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Therapy Found Effective for Overactive Bladder Syndrome

Percutaneous tibial nerve stimulation markedly improves symptoms compared to sham therapy

MONDAY, April 5 (HealthDay News) -- In patients with overactive bladder syndrome, percutaneous tibial nerve stimulation therapy may be safe and effective, according to a study in the April issue of The Journal of Urology.

Kenneth M. Peters, M.D., of Beaumont Hospital in Royal Oak, Mich., and colleagues randomly assigned 220 adults with overactive bladder symptoms to receive either 12 weeks of treatment with weekly percutaneous tibial nerve stimulation or sham therapy.

The researchers found that a significantly higher proportion of the percutaneous tibial nerve stimulation group reported moderately or markedly improved responses than the sham therapy group (54.5 versus 20.9 percent). Compared to the sham group, the percutaneous tibial nerve stimulation group had statistically significant improvements in frequency, nighttime voids, voids with moderate to severe urgency and urinary urge incontinence episodes, and there were no reported serious device-related adverse events or malfunctions.

"The compelling efficacy of percutaneous tibial nerve stimulation demonstrated in this trial is consistent with other recently published reports and supports the use of peripheral neuromodulation therapy for overactive bladder," the authors conclude.

The study was supported by Uroplasty Inc.; several authors reported financial relationships with Uroplasty and other companies.

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