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June 2008 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for June 2008. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Gastric Bypass May Raise Risk of Kidney Stones

MONDAY, June 30 (HealthDay News) -- Morbidly obese patients who undergo Roux-en-Y gastric bypass are at risk of developing kidney stones as early as three months after surgery, researchers report in the June issue of the Journal of the American College of Surgeons.

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Video May Help Trim Sexually Transmitted Disease Rates

THURSDAY, June 26 (HealthDay News) -- New infections among patients at sexually transmitted disease (STD) clinics can be reduced by up to 10 percent by showing a brief educational video in the waiting room, according to an article published in the June issue of PLoS Medicine.

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Haplotype Blocks in 8q24 Gene Desert Linked to Cancer

WEDNESDAY, June 25 (HealthDay News) -- Five specific loci within the 8q24 gene desert are associated with an increased risk of various cancers, according to research published in the July 2 issue of the Journal of the National Cancer Institute.

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Article Examines Use of 'Key Opinion Leaders' in Drug Sales

FRIDAY, June 20 (HealthDay News) -- Influential doctors known as "key opinion leaders" are paid generous fees to influence their peers to prescribe a company's drugs and may in fact be considered salespeople by the industry, according to an article in the June 21 issue of BMJ.

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Editorial - Buckwell
Editorial - Fava

Lifestyle Changes Lead to Benefits in Prostate Cancer

WEDNESDAY, June 18 (HealthDay News) -- Men with low-risk prostate cancer who undertake an intensive nutrition and lifestyle intervention have beneficial changes at the molecular level in the prostate, according to the results of a study in the June 17 issue of the Proceedings of the National Academy of Sciences.

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Salvage Radiation Improves Prostate Cancer Survival Time

TUESDAY, June 17 (HealthDay News) -- In men with a recurrence of prostate cancer and a prostate-specific antigen doubling time of less than six months, salvage radiation can increase disease-specific survival, according to a report published in the June 18 issue of the Journal of the American Medical Association.

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SPINK1 Implicated in Prostate Cancer Aggressiveness

FRIDAY, June 13 (HealthDay News) -- The oncogene SPINK1 is a biomarker detectable in urine that's associated with prostate cancer aggressiveness, with outlier expression identified only in a subset of ETS-negative cancers, researchers report in the June issue of Cancer Cell.

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Cancer Costs Increasing Due to More Treatment

WEDNESDAY, June 11 (HealthDay News) -- The costs associated with treating cancer in the elderly have largely increased due to more patients receiving surgery and adjuvant treatment, and rising prices for these therapies, researchers report in the June 18 issue of the Journal of the National Cancer Institute.

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Urology Residency Interview Process Can Be Costly

TUESDAY, June 10 (HealthDay News) -- For recent medical school graduates, the cost of interviewing for urology residency programs is substantial and could prevent some qualified applicants from reaching their full potential, according to an article published in the June issue of Urology.

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Nocturia Linked to Sleep Apnea in Younger Men

MONDAY, June 9 (HealthDay News) -- Nocturia -- defined as two or more voidings per night -- may be associated with obstructive sleep apnea in men younger than age 50, according to the results of a study published in the June issue of Urology.

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Needle Guide Type Affects Prostate Biopsy Complications

MONDAY, June 9 (HealthDay News) -- In men undergoing transrectal prostate biopsy, the use of a disposable ultrasound needle guide may significantly reduce the rate of infectious complications, according to research published in the June issue of Urology.

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Castration-Resistant Prostate Cancer Mechanism Proposed

TUESDAY, June 3 (HealthDay News) -- Metastatic prostate cancers may adapt to low systemic testosterone levels and maintain intratumoral androgens by modulating enzymes involved in intracrine steroidogenesis and androgen catabolism. This mechanism may explain why nearly all patients eventually develop castration-resistant disease despite anorchid serum androgen levels, researchers report in the June 1 issue of Cancer Research.

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Study Sheds Light on Role of T3 in Male Rat Reproduction

MONDAY, June 2 (HealthDay News) -- Researchers have found expression of iodothyronine 5'-deiodinase (5'-D), an enzyme that creates the active form of triiodothyronine (T3) from thyroxine (T4), in several tissues in the male reproductive tract, according to study findings released online May 8 in advance of publication in Endocrinology. These findings may help shed light on the poorly understood role of thyroid hormones in regulating reproductive function in reproduction organs other than gonads.

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Tomato Ingredient May Offer Prostate Protection

MONDAY, June 2 (HealthDay News) -- The ketosamine FruHis, found in tomato powder, may interact with lycopene to offer protection against prostate cancer, according to research from rat studies published in the June 1 issue of Cancer Research.

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Physician's Briefing
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