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November 2007 Briefing - Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for November 2007. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Study Reports Risk Factors for Postoperative Renal Failure

THURSDAY, Nov. 29 (HealthDay News) -- Intraoperative vasopressor and diuretic use are independent predictors of postoperative acute renal failure in patients with previously normal renal function who undergo non-cardiac surgery, and those who develop acute renal failure have worsened short- and long-term mortality, according to research published in the December issue of Anesthesiology.

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Galvanotherapy Safe, Effective in Prostate Cancer

THURSDAY, Nov. 29 (HealthDay News) -- MRI-guided galvanotherapy, a therapeutic modality that applies a direct current to tumor tissue, is well-tolerated and effective in reducing tumor burden in patients with prostate cancer, according to research published in the December issue of Radiology.

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High-Carbohydrate Diet Promotes Cancer Growth in Mice

WEDNESDAY, Nov. 28 (HealthDay News) -- A high-carbohydrate/high-fat diet promotes tumor growth in a mouse model of prostate cancer more than a low-carbohydrate/high-fat diet, according to study findings published online Nov. 27 in the Journal of the National Cancer Institute.

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BRCA1 and BRCA2 Mutations Linked to Male Breast Cancer

WEDNESDAY, Nov. 28 (HealthDay News) -- Men who carry germline mutations in the BRCA1 and BRCA2 genes have a higher risk of developing breast cancer than non-carriers, according to research published online Nov. 27 in the Journal of the National Cancer Institute.

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Microarray Analysis Offers Clues to Kidney Rejection

TUESDAY, Nov. 27 (HealthDay News) -- In a human study utilizing microarray analysis, pathogenesis-based transcript sets annotated from mouse transplants and cell cultures offered a means to measure inflammatory disturbances that lead to organ rejection after kidney transplantation, and may shed light on the mechanism of rejection, according to a study published in the December issue of the American Journal of Transplantation.

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Doctors and Patients Have Different Perception of Herpes

MONDAY, Nov. 26 (HealthDay News) -- Although patients with genital herpes and their doctors have similar attitudes toward some aspects of the disease, they also have very different perspectives on treatment and management, according to a study published online Nov. 22 in the journal Sexually Transmitted Infections.

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'Mismatch' Treatments Affect Outcomes in Prostate Cancer

MONDAY, Nov. 26 (HealthDay News) -- A significant number of prostate cancer patients receive "mismatch" treatments that aggravate pre-existing conditions when alternate treatment options might have avoided those problems and improved outcomes, according to a report published online Nov. 26 in the journal Cancer.

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Obesity Linked to Reduced PSA Concentrations

TUESDAY, Nov. 20 (HealthDay News) -- Obese men undergoing radical prostatectomy have a higher plasma volume than their normal weight counterparts, suggesting that hemodilution may be responsible for the lower serum prostate-specific antigen (PSA) concentrations observed in obese versus normal weight men, according to study results published in the Nov. 21 issue of the Journal of the American Medical Association.

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Men in 40s Less Interested in PSA Testing Than Older Men

FRIDAY, Nov. 16 (HealthDay News) -- Men between the ages of 45 and 49 accept invitations for prostate cancer screening at a much lower rate than older men, according to research published Nov. 15 in BMJ Online First.

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Weight Affects Prostate Cancer Mortality Risk

MONDAY, Nov. 12 (HealthDay News) -- Baseline body mass index affects the odds of dying from prostate cancer, according to the results of a study published online Nov. 12 in the journal Cancer.

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Cases of Alcohol Binge-Related Bladder Rupture Described

FRIDAY, Nov. 9 (HealthDay News) -- Clinicians should consider bladder rupture as a potential cause of abdominal pain in women who report binge drinking, according to an article published in the Nov. 10 issue of BMJ.

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FDA: Erythropoiesis-Stimulating Agent Labels Revised

FRIDAY, Nov. 9 (HealthDay News) -- Revised boxed warnings for erythropoiesis-stimulating agents (ESAs) such as Aranesp, Epogen and Procrit -- which are used to treat anemia -- were approved Nov. 8 by the U.S. Food and Drug Administration to address risks that such drugs represent to patients with conditions including cancer and chronic kidney failure.

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Study Examines Mortality Risk in Acute Urinary Retention

FRIDAY, Nov. 9 (HealthDay News) -- Mortality rates in men hospitalized for a first episode of acute urinary retention are high, with one in four men dying within a year when the cause of urinary retention is unrelated to prostatic enlargement, and one in seven dying when prostatic enlargement is the cause, according to a report published online Nov. 8 in BMJ Online First.

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Parent's Cancer Survival May Predict Child's Cancer Survival

MONDAY, Nov. 5 (HealthDay News) -- When a parent and a child both contract lung, colorectal, breast or prostate cancer, the post-diagnosis survival of the parent may predict the post-diagnosis survival of the child, researchers report in the November issue of The Lancet Oncology.

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Classification Rule Aids in Detection of Prostate Cancer

THURSDAY, Nov. 1 (HealthDay News) -- A statistically based classification rule that incorporates polyamine information with the choline plus citrate-creatine ratio aids radiologists in detecting prostate cancer with magnetic resonance (MR) spectroscopic imaging, according to a report published in the November issue of Radiology.

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