing radiation treatment, according to research published online Dec. 8 in the Journal of Clinical Oncology.
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Fear of Prostate Cancer Return Linked to Mental Health
WEDNESDAY, Dec. 10 (HealthDay News) -- Fear of recurrence, along with treatment-related symptoms, affect quality of life in prostate cancer survivors, according to research published in the December issue of Urology.
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Vitamin D Growth Inhibition of Prostate Cancer Explained
WEDNESDAY, Dec. 10 (HealthDay News) -- The ability of vitamin D to block the growth of prostate cancer can be partially explained by its activation of Mullerian inhibiting substance (MIS), according to a report published online Dec. 4 in Endocrinology.
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Long-Term Antioxidant Use Does Not Prevent Cancer
TUESDAY, Dec. 9 (HealthDay News) -- Antioxidant supplementation, specifically with selenium or vitamins C and E, has no role in cancer prevention, according to results of two separate studies published online Dec. 9 in the Journal of the American Medical Association.
Abstract - Gaziano
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Abstract - Lippman
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NSAIDs Are Safe, Effective for Prostatectomy Pain
TUESDAY, Dec. 9 (HealthDay News) -- The use of non-steroidal anti-inflammatory drugs (NSAIDs) appears to be safe and effective for pain relief following radical retropubic prostatectomy, according to research published in the December issue of Urology.
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Classes After Prostate Cancer Linked to Dietary Changes
MONDAY, Dec. 8 (HealthDay News) -- Cooking classes focused on a plant-based diet can encourage prostate cancer survivors to eat a more prostate-healthy diet, according to research published in the December issue of Urology.
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Psychosocial Factors Affect Prostate Cancer Screening
MONDAY, Dec. 8 (HealthDay News) -- In middle-aged and older men, decisions about prostate cancer screening may be strongly influenced by factors such as family history of prostate cancer, marital status and worry over developing the disease, researchers report in the December issue of Cancer Epidemiology, Biomarkers & Prevention.
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Discontinuation Rate for Bladder Medications High
MONDAY, Dec. 1 (HealthDay News) -- More than half of women prescribed anticholinergic drugs for lower urinary tract symptoms suggestive of overactive bladder discontinued treatment after six months, suggesting poor adherence to treatment, researchers report in the December issue of Obstetrics & Gynecology.
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