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June 2011 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for June 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Silodosin Found to Reduce Chronic Prostatitis Symptoms

WEDNESDAY, June 29 (HealthDay News) -- Silodosin may provide symptomatic relief and improve quality of life for patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), according to a study published in the July issue of The Journal Of Urology.

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New Drug Targets Found for Benign Prostatic Hyperplasia

THURSDAY, June 23 (HealthDay News) -- Novel drug targets, including muscarinic receptor or P2X1-purinoceptor antagonists, are potentially effective treatment options for benign prostatic hyperplasia (BPH), according to a review published online June 8 in the British Journal of Pharmacology.

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Statin Therapy Tied to Lower Prostate Cancer Risk

THURSDAY, June 23 (HealthDay News) -- Statin therapy may decrease the risk and severity of prostate cancer, according to a study published in the July issue of The Journal of Urology.

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Syndrome Caused by E. coli Mostly in Adults, Women

WEDNESDAY, June 22 (HealthDay News) -- A large, ongoing outbreak of the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli (E. coli) in Germany is occurring mostly in adults, primarily women, according to a study published online June 22 in the New England Journal of Medicine.

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Smoking Tied to Prostate Cancer Mortality, Recurrence

TUESDAY, June 21 (HealthDay News) -- Men who are smokers at the time of prostate cancer diagnosis have an increased risk of total mortality, cardiovascular disease (CVD) mortality, prostate cancer mortality, and recurrence, according to a study published in the June 22/29 issue of the Journal of the American Medical Association.

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Generic Versions of Levofloxacin Approved

MONDAY, June 20 (HealthDay News) -- The first generic versions of levofloxacin, prescribed under the brand name Levaquin, have been approved by the U.S. Food and Drug Administration.

National Library of Medicine

FDA: Diabetes Drug May Up Risk of Bladder Cancer

THURSDAY, June 16 (HealthDay News) -- The U.S. Food and Drug Administration has warned consumers and health care professionals that pioglitazone (Actos) may increase the risk of bladder cancer when used for more than one year.

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Nulojix Approved to Help Thwart Kidney Rejection

THURSDAY, June 16 (HealthDay News) -- Nulojix (belatacept) has been approved by the U.S. Food and Drug Administration to prevent rejection of a transplanted kidney in adults.

kidney transplant

Unequal Care Access for Children With Public Insurance

THURSDAY, June 16 (HealthDay News) -- Access to outpatient care is restricted for children with public insurance compared to those with private insurance, according to a study published in the June 16 issue of the New England Journal of Medicine.

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Life Expectancy in U.S. Counties Below Many Nations

WEDNESDAY, June 15 (HealthDay News) -- Most counties within the United States fall behind the international frontier with the best life expectancies in the world, according to a study published online June 15 in Population Health Metrics.

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Similar Number for Outpatient, Inpatient Malpractice Claims

TUESDAY, June 14 (HealthDay News) -- The number of paid malpractice claims is similar in both inpatient and outpatient settings, according to a study published in the June 15 issue of the Journal of the American Medical Association.

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Urinary Urgency Tied to Nocturia in Interstitial Cystitis

FRIDAY, June 10 (HealthDay News) -- In patients with interstitial cystitis/painful bladder syndrome (IC/PBS), urinary urgency is correlated with the presence and severity of nocturia, and bladder pain is correlated with the severity of nocturia, according to a study published in the June issue of Urology.

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Prostate Drugs Undergo Label Revision Due to Cancer Risk

THURSDAY, June 9 (HealthDay News) -- Drugs in the class of 5-alpha reductase inhibitors (5-ARIs), which includes finasteride and dutasteride, have undergone a label change to reflect current safety information concerning an increased risk of high-grade prostate cancer, the U.S. Food and Drug Administration has announced.

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Transvaginal Mesh Surgery Restores Pelvic Organ Prolapse

THURSDAY, June 9 (HealthDay News) -- Transvaginal mesh (TVM) surgery is effective in treating pelvic organ prolapse (POP) in both pre- and postmenopausal women but dyspareunia may worsen in premenopausal women, according to a study published online May 23 in the Journal of Sexual Medicine.

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VHA System in United States Provides Better Cancer Care

WEDNESDAY, June 8 (HealthDay News) -- The Veterans Health Administration (VHA) system in the United States provides similar or better care for older men with cancer than fee-for-service Medicare, although some new technologies are less available, according to a study published in the June 7 issue of the Annals of Internal Medicine.

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Youth Bear Large Burden of Global Death, Disease

TUESDAY, June 7 (HealthDay News) -- Youths between the ages of 10 and 24 years carry 15.5 percent of the global burden of disability-adjusted life-years (DALYs), according to a study published online June 7 in The Lancet.

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Efficacy of Radiation Therapy for Prostate Cancer Unclear

TUESDAY, June 7 (HealthDay News) -- Current evidence is inconclusive regarding the efficacy of radiation treatment compared to no treatment for localized prostate cancer, according to a review published online June 6 in the Annals of Internal Medicine.

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Molecular Mechanisms of Priapism Identified

FRIDAY, June 3 (HealthDay News) -- Recent advances have identified several molecular mechanisms, which may play a role in sickle cell disease-associated priapism, according to a review published online May 6 in The Journal of Sexual Medicine.

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Post-Chemo Cystectomy for Bladder Cancer OK at 10 Weeks

THURSDAY, June 2 (HealthDay News) -- Cystectomy delivered within 10 weeks after neoadjuvant chemotherapy (NAC) does not compromise survival of patients with muscle-invasive bladder cancer (MIBC), according to a study published online May 19 in Cancer.

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Murine Viruses Not Linked to Human Infection

WEDNESDAY, June 1 (HealthDay News) -- Murine-like gammaretroviruses (MLVs), including xenotropic murine leukemia virus-related virus (XMRV), are unlikely to cause either prostate cancer or chronic fatigue syndrome (CFS) in humans, and their detection in human beings is likely due to sample contamination, according to two studies published online May 31 in Science.

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Physician's Briefing
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