June 2010 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for June 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Group of Older Men Have Cardio Events With Testosterone Gel

WEDNESDAY, June 30 (HealthDay News) -- Older men with limited mobility have improved muscle strength but an increased risk of cardiovascular events when they receive testosterone gel supplementation, according to research published online June 30 in the New England Journal of Medicine.

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Statins May Slow Post-Surgery Cancer Recurrence

TUESDAY, June 29 (HealthDay News) -- In men who undergo radical prostatectomy for prostate cancer, those who take statins have a decreased risk of biochemical recurrence, according to research published online June 28 in Cancer.

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Doctors Agree Malpractice Fears Drive Overuse of Tests

MONDAY, June 28 (HealthDay News) -- A large majority of physicians agree that the practice of defensive medicine -- stemming from malpractice concerns -- is responsible for an overuse of medical tests and procedures, according to a research letter in the June 28 issue of the Archives of Internal Medicine.

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Insecticide Exposure May Increase Prostate Cancer Risk

FRIDAY, June 25 (HealthDay News) -- Exposure to the estrogenic insecticide chlordecone is associated with an increased risk of prostate cancer, according to a study published online June 21 in the Journal of Clinical Oncology.

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Active Surveillance Sound Approach to Prostate Cancer

FRIDAY, June 25 (HealthDay News) -- Active surveillance appears to be a sound approach to managing prostate cancer with a favorable risk profile, according to a review published in the July issue of The Journal of Urology.

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Cytology Limits Seen in Low-Risk Patients With Hematuria

THURSDAY, June 24 (HealthDay News) -- During evaluation of low-risk patients with asymptomatic microscopic hematuria (AMH), voided urine cytology is associated with a substantial cost without providing a diagnostic benefit, according to research published in the June issue of Urology.

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Prostate Cancer Endocrine Treatment Increases CVD Risk

THURSDAY, June 24 (HealthDay News) -- Men with prostate cancer who receive endocrine treatment (ET) have a modest increase in risk for cardiovascular disease (CVD), suggesting that clinicians should consider CVD risk when prescribing this treatment, according to a study published online June 21 in the Journal of Clinical Oncology.

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Watchful Waiting May Suffice in Low-Risk Prostate Cancer

MONDAY, June 21 (HealthDay News) -- For patients with prostate cancer that has a low risk of progression, active surveillance is associated with a low death rate, suggesting that it may be a sufficient management approach, according to research published online June 18 in the Journal of the National Cancer Institute.

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Jevtana Approved for Advanced Prostate Cancer

THURSDAY, June 17 (HealthDay News) -- The chemotherapy drug Jevtana (cabazitaxel) has been approved by the U.S. Food and Drug Administration to treat advanced prostate cancer that worsens despite use of a standard drug therapy, docetaxel.

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Strict Diagnostic Criteria Define Late-Onset Hypogonadism

WEDNESDAY, June 16 (HealthDay News) -- Using a concise definition of late-onset hypogonadism which includes the presence of specific sexual symptoms as well as a strict laboratory testosterone level cut-point in older men can identify those men who truly need testosterone replacement therapy, according to research published online June 16 in the New England Journal of Medicine.

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Obesity Has Negative Impacts on Sexual Health, Behavior

WEDNESDAY, June 16 (HealthDay News) -- Obesity has negative impacts on sexual health in both men and women, and young obese women are less likely to use contraceptive health care services and more likely to have unplanned pregnancies, according to a study published June 15 in BMJ.

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After Vasectomy, One Sample May Be Enough for Clearance

MONDAY, June 14 (HealthDay News) -- Providing clearance to vasectomy patients who have provided just one semen sample containing less than 100,000 immotile sperm/mL at least three months after the procedure is safe and greatly reduces the number of men who cannot be cleared, according to a study in the June issue of BJU International, the journal of the British Association of Urological Surgeons.

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Enhancing Red Blood Cells in Prostatectomy Judged Safe

MONDAY, June 14 (HealthDay News) -- The use of erythropoietin stimulating proteins (ESPs) in men with normal hemoglobin levels undergoing open radical retropubic prostatectomy is not associated with an increase in cardiovascular or thromboembolic complications, according to a study in the June issue of Urology.

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Node Removal Count Impacts Testicular Cancer Recurrence

FRIDAY, June 11 (HealthDay News) -- The number of retroperitoneal lymph nodes removed and analyzed in post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) appears to be a significant predictor of testicular cancer recurrence, according to research published in the June issue of Urology.

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Increasing BMI Linked to Several Nephrolithiasis Risk Factors

FRIDAY, June 11 (HealthDay News) -- Increasing body mass index (BMI) is associated with the presence of several urinary stone risk factors in the urine chemistry, suggesting that weight loss should be part of a urinary stone prevention regimen, according to a study in the June issue of Urology.

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Stage IV Prostate Cancer Incidence Down, Survival Up

FRIDAY, June 11 (HealthDay News) -- In recent decades, stage IV prostate cancer incidence has significantly declined and survival has improved, but younger men represent an increasing proportion of those diagnosed, according to research published in the June issue of Urology.

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Organ Sparing Surgery for Bladder Cancer Feasible

THURSDAY, June 10 (HealthDay News) -- Gynecologic organ sparing procedures for the surgical treatment of bladder cancer appear to be feasible, with acceptable oncologic outcomes and voiding function, according to research published in the June issue of Urology.

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Fatal Medication Errors Rise in July at Teaching Hospitals

TUESDAY, June 8 (HealthDay News) -- In July there is a significant increase in fatal medication errors at medical institutions, and this spike is at least partly due to the arrival of new medical residents, according to a study published online May 29 in the Journal of General Internal Medicine.

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Many Men Disagree With No-PSA-at-75 Recommendation

THURSDAY, June 3 (HealthDay News) -- A U.S. Preventive Services Task Force (USPSTF) recommendation to discontinue prostate-specific antigen (PSA) screening at age 75 is not supported by many men, and men ages 75 and older show higher-risk disease and poorer survival, according to research published in the May issue of Urology.

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Non-Dairy Calcium May Up Risk of Prostate Cancer

TUESDAY, June 1 (HealthDay News) -- Calcium intake, even from non-dairy sources and at relatively low levels, may put Chinese men, particularly those with a low body mass index, at increased risk of prostate cancer, according to research published online June 1 in Cancer Research.

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